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Results for “Relapsed and Refractory Acute Leukemia”

1,775 trials

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Showing 20 of 1,775 results

Testing effectiveness (Phase 2)Study completedNCT00040846
What this trial is testing

Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+97 more
Fred Hutchinson Cancer Center 60
Early research (Phase 1)Looking for participantsNCT07586618
What this trial is testing

First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect.

Who this might be right for
Lymphoblastic LymphomaAcute Lymphoblastic Leukemia ALL
Allterum Therapeutics, Inc 24
Early research (Phase 1)Looking for participantsNCT07239323
What this trial is testing

In VIVO CAR-T Therapy for Relapsed/Refractory Hematological Malignancies

Who this might be right for
B-Acute Lymphoblastic LeukemiaB Cell Non-Hodgkin's LymphomaMultiple Myeloma
Chongqing Precision Biotech Co., Ltd 24
Testing effectiveness (Phase 2)Looking for participantsNCT04588922
What this trial is testing

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Who this might be right for
Hematologic Malignancies
Sellas Life Sciences Group 160
Testing effectiveness (Phase 2)Study completedNCT03097770
What this trial is testing

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20

Who this might be right for
Hematopoietic/Lymphoid CancerAdult Acute Lymphoblastic Leukemia in RemissionB-cell Adult Acute Lymphoblastic Leukemia+20 more
Chinese PLA General Hospital 100
Not applicableNo Longer AvailableNCT03746912
What this trial is testing

Expanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) to Receive Quizartinib

Who this might be right for
Acute Myeloid Leukemia With Gene Mutations
Daiichi Sankyo
Early research (Phase 1)Ended earlyNCT03922477
What this trial is testing

A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/or Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Hoffmann-La Roche 13
Early research (Phase 1)Study completedNCT00900809
What this trial is testing

QUILT-3.018: Neukoplast™ (NK-92) for the Treatment of Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
ImmunityBio, Inc. 7
Early research (Phase 1)Ended earlyNCT00928200
What this trial is testing

Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)

Who this might be right for
Relapsed Acute Lymphoblastic LeukemiaAllergy to PEG e.Coli AsparaginaseAllergy to Native e.Coli Asparaginase
Therapeutic Advances in Childhood Leukemia Consortium 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT03573700
What this trial is testing

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, Refractory
St. Jude Children's Research Hospital 24
Early research (Phase 1)UnknownNCT06367673
What this trial is testing

Natural Killer(NK) Cell Therapy Targeting CLL1 or CD33 in Acute Myeloid Leukemia

Who this might be right for
AML, Adult
Zhejiang University 24
Early research (Phase 1)Ended earlyNCT03135028
What this trial is testing

Entospletinib (ENTO) as Monotherapy and in Combination With Chemotherapy in Japanese Adults

Who this might be right for
Hematologic MalignancyAcute Myeloid Leukemia
Gilead Sciences 9
Early research (Phase 1)Study completedNCT03263637
What this trial is testing

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Who this might be right for
Relapsed or Refractory Haematological Malignancies IncludingAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+8 more
AstraZeneca 44
Not applicableEnded earlyNCT05247957
What this trial is testing

NKG2D CAR-NK Cell Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Safety and Efficacy
Hangzhou Cheetah Cell Therapeutics Co., Ltd 9
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)Active Not RecruitingNCT04521231
What this trial is testing

Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL

Who this might be right for
B Cell Precursor Acute Lymphoblastic Leukemia
Amgen 181
Testing effectiveness (Phase 2)Active Not RecruitingNCT02981628
What this trial is testing

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent B Lymphoblastic LymphomaRefractory B Acute Lymphoblastic Leukemia+1 more
Children's Oncology Group 80
Testing effectiveness (Phase 2)Looking for participantsNCT06585345
What this trial is testing

Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell in Patients With Relapsed/Refractory Acute Leukemia

Who this might be right for
Acute-Leukemia
The General Hospital of Western Theater Command 200
Not applicableStudy completedNCT02003612
What this trial is testing

Historical Data Analysis of Hematological Remission and Survival in Adults With R/R Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Amgen 2,373
Large-scale testing (Phase 3)Looking for participantsNCT07570173
What this trial is testing

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Merck Sharp & Dohme LLC 340
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