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Results for “Reversal of Coagulopathy”

14 trials

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Showing 14 of 14 results

Large-scale testing (Phase 3)Study completedNCT00168077
What this trial is testing

Prothrombin Complex Concentrate for Anticoagulant Reversal

Who this might be right for
Acquired Coagulation Factor Deficiency
CSL Behring 40
Large-scale testing (Phase 3)Study completedNCT02281201
What this trial is testing

Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects

Who this might be right for
Acute Major BleedingReversal of Coagulopathy
CSL Behring 11
Testing effectiveness (Phase 2)UnknownNCT02463591
What this trial is testing

Reversal of Dabigatran With Prothrombin Complex Concentrate

Who this might be right for
Drug Action Reversal
University Medical Center Groningen 12
Large-scale testing (Phase 3)Study completedNCT02740335
What this trial is testing

Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.

Who this might be right for
Significant Bleeding Risk
Octapharma 208
Post-approval studies (Phase 4)Study completedNCT03064035
What this trial is testing

Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal

Who this might be right for
Acute Bleeding on Long-Term Anticoagulation TherapyHemorrhageSignificant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time)+1 more
HealthPartners Institute 79
Not applicableStudy completedNCT03267823
What this trial is testing

INR Comparison Testing in Cardiac Surgery

Who this might be right for
Coagulation Disorder
University of Miami 50
Large-scale testing (Phase 3)Study completedNCT00708435
What this trial is testing

Efficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant Therapy

Who this might be right for
Blood Coagulation DisordersAcute Major Bleeding
CSL Behring 216
Large-scale testing (Phase 3)Study completedNCT00618098
What this trial is testing

Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures

Who this might be right for
Reversal of Anticoagulant Treatment
Octapharma 200
Not applicableWithdrawnNCT02429453
What this trial is testing

FFP Versus PCC in Intracranial Hemorrhage

Who this might be right for
Intracranial Hemorrhage, TraumaticIntracranial Hemorrhage, Spontaneous
University of Utah
Not applicableStudy completedNCT01727830
What this trial is testing

Hemodilution and Coagulopathy With 3 Colloids

Who this might be right for
Dilutional Coagulopathy
University of Zurich 12
Large-scale testing (Phase 3)Ended earlyNCT01545635
What this trial is testing

RETIC Trial: Reversal of Trauma Induced Coagulopathy Using Coagulation Factor Concentrates or Fresh Frozen Plasma

Who this might be right for
Major Trauma
Medical University Innsbruck 100
Large-scale testing (Phase 3)Study completedNCT00803101
What this trial is testing

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Procedure

Who this might be right for
Reversal of Coagulopathy
CSL Behring 176
Large-scale testing (Phase 3)Looking for participantsNCT05156983
What this trial is testing

TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery

Who this might be right for
Coagulation Disorder
Takeda 328
Not applicableLooking for participantsNCT06429787
What this trial is testing

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Who this might be right for
Vitamin K-Dependent Coagulation DefectSignificant Bleeding Risk
Octapharma 3,574