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Results for “Remyelination”

35 trials

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Showing 20 of 35 results

Post-approval studies (Phase 4)UnknownNCT05902429
What this trial is testing

Effects of Oral Cladribine on Remyelination and Inflammation in Multiple Sclerosis Patients

Who this might be right for
Multiple Sclerosis, Relapsing-Remitting
Pontificia Universidade Católica do Rio Grande do Sul 10
Testing effectiveness (Phase 2)Study completedNCT01772199
What this trial is testing

Study to Assess Whether GSK239512 Can Remyelinate Lesions in Subjects With Relapsing Remitting Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Relapsing-Remitting
GlaxoSmithKline 131
Not applicableUnknownNCT04042363
What this trial is testing

Effect of Transorbital Electrical STIMulation of Optic Nerve on Remyelination After an Acute Optic Neuritis

Who this might be right for
Multiple SclerosisOptic Neuritis
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT05893225
What this trial is testing

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple SclerosisSecondary-progressive Multiple Sclerosis
University Hospital, Antwerp 120
Testing effectiveness (Phase 2)Looking for participantsNCT04121468
What this trial is testing

A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS)
The Hospital for Sick Children 20
Testing effectiveness (Phase 2)Study completedNCT05131828
What this trial is testing

CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

Who this might be right for
Multiple Sclerosis
Cambridge University Hospitals NHS Foundation Trust 70
Not applicableLooking for participantsNCT05258396
What this trial is testing

Exploring Cortical Remyelination in Children With Multiple Sclerosis

Who this might be right for
Children With Multiple Sclerosis
Assistance Publique - Hôpitaux de Paris 40
Testing effectiveness (Phase 2)Ended earlyNCT03536559
What this trial is testing

Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis

Who this might be right for
Relapsing Remitting Multiple SclerosisOptic NeuropathyOptic; Neuritis, With Demyelination
Clene Nanomedicine 73
Early research (Phase 1)Study completedNCT02521545
What this trial is testing

Single-Dose Study of a New Formulation of BIIB061

Who this might be right for
Multiple Sclerosis
Biogen 8
Early research (Phase 1)Study completedNCT01244139
What this trial is testing

Safety Study of BIIB033 in Subjects With Multiple Sclerosis

Who this might be right for
Relapsing-Remitting Multiple SclerosisMultiple Sclerosis
Biogen 47
Early research (Phase 1)Ended earlyNCT06617546
What this trial is testing

SAD and MAD Study of FTX-101 in Healthy Male Subjects

Who this might be right for
Healthy Volunteers
Find Therapeutics 49
Not applicableStudy completedNCT00937677
What this trial is testing

Effect of Tysabri in Patients With Relapsing-Remitting Multiple Sclerosis: A Follow-up Magnetization Transfer Imaging (MTI) Study

Who this might be right for
Multiple Sclerosis
University at Buffalo 85
Large-scale testing (Phase 3)Looking for participantsNCT05338450
What this trial is testing

Clemastine Fumarate as Remyelinating Treatment in Internuclear Ophthalmoparesis and Multiple Sclerosis

Who this might be right for
Multiple SclerosisInternuclear Ophthalmoplegia
Amsterdam UMC, location VUmc 80
Testing effectiveness (Phase 2)Study completedNCT02493049
What this trial is testing

Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis (RRMS)

Who this might be right for
Multiple Sclerosis, Relapsing-Remitting
University of Calgary 17
Testing effectiveness (Phase 2)Looking for participantsNCT07304024
What this trial is testing

A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound

Who this might be right for
Central Auditory Processing DisorderHearing Impaired (Partially)Hearing+23 more
University of Colorado, Denver 344
Testing effectiveness (Phase 2)Ended earlyNCT03222973
What this trial is testing

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)

Who this might be right for
Multiple Sclerosis
Biogen 263
Early research (Phase 1)Study completedNCT06683612
What this trial is testing

PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF

Who this might be right for
Idiopathic Pulmonary Fibrosis (IPF)Idiopathic Pulmonary FibrosisMultiple Sclerosis+6 more
Contineum Therapeutics 16
Not applicableUnknownNCT01918501
What this trial is testing

Testing Mitochondria Activity and Blood Lipid Content of Multiple Sclerosis Patients

Who this might be right for
Multiple Sclerosis
Ziv Hospital 120
Not applicableUnknownNCT05147532
What this trial is testing

Remyelination in Multiple Sclerosis: a PET-MR Longitudinal Study Investigating Individual Profiles of Myelin Repair and the Contribution of Neuroinflammation

Who this might be right for
Multiple SclerosisInflammatory Disease
Assistance Publique - Hôpitaux de Paris 80
Not applicableStudy completedNCT05783934
What this trial is testing

Demyelination and Remyelination in Multiple Sclerosis (MS) Detected by Brain Amyloid PET-CT

Who this might be right for
Multiple Sclerosis
Istituti Clinici Scientifici Maugeri SpA 6
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