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Results for “Resistance to Immunotherapy”

72 trials

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Showing 20 of 72 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07022301
What this trial is testing

Sintilimab Plus Anlotinib as Second or Further-line Therapy for ES-SCLC Who Have Progressed After Anti-PD-1/L1 Therapy

Who this might be right for
Small Cell Lung Cancer Extensive StageResistance to Immunotherapy
First Affiliated Hospital of Wannan Medical College 25
Testing effectiveness (Phase 2)Study completedNCT02105675
What this trial is testing

Phase II Study of DCVAC/PCa Added to Standard Chemotherapy for Men With Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Prostate CancerProstate Cancer Metastatic
SOTIO a.s. 60
Early research (Phase 1)Looking for participantsNCT06439836
What this trial is testing

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Who this might be right for
Metastatic Urothelial CarcinomaUnresectable Urothelial Carcinoma
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Ended earlyNCT02554812
What this trial is testing

Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

Who this might be right for
Advanced Cancer
Pfizer 409
Testing effectiveness (Phase 2)Study completedNCT03262779
What this trial is testing

Ipilimumab and Nivolumab in Patients With Anti-PD-1-axis Therapy-resistant Advanced Non-small Cell Lung Cancer.

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Yale University 20
Testing effectiveness (Phase 2)Looking for participantsNCT07071103
What this trial is testing

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Malignant Solid Tumors

Who this might be right for
RadiotherapyMetastatic Solid CancersImmune Checkpoint Blockade+3 more
Chuangzhen Chen 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT05664243
What this trial is testing

A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma
In8bio Inc. 4
Testing effectiveness (Phase 2)Looking for participantsNCT05690048
What this trial is testing

Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA)

Who this might be right for
ImmunotherapyHCC - Hepatocellular Carcinoma
Michael Dill 48
Very early researchNot Yet RecruitingNCT06364800
What this trial is testing

Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody

Who this might be right for
Hepatocellular Carcinoma
Beijing 302 Hospital 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07288034
What this trial is testing

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

Who this might be right for
Lung Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8Stage IV Lung Cancer AJCC v8
City of Hope Medical Center 535
Testing effectiveness (Phase 2)Study completedNCT04225390
What this trial is testing

Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy

Who this might be right for
Immunotherapy
University of Erlangen-Nürnberg Medical School 38
Early research (Phase 1)Not Yet RecruitingNCT06622174
What this trial is testing

Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

Who this might be right for
Non Small Cell Lung CancerMetastatic Lung Cancer
Houda Bahig 32
Testing effectiveness (Phase 2)Looking for participantsNCT04071236
What this trial is testing

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

Who this might be right for
Metastatic Castration-Resistant Prostate CarcinomaMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the Lymph Nodes+1 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)WithdrawnNCT05022394
What this trial is testing

Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study

Who this might be right for
Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage I Lung Cancer AJCC v8+10 more
M.D. Anderson Cancer Center
Early research (Phase 1)Ended earlyNCT04615845
What this trial is testing

Safety Evaluation of Autologous Dendritic Cell Anticancer Immune Cell Therapy (Cellgram-DC-PC)

Who this might be right for
Castration Resistant Prostate Cancer, CRPC
Pharmicell Co., Ltd. 3
Testing effectiveness (Phase 2)WithdrawnNCT00348842
What this trial is testing

Newcastle Disease Virus (NDV) for Cancer Patients Resistant to Conventional Anti-cancer Modalities

Who this might be right for
Metastatic CancerNewcastle Disease Virus (NDV)
Hadassah Medical Organization
Testing effectiveness (Phase 2)Study completedNCT05304546
What this trial is testing

Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma

Who this might be right for
Malignant MelanomaMetastatic MelanomaImmunotherapy+2 more
Dr. Ronnie Shapira 1
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07014215
What this trial is testing

PD-1 Combined With Bevacizumab and PCSK-9 Inhibitor in Patients With Advanced NSCLC Who Have Progressed After Anti- PD- 1/L1 Therapy

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)Resistance to Immunotherapy
Anhui Provincial Cancer Hospital 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07158489
What this trial is testing

Overcoming Resistance to Immunotherapy Combining Gemcitabine With Ivonescimab in Advanced NSCLC

Who this might be right for
NSCLCNSCLC (Advanced Non-small Cell Lung Cancer)
Swiss Cancer Institute 47
Testing effectiveness (Phase 2)Looking for participantsNCT06490068
What this trial is testing

Study of LTC004 Combine With Toripalimab in Patient With Solid Tumors Resistant to Immunotherapy

Who this might be right for
Advanced Solid Tumor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 10
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