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Results for “Second-line Therapy”

1,248 trials

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Showing 20 of 1,248 results

Large-scale testing (Phase 3)Active Not RecruitingNCT02785952
What this trial is testing

Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers

Who this might be right for
Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network 275
Early research (Phase 1)Ended earlyNCT01534949
What this trial is testing

Provide Initial Evidence of Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy to Support the Pivotal CT-P10 Therapeutic Equivalence Trial

Who this might be right for
Diffuse Large B-Cell Lymphoma
Celltrion 1
Testing effectiveness (Phase 2)UnknownNCT02006043
What this trial is testing

Evaluate Erlotinib Efficacy and Safety as the 2nd/3rd Treatment in NSCLC With EGFR M(-) and C-met(-)

Who this might be right for
Non-small Cell Lung Cancer
Li Zhang 54
Testing effectiveness (Phase 2)Study completedNCT02113800
What this trial is testing

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study

Who this might be right for
Poorly Differentiated Malignant Neuroendocrine CarcinomaNeuroendocrine Carcinoma, Grade 3Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3+2 more
AIO-Studien-gGmbH
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07157306
What this trial is testing

Gecacitinib Combined With Donafenib and PD-1 Inhibitor as Immune Rechallenge Therapy for Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital 35
Not applicableStudy completedNCT06558084
What this trial is testing

Real-World Clinical Outcomes and Toxicity in Metastatic Breast Cancer Patients Treated With First or Second Line CDK 4/6 Inhibitors and Endocrine Therapy

Who this might be right for
Toxicity, DrugProgression, Disease
Ain Shams University 64
Not applicableStudy completedNCT02392455
What this trial is testing

VARGADO - Vargatef in 2nd-line Therapy of Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 817
Testing effectiveness (Phase 2)Active Not RecruitingNCT05012371
What this trial is testing

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

Who this might be right for
Advanced Clear Cell Renal Cell CarcinomaMetastatic Clear Cell Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8+1 more
M.D. Anderson Cancer Center 90
Testing effectiveness (Phase 2)Study completedNCT01082809
What this trial is testing

Sunitinib as Second-line Treatment in Advanced Biliary Tract Carcinoma

Who this might be right for
Advanced Biliary Tract Adenocarcinoma
Samsung Medical Center 59
Testing effectiveness (Phase 2)Ended earlyNCT01806649
What this trial is testing

BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line Chemotherapy

Who this might be right for
Esophageal Cancer
Prince of Songkla University 5
Large-scale testing (Phase 3)Study completedNCT03468335
What this trial is testing

2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy

Who this might be right for
Locally Advanced Pancreatic CancerMetastatic Pancreatic Cancer
AIO-Studien-gGmbH 151
Testing effectiveness (Phase 2)Looking for participantsNCT04592211
What this trial is testing

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer

Who this might be right for
Gastric Cancer Stage IV
Yonsei University 71
Large-scale testing (Phase 3)Study completedNCT02965378
What this trial is testing

Lung-MAP: AZD4547 as Second-Line Therapy in Treating FGFR Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
FGFR1 Gene AmplificationFGFR1 Gene MutationFGFR2 Gene Amplification+5 more
SWOG Cancer Research Network 43
Post-approval studies (Phase 4)Looking for participantsNCT06134284
What this trial is testing

Clinical Study of OR for Second-line Treatment of Refractory MZL

Who this might be right for
OR Regimen for Relapsed/Refractory Marginal Zone Lymphoma
Lixia Sheng 39
Testing effectiveness (Phase 2)UnknownNCT01492543
What this trial is testing

Study of TS-1 as 2nd Line Treatment in Patients With Advanced Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Chinese Academy of Medical Sciences 30
Testing effectiveness (Phase 2)UnknownNCT04734249
What this trial is testing

Second-line Surufatinib Combined With Chemotherapy in Advanced CRC

Who this might be right for
Advanced Colorectal Cancer
Fujian Cancer Hospital 56
Testing effectiveness (Phase 2)UnknownNCT01969955
What this trial is testing

Nab-paclitaxel as Second-line Therapy in Locally Advanced or Metastatic Squamous Lung Cancer

Who this might be right for
Squamous Cell Carcinoma of Lung
Chinese Academy of Medical Sciences 50
Large-scale testing (Phase 3)Looking for participantsNCT05978050
What this trial is testing

Nimotuzumab Combined With Paclitaxel for Recurrent Metastatic Gastric or Esophagogastric Junction Adenocarcinoma

Who this might be right for
Gastric or Esophagogastric Junction Adenocarcinoma
Biotech Pharmaceutical Co., Ltd. 354
Testing effectiveness (Phase 2)UnknownNCT00006115
What this trial is testing

Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group
Large-scale testing (Phase 3)UnknownNCT00197418
What this trial is testing

Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection

Who this might be right for
Helicobacter InfectionsGastritisGastric Ulcer+1 more
Hamamatsu University
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