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Results for “Sacituzumab”

169 trials

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Showing 20 of 169 results

Early research (Phase 1)Active Not RecruitingNCT04794699
What this trial is testing

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Who this might be right for
Solid Tumor
IDEAYA Biosciences 169
Testing effectiveness (Phase 2)Looking for participantsNCT06616987
What this trial is testing

Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer

Who this might be right for
Breast Cancer Metastatic
Yeon Hee Park 40
Large-scale testing (Phase 3)Active Not RecruitingNCT05840211
What this trial is testing

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy

Who this might be right for
Locally Advanced or Unresectable Metastatic Breast CancerStage IV Breast Cancer
Gilead Sciences 654
Large-scale testing (Phase 3)Looking for participantsNCT06312137
What this trial is testing

Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Who this might be right for
Non Small Cell Lung Cancer
Merck Sharp & Dohme LLC 780
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07359404
What this trial is testing

Sacituzumab Govitecan Plus Bevacizumab in Metastatic TNBC

Who this might be right for
Advanced Breast Cancer
YING FAN 60
Testing effectiveness (Phase 2)Study completedNCT04143711
What this trial is testing

Study of DF1001 in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor, Adult
Dragonfly Therapeutics 270
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07134556
What this trial is testing

Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC

Who this might be right for
Triple Negative Breast CancerPDL-1 Positive
MedSIR 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06462079
What this trial is testing

Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases

Who this might be right for
Brain Metastasis
Guangzhou Medical University 43
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07511023
What this trial is testing

Phase 2 Trial Of Sacituzumab Tirumotecan For Treatment Of Refractory Metastatic Or Unresectable Squamous Cell Carcinoma Of The Anus/Rectum

Who this might be right for
Phase 2Sacituzumab TirumotecanRefractory Metastatic+2 more
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT04039230
What this trial is testing

Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.

Who this might be right for
Breast Cancer
Massachusetts General Hospital 75
Large-scale testing (Phase 3)Looking for participantsNCT06824467
What this trial is testing

Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Who this might be right for
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
Merck Sharp & Dohme LLC 770
Testing effectiveness (Phase 2)Looking for participantsNCT04724018
What this trial is testing

Sacituzumab Govitecan Plus EV in Metastatic UC

Who this might be right for
Urothelial CancerMetastatic Urothelial CarcinomaMetastatic Urothelial Carcinoma of the Renal Pelvis and Ureter+1 more
Dana-Farber Cancer Institute 106
Large-scale testing (Phase 3)Looking for participantsNCT06393374
What this trial is testing

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Who this might be right for
Triple-Negative Breast Cancer
Merck Sharp & Dohme LLC 1,530
Testing effectiveness (Phase 2)Looking for participantsNCT04559230
What this trial is testing

Sacituzumab Govitecan in Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma
The University of Texas Health Science Center at San Antonio 32
Large-scale testing (Phase 3)Study completedNCT03901339
What this trial is testing

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Participants With HR+/HER2- Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Gilead Sciences 543
Testing effectiveness (Phase 2)Looking for participantsNCT07339059
What this trial is testing

Phase II Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Cancer ( SCLC )Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Bindu R Potugari 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT05101096
What this trial is testing

Study of Sacituzumab Govitecan (SG) in Japanese Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Triple-Negative Breast CancerHR+/HER2- Metastatic Breast Cancer+1 more
Gilead Sciences 135
Testing effectiveness (Phase 2)Study completedNCT05520723
What this trial is testing

Preventive stRategy for IMMU132-relatED AEs in TNBC or Luminal Breast Cancer- PRIMED

Who this might be right for
Triple Negative Breast CancerBreast CancerAdvanced HR+/HER2- Breast Cancer
MedSIR 50
Not applicableNot Yet RecruitingNCT07168083
What this trial is testing

Efficacy and Safety of Sacituzumab in Patients With OCCC After Immunotherapy Progression

Who this might be right for
Ovarian CancerAntibody-drug ConjugatesClear Cell Adenocarcinoma of Ovary
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT05675579
What this trial is testing

A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)

Who this might be right for
Breast Cancer
M.D. Anderson Cancer Center 27
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