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Results for “Selinexor”

187 trials

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Showing 20 of 187 results

Testing effectiveness (Phase 2)Study completedNCT02336815
What this trial is testing

Selinexor Treatment of Refractory Myeloma

Who this might be right for
Multiple Myeloma
Karyopharm Therapeutics Inc 202
Early research (Phase 1)Looking for participantsNCT07200102
What this trial is testing

Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma

Who this might be right for
Multiple Myeloma
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Looking for participantsNCT06559553
What this trial is testing

"Selinexor+Pegaspargase+Dexamethasone"in Ⅰ/Ⅱ NKTCL

Who this might be right for
NKTCLSelinexor
Mingzhi Zhang 50
Testing effectiveness (Phase 2)Looking for participantsNCT06517511
What this trial is testing

Selinexor in Combination With R-CHOP as the First-line Therapy for TP53-mutated DLBCL Patients (Smart Trial)

Who this might be right for
Diffuse Large B Cell Lymphoma
Sun Yat-sen University 42
Testing effectiveness (Phase 2)UnknownNCT04891744
What this trial is testing

Selinexor in Combination With Thalidomide and Dexamethasone in RRMM

Who this might be right for
Multiple Myeloma
Li Zheng 48
Testing effectiveness (Phase 2)Looking for participantsNCT05980806
What this trial is testing

Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

Who this might be right for
MyelofibrosisModerate ThrombocytopeniaMild Thrombocytopenia
Karyopharm Therapeutics Inc 58
Early research (Phase 1)UnknownNCT05201118
What this trial is testing

A Fully Human BCMA-targeting CAR (CT103A) Combined With Selinexor in Patients With Relapsed/Refractory Extramedullary Multiple Myeloma

Who this might be right for
Extramedullary Multiple Myeloma
Chunrui Li 20
Testing effectiveness (Phase 2)UnknownNCT05969158
What this trial is testing

Hetrombopag in Secondary Prevention of XPO-1 Inhibitor-induced Thrombocytopenia in Lymphoma

Who this might be right for
Chemotherapy-Induced Thrombocytopenia
Sun Yat-sen University 90
Early research (Phase 1)Study completedNCT02269293
What this trial is testing

Selective Inhibitor of Nuclear Export, Selinexor (KPT-330) in Combination With Paclitaxel and Carboplatin in Patients With Advanced Ovarian or Endometrial Cancers

Who this might be right for
Ovarian CancerEndometrial Cancer
Memorial Sloan Kettering Cancer Center 23
Early research (Phase 1)Study completedNCT01607892
What this trial is testing

Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced Hematological Cancer

Who this might be right for
Hematological Malignancies
Karyopharm Therapeutics Inc 286
Testing effectiveness (Phase 2)Looking for participantsNCT05833893
What this trial is testing

Clinical Study of XPO1 Inhibitor Selinexor Combined With COPL in Newly Diagnosed Advanced NK/T-cell Lymphoma

Who this might be right for
nk/T-cell LymphomaNewly DiagnosedAdvanced Lymphoma
Chinese PLA General Hospital 10
Testing effectiveness (Phase 2)Ended earlyNCT06449482
What this trial is testing

Selinexor、Venetoclax and Azactidine in the Treatment of ND AML Patients Who Are Not Eligible for Intense Chemotherapy

Who this might be right for
Acute Myeloid Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China 6
Not applicableLooking for participantsNCT06933277
What this trial is testing

Observational Study on the Combination of Selinexor With Bortezomib and Dexamethasone for the Treatment of MM Patients

Who this might be right for
Multiple Myeloma
Gruppo Italiano Malattie EMatologiche dell'Adulto 159
Testing effectiveness (Phase 2)Ended earlyNCT03095612
What this trial is testing

Phase 1/2 Trial of Selinexor (KPT-330) With Docetaxel for Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer
University of Texas Southwestern Medical Center 41
Early research (Phase 1)Ended earlyNCT02419495
What this trial is testing

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+26 more
M.D. Anderson Cancer Center 221
Large-scale testing (Phase 3)Looking for participantsNCT07011056
What this trial is testing

A Phase III Clinical Study of Purinostat Mesylate for Injection in Patients With Diffuse Large B-cell Lymphoma

Who this might be right for
Recurrent and Refractory Diffuse Large B-cell Lymphoma
Chengdu Zenitar Biomedical Technology Co., Ltd 390
Large-scale testing (Phase 3)Study completedNCT03110562
What this trial is testing

Bortezomib, Selinexor, and Dexamethasone in Patients With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Karyopharm Therapeutics Inc 402
Early research (Phase 1)Ended earlyNCT05093608
What this trial is testing

SELINEXOR in Combination w/Bevacizumab and Atezolizumab in Newly Diagnosed Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT04782687
What this trial is testing

Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma

Who this might be right for
Multiple MyelomaMyeloma MultipleKahler Disease+4 more
US Oncology Research 73
Large-scale testing (Phase 3)Active Not RecruitingNCT05028348
What this trial is testing

Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma

Who this might be right for
Multiple Myeloma
European Myeloma Network B.V. 117
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