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Results for “Richter Syndrome”

84 trials

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Showing 20 of 84 results

Early research (Phase 1)Study completedNCT03833180
What this trial is testing

Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)

Who this might be right for
Chronic Lymphocytic LeukemiaMantle Cell LymphomaFollicular Lymphoma+9 more
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 91
Not applicableNot Yet RecruitingNCT05923502
What this trial is testing

(CHANT)Real World Study of Duvelisib in the Treatment of Non-Hodgkin's Lymphoma (NHL)

Who this might be right for
Follicular LymphomaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRichter Syndrome+3 more
Ruijin Hospital 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT03162536
What this trial is testing

Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

Who this might be right for
Lymphoma, B-CellSmall Lymphocytic LymphomaChronic Lymphocytic Leukemia+6 more
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 190
Testing effectiveness (Phase 2)Active Not RecruitingNCT04623541
What this trial is testing

Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome

Who this might be right for
Relapsed/Refractory Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaRichter's Syndrome+1 more
Genmab 195
Early research (Phase 1)Not Yet RecruitingNCT07451054
What this trial is testing

CD45BE-HSPC + CART-45 Cells

Who this might be right for
B-Cell Non-Hodgkin Lymphoma (NHL)Richter's TransformationT-Cell Non-Hodgkin Lymphoma+1 more
University of Pennsylvania 42
Testing effectiveness (Phase 2)Ended earlyNCT02378038
What this trial is testing

PNT2258 for Treatment of Patients With Richter's Transformation (Brighton)

Who this might be right for
Richter's Transformation
Sierra Oncology LLC - a GSK company 5
Early research (Phase 1)Looking for participantsNCT06735664
What this trial is testing

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

Who this might be right for
Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaRichter Syndrome+1 more
City of Hope Medical Center 23
Testing effectiveness (Phase 2)Study completedNCT02362035
What this trial is testing

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

Who this might be right for
Follicular Lymphoma (FL)CLLSmall Lymphocytic Lymphoma (SLL)+10 more
Acerta Pharma BV 161
Testing effectiveness (Phase 2)Looking for participantsNCT05294731
What this trial is testing

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

Who this might be right for
B-cell MalignancyNon-Hodgkin LymphomaMantle Cell Lymphoma+6 more
BeiGene 146
Testing effectiveness (Phase 2)Ended earlyNCT05537766
What this trial is testing

Study of Brexucabtagene Autoleucel in Adults With Rare B-cell Malignancies

Who this might be right for
Relapsed/Refractory Waldenstrom MacroglobulinemiaRelapsed/Refractory Richter TransformationRelapsed/Refractory Burkitt Lymphoma+1 more
Kite, A Gilead Company 19
Early research (Phase 1)Looking for participantsNCT04771572
What this trial is testing

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Who this might be right for
Non Hodgkin LymphomaRichter TransformationMultiple Myeloma+10 more
Newave Pharmaceutical Inc 100
Early research (Phase 1)Ended earlyNCT03778073
What this trial is testing

Study of Cosibelimab in Subjects With Relapsed or Refractory Lymphoma

Who this might be right for
B-cell Non Hodgkin LymphomaRichter's Transformation
TG Therapeutics, Inc. 18
Early research (Phase 1)Active Not RecruitingNCT05828589
What this trial is testing

BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

Who this might be right for
Relapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin LymphomaRelapsed Chronic Lymphocytic Leukemia+11 more
BeOne Medicines 112
Testing effectiveness (Phase 2)Looking for participantsNCT04271956
What this trial is testing

Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation

Who this might be right for
Richter Transformation
German CLL Study Group 83
Early research (Phase 1)Study completedNCT02535286
What this trial is testing

Study of Immunotherapy in Combination With Ublituximab and Umbralisib in Patients With Relapsed-refractory CLL or Richter's Transformation

Who this might be right for
Chronic Lymphocytic LeukemiaRichter Syndrome
TG Therapeutics, Inc. 27
Testing effectiveness (Phase 2)Study completedNCT04939363
What this trial is testing

Evaluate Efficacy & Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Richter's Syndrome;

Who this might be right for
Richter's Syndrome
Bnai Zion Medical Center 12
Testing effectiveness (Phase 2)Study completedNCT02332980
What this trial is testing

Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas

Who this might be right for
Recurrent B-Cell Non-Hodgkin LymphomaRecurrent Chronic Lymphocytic LeukemiaRecurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue+20 more
Mayo Clinic 65
Testing effectiveness (Phase 2)Looking for participantsNCT06926205
What this trial is testing

CHOP Plus Mosunetuzumab as First Line in Patients With Richter´s Syndrome: a Phase II Study of the Spanish Group of CLL

Who this might be right for
Richter Syndrome
GELLC (Grupo Español de Leucemia Linfocítica Crónica) 34
Testing effectiveness (Phase 2)Study completedNCT01217749
What this trial is testing

Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLL

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaProlymphocyctic Leukemia+1 more
Pharmacyclics LLC. 71
Not applicableUnknownNCT03619512
What this trial is testing

Genomic and Proteomic Study of Richter Syndrome (CGPSR)

Who this might be right for
Richter Syndrome
Central Hospital, Nancy, France 170
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