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Results for “Richter's Syndrome”

82 trials

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Showing 20 of 82 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04082897
What this trial is testing

ObinutuzuMab AtezOlizumab and VenetocLax in RichTer transfOrmation

Who this might be right for
CLL Transformation
Niguarda Hospital 28
Testing effectiveness (Phase 2)Ended earlyNCT02378038
What this trial is testing

PNT2258 for Treatment of Patients With Richter's Transformation (Brighton)

Who this might be right for
Richter's Transformation
Sierra Oncology LLC - a GSK company 5
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
Early research (Phase 1)WithdrawnNCT04781855
What this trial is testing

Ipilimumab, Ibrutinib, and Nivolumab for the Treatment of Chronic Lymphocytic Leukemia and Richter Transformation

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmRecurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic Lymphoma+3 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT04660045
What this trial is testing

Early Intervention With Acalabrutinib in Patients With High Risk CLL

Who this might be right for
Chronic Lymphocytic LeukemiaCLL/SLL
Weill Medical College of Cornell University
Early research (Phase 1)Enrolling By InvitationNCT07168486
What this trial is testing

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

Who this might be right for
B-Cell LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
University of Maryland, Baltimore 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT03534323
What this trial is testing

Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS

Who this might be right for
Chronic Lymphocytic LeukemiaRichter Syndrome
Dana-Farber Cancer Institute 67
Early research (Phase 1)Study completedNCT03263637
What this trial is testing

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Who this might be right for
Relapsed or Refractory Haematological Malignancies IncludingAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+8 more
AstraZeneca 44
Testing effectiveness (Phase 2)Looking for participantsNCT06926205
What this trial is testing

CHOP Plus Mosunetuzumab as First Line in Patients With Richter´s Syndrome: a Phase II Study of the Spanish Group of CLL

Who this might be right for
Richter Syndrome
GELLC (Grupo Español de Leucemia Linfocítica Crónica) 34
Testing effectiveness (Phase 2)Looking for participantsNCT04679012
What this trial is testing

Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation

Who this might be right for
Richter SyndromeChronic Lymphocytic Leukemia
Weill Medical College of Cornell University 20
Testing effectiveness (Phase 2)Looking for participantsNCT06936943
What this trial is testing

ONO-4538 Study in Patients With Richter's Transformation

Who this might be right for
Richter's Transformation
Ono Pharmaceutical Co. Ltd 14
Testing effectiveness (Phase 2)Looking for participantsNCT05458297
What this trial is testing

Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

Who this might be right for
Chronic Lymphocytic LeukemiaMantle Cell LymphomaFollicular Lymphoma+1 more
Merck Sharp & Dohme LLC 223
Early research (Phase 1)Looking for participantsNCT05107674
What this trial is testing

NX-1607 in Adults With Advanced Malignancies

Who this might be right for
Ovarian Cancer, EpithelialGastric CancerGastroEsophageal Junction (GEJ) Cancer+11 more
Nurix Therapeutics, Inc. 345
Testing effectiveness (Phase 2)Study completedNCT00304005
What this trial is testing

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Who this might be right for
LeukemiaLymphoma
Vion Pharmaceuticals 35
Early research (Phase 1)Study completedNCT03833180
What this trial is testing

Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)

Who this might be right for
Chronic Lymphocytic LeukemiaMantle Cell LymphomaFollicular Lymphoma+9 more
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 91
Early research (Phase 1)Looking for participantsNCT04771572
What this trial is testing

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Who this might be right for
Non Hodgkin LymphomaRichter TransformationMultiple Myeloma+10 more
Newave Pharmaceutical Inc 100
Early research (Phase 1)Study completedNCT01254578
What this trial is testing

Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers

Who this might be right for
Adult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11+39 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Study completedNCT00472849
What this trial is testing

Oxaliplatin, Fludarabine, Cytarabine, and Rituximab in Patients With Richter's Transformation and Leukemias

Who this might be right for
Richter's TransformationLeukemia
M.D. Anderson Cancer Center 92
Large-scale testing (Phase 3)Not Yet RecruitingNCT07220187
What this trial is testing

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

Who this might be right for
Richter SyndromeTransformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell LymphomaTransformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma
SWOG Cancer Research Network 102
Testing effectiveness (Phase 2)Study completedNCT01171378
What this trial is testing

Study of Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone (CHOP) With Ofatumumab in Patients With Richter's Syndrome

Who this might be right for
Richter's Syndrome
University of Oxford 43
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