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Results for “SMARCA4-Deficient Tumor”

7 trials

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Showing 7 of 7 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05286801
What this trial is testing

Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

Who this might be right for
Atypical Teratoid/Rhabdoid TumorEpithelioid SarcomaKidney Medullary Carcinoma+15 more
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07200947
What this trial is testing

A Phase II Study of QL1706 and Platinum-Based Chemotherapy in Patients With SMARCA4-Deficient, Locally Advanced or Metastatic Non-Small Cell Lung Cancer.

Who this might be right for
SMARCA4-Deficient TumorLocally Advanced or Metastatic Non-Small Cell Lung Cancer
Zhijie Wang 28
Not applicableStudy completedNCT07121387
What this trial is testing

A Retrospective Cohort Analysis of SMARCA4-Deficient Lung Cancer

Who this might be right for
SMARCA4-Deficient TumorNSCLC (Advanced Non-small Cell Lung Cancer)
Shanghai Pulmonary Hospital, Shanghai, China 221
Testing effectiveness (Phase 2)Active Not RecruitingNCT04416568
What this trial is testing

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

Who this might be right for
Malignant Rhabdoid TumorRhabdoid Tumor of the KidneyEpithelioid Sarcoma+4 more
Dana-Farber Cancer Institute 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07307443
What this trial is testing

A Phase II Study of Anlotinib and Platinum-Based Chemotherapy in Patients With SMARCA4-Deficient, Locally Advanced or Metastatic Lung Cancer.

Who this might be right for
SMARCA4-Deficient TumorLocally Advanced or Metastatic Lung Cancer
Zhijie Wang 28
Early research (Phase 1)Looking for participantsNCT06561685
What this trial is testing

LY4050784 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Solid TumorAdvanced Solid TumorNon-small Cell Lung Cancer+1 more
Eli Lilly and Company 340
Testing effectiveness (Phase 2)Active Not RecruitingNCT05407441
What this trial is testing

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

Who this might be right for
Atypical Teratoid Rhabdoid TumorINI1 (SMARCB1)-Deficient Primary CNS Malignant TumorsSMARCA4-deficient Primary CNS Malignant Tumors+4 more
Susan Chi, MD 49