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Results for “SGLT2-Inhibitors”

381 trials

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Showing 20 of 381 results

Post-approval studies (Phase 4)Looking for participantsNCT06291155
What this trial is testing

Mechanism of SGLT2 Inhibition in the Kidney

Who this might be right for
Type 2 DiabetesDiabetic Kidney Disease
University of Michigan 20
Not applicableStudy completedNCT07269197
What this trial is testing

Association of SGLT2 Inhibitors Therapy With Elastographic and Molecular Markers of Liver Injury in Type 2 Diabetes

Who this might be right for
Non-Alcoholic Fatty Liver DiseaseDiabetes Mellitus, Type 2
Josip Juraj Strossmayer University of Osijek 67
Not applicableLooking for participantsNCT07491042
What this trial is testing

Impact of SGLT2 Inhibitors on Chronic Peritoneal Dialysis Patients.

Who this might be right for
End Stage Chronic Renal Failure
Oman Ministry of Health 38
Large-scale testing (Phase 3)Not Yet RecruitingNCT07488689
What this trial is testing

Assessing the Efficacy of Dapagliflozin as a Vasculoprotective Treatment in Septic Shock Patients With Microcirculatory Dysfunction

Who this might be right for
Septic Shock
University Hospital, Strasbourg, France 568
Post-approval studies (Phase 4)Not Yet RecruitingNCT07527390
What this trial is testing

CANagliflozin In DIALysis Patients

Who this might be right for
DialysisChronic Kidney Disease (Stages 4 and 5)
University Medical Center Groningen 10
Testing effectiveness (Phase 2)Looking for participantsNCT07245069
What this trial is testing

Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients

Who this might be right for
Heart FailureAnthracycline-induced Cardiac ToxicityEndothelial Function (FMD)+2 more
University Medical Centre Ljubljana 100
Not applicableEnded earlyNCT06094231
What this trial is testing

Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study

Who this might be right for
Chronic Kidney DiseasesDiabetes MellitusPreDiabetes+1 more
Department of Nephrology Clinic Ottakring Vienna 4
Not applicableActive Not RecruitingNCT06491953
What this trial is testing

SGLT2-inhibitors on PC-AKI

Who this might be right for
Impact of SGLT2-inhibitors on PC-AKI in ACS Patients Receiving Invasive Strategy
Shenyang Northern Hospital 3,600
Large-scale testing (Phase 3)Active Not RecruitingNCT06260722
What this trial is testing

Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

Who this might be right for
Diabetes Mellitus, Type 2
Eli Lilly and Company 1,250
Not applicableStudy completedNCT03918148
What this trial is testing

Gliflozins and Cardiovascular Risk Factors in Type 2 Diabetes (GIOIA)

Who this might be right for
Type 2 Diabetes Mellitus
University of Campania Luigi Vanvitelli 1,150
Large-scale testing (Phase 3)Looking for participantsNCT06142474
What this trial is testing

SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning

Who this might be right for
Heart Failure AcuteVentilator Lung
National Taiwan University Hospital 450
Testing effectiveness (Phase 2)Study completedNCT03922750
What this trial is testing

A Research Study in People With Type 2 Diabetes to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine

Who this might be right for
Diabetes Mellitus, Type 2
Novo Nordisk A/S 154
Large-scale testing (Phase 3)UnknownNCT05776043
What this trial is testing

Empagliflozin and Dapagliflozin in Patients Hospitalized for Acute Decompensated Heart Failure

Who this might be right for
Acute Decompensated Heart Failure
Medical University of Warsaw 1,364
Testing effectiveness (Phase 2)Looking for participantsNCT05884866
What this trial is testing

Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease.

Who this might be right for
Chronic Renal FailureMechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte HomeostatisChronic Kidney Disease Stage 3+1 more
Klinikum Nürnberg
Testing effectiveness (Phase 2)Study completedNCT06888505
What this trial is testing

Dapagliflozin to Prevent Anthracycline-Induced Cardiotoxicity

Who this might be right for
Anthracyclines-Induced CardiotoxicityCardiotoxicity
Hawler Medical University 90
Early research (Phase 1)Looking for participantsNCT06600178
What this trial is testing

Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)

Who this might be right for
Angina Patients With Non-obstructive Coronary Artery DiseaseCoronary Microvascular DiseaseCoronary Microvascular Dysfunction (CMD)
University of Virginia 150
Post-approval studies (Phase 4)Study completedNCT06026787
What this trial is testing

Clinical Value of Adding Dapagliflozin in Patients With Nephrotic Syndrome

Who this might be right for
Nephrotic SyndromeSodium-Glucose Transporter 2 Inhibitors
Ain Shams University 60
Post-approval studies (Phase 4)Study completedNCT06383832
What this trial is testing

Effect of Dapagliflozin on Body Weight in Overweight Women Consuming Different Proportions of Carbohydrate Diet.

Who this might be right for
OverweightCarbohydrateSodium-glucose Transporter 2 Inhibitors
Sun Jia 36
Not applicableUnknownNCT06326528
What this trial is testing

SGLT2 Inhibitors and Perioperative Period

Who this might be right for
Perioperative Complication
Assiut University 100
Early research (Phase 1)Study completedNCT00836225
What this trial is testing

Safety, Tolerability and Activity Study of Multiple Doses of ISIS-SGLT2Rx in Healthy Volunteers

Who this might be right for
Type 2 Diabetes Mellitus
Ionis Pharmaceuticals, Inc. 103
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