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Results for “Richter Transformation”

88 trials

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Showing 20 of 88 results

Testing effectiveness (Phase 2)Study completedNCT00304005
What this trial is testing

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Who this might be right for
LeukemiaLymphoma
Vion Pharmaceuticals 35
Testing effectiveness (Phase 2)WithdrawnNCT02285244
What this trial is testing

Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, Prolymphocytic Leukemia, or Richter's Transformation

Who this might be right for
Prolymphocytic LeukemiaRecurrent Mantle Cell LymphomaRecurrent Small Lymphocytic Lymphoma+2 more
James Blachly
Early research (Phase 1)Active Not RecruitingNCT03884998
What this trial is testing

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaDiffuse Large B-Cell LymphomaFollicular Lymphoma+4 more
City of Hope Medical Center 27
Testing effectiveness (Phase 2)UnknownNCT04992377
What this trial is testing

R-EPOCH in Combination With Ibrutinib for Patients With Classical RT of CLL

Who this might be right for
Richter Transformation
Institute of Hematology & Blood Diseases Hospital, China 30
Testing effectiveness (Phase 2)Ended earlyNCT06561425
What this trial is testing

A Study Evaluating the Safety and Efficacy of GLPG5101 (19CP02) in Participants With Non-Hodgkin Lymphoma

Who this might be right for
Relapsed/Refractory B-cell Non-Hodgkin LymphomaLymphomas Non-Hodgkin&Amp;Amp;#39;s B-Cell
Lakefront Biotherapeutics NV 130
Early research (Phase 1)Study completedNCT02535286
What this trial is testing

Study of Immunotherapy in Combination With Ublituximab and Umbralisib in Patients With Relapsed-refractory CLL or Richter's Transformation

Who this might be right for
Chronic Lymphocytic LeukemiaRichter Syndrome
TG Therapeutics, Inc. 27
Early research (Phase 1)Ended earlyNCT03778073
What this trial is testing

Study of Cosibelimab in Subjects With Relapsed or Refractory Lymphoma

Who this might be right for
B-cell Non Hodgkin LymphomaRichter's Transformation
TG Therapeutics, Inc. 18
Testing effectiveness (Phase 2)WithdrawnNCT06247540
What this trial is testing

Venetoclax, Rituximab and Nivolumab in Combination for the Treatment of Richter's Transformation Arising From Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaRichter Syndrome+2 more
Northwestern University
Testing effectiveness (Phase 2)Study completedNCT02420912
What this trial is testing

Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation

Who this might be right for
Loss of Chromosome 17pRecurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic Lymphoma+3 more
M.D. Anderson Cancer Center 37
Testing effectiveness (Phase 2)Study completedNCT03010358
What this trial is testing

Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma

Who this might be right for
AnemiaB-Cell Prolymphocytic LeukemiaGrade 1 Follicular Lymphoma+11 more
Alexey Danilov, MD 24
Early research (Phase 1)Ended earlyNCT04978779
What this trial is testing

Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

Who this might be right for
Relapsed Non Hodgkin LymphomaChronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic Leukemia+4 more
Vincerx Pharma, Inc. 6
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics Incorporated 86
Testing effectiveness (Phase 2)Active Not RecruitingNCT03054896
What this trial is testing

A Phase II Study of Venetoclax in Combination With Dose-adjusted EPOCH-R or R-CHOP for Patients With Richter's Syndrome

Who this might be right for
Richter Syndrome
Dana-Farber Cancer Institute 69
Testing effectiveness (Phase 2)Looking for participantsNCT04271956
What this trial is testing

Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment With or Without Sonrotoclax for Patients With Richter Transformation

Who this might be right for
Richter Transformation
German CLL Study Group 83
Testing effectiveness (Phase 2)Looking for participantsNCT06936943
What this trial is testing

ONO-4538 Study in Patients With Richter's Transformation

Who this might be right for
Richter's Transformation
Ono Pharmaceutical Co., Ltd. 14
Early research (Phase 1)Looking for participantsNCT07451054
What this trial is testing

CD45BE-HSPC + CART-45 Cells

Who this might be right for
B-Cell Non-Hodgkin Lymphoma (NHL)Richter's TransformationT-Cell Non-Hodgkin Lymphoma+1 more
University of Pennsylvania 42
Testing effectiveness (Phase 2)Looking for participantsNCT06043674
What this trial is testing

Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

Who this might be right for
Chronic Lymphocytic LeukemiaRichter's Transformation
Christine Ryan 70
Testing effectiveness (Phase 2)Looking for participantsNCT04679012
What this trial is testing

Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation

Who this might be right for
Richter SyndromeChronic Lymphocytic Leukemia
Weill Medical College of Cornell University 20
Not applicableLooking for participantsNCT02863692
What this trial is testing

Registry of the German CLL Study Group

Who this might be right for
CLLSLLHCL+5 more
German CLL Study Group 8,000
Early research (Phase 1)Looking for participantsNCT06735664
What this trial is testing

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

Who this might be right for
Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaRichter Syndrome+1 more
City of Hope Medical Center 23
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