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Results for “Selinexor”

183 trials

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Showing 20 of 183 results

Testing effectiveness (Phase 2)WithdrawnNCT05170789
What this trial is testing

Elotuzumab, Selinexor, and Dexamethasone for Relapsed Refractory Multiple Myeloma

Who this might be right for
Relapsed Multiple MyelomaRefractory Multiple Myeloma
Tulane University School of Medicine
Early research (Phase 1)Study completedNCT01896505
What this trial is testing

A Phase I Trial to Assess the Effects of Food and Formulation on PK of KPT-330 in Patients With Sarcoma

Who this might be right for
Sarcoma
Karyopharm Therapeutics Inc 54
Testing effectiveness (Phase 2)WithdrawnNCT02431351
What this trial is testing

Efficacy & Safety Study of KPT-330 in Erythropoietin-Refractory Lower-Risk Myelodysplastic Syndrome Patients

Who this might be right for
Myelodysplastic Syndrome
Karyopharm Therapeutics Inc
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Looking for participantsNCT05099003
What this trial is testing

The Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Who this might be right for
Malignant Glioma
National Cancer Institute (NCI) 132
Not applicableUnknownNCT05805072
What this trial is testing

Selinexor and HAAG With/Without HMA in Relapsed/Refractory Acute Leukemia (AML) Patients

Who this might be right for
Relapsed/Refractory AML
The First Affiliated Hospital of Soochow University 20
Early research (Phase 1)Study completedNCT02303392
What this trial is testing

Selinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggressive Non-Hodgkin Lymphoma

Who this might be right for
Prolymphocytic LeukemiaRecurrent Adult Diffuse Large Cell LymphomaRecurrent Mantle Cell Lymphoma+2 more
Jennifer Woyach 34
Testing effectiveness (Phase 2)WithdrawnNCT05177276
What this trial is testing

Selinexor Combination Ph 1 Study

Who this might be right for
Solid Tumor Malignancy
Martin Gutierrez
Early research (Phase 1)Looking for participantsNCT06225310
What this trial is testing

A Trial of Selinexor, Ruxolitinib and Methylprednisolone

Who this might be right for
Multiple Myeloma in RelapseMultiple Myeloma, Refractory
Oncotherapeutics 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT07437170
What this trial is testing

Selinexor Combined With Induction Chemotherapy for Children With NUP98-positive AML

Who this might be right for
Acute Myeloid LeukemiaPediatric Acute Myeloid LeukemiaNUP98 Fusion-positive Acute Myeloid Leukemia
The Children's Hospital of Zhejiang University School of Medicine 10
Large-scale testing (Phase 3)Study completedNCT03110562
What this trial is testing

Bortezomib, Selinexor, and Dexamethasone in Patients With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Karyopharm Therapeutics Inc 402
Early research (Phase 1)Study completedNCT03661515
What this trial is testing

Selinexor (KPT-330) Plus FLAG-Ida for the Treatment of Relapsing/Refractory AML

Who this might be right for
Acute Myeloid Leukemia
PETHEMA Foundation 16
Testing effectiveness (Phase 2)Ended earlyNCT04421378
What this trial is testing

Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Karyopharm Therapeutics Inc 74
Early research (Phase 1)Study completedNCT02199665
What this trial is testing

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Who this might be right for
Refractory Multiple Myeloma
University of Chicago 52
Early research (Phase 1)Study completedNCT04640779
What this trial is testing

Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma

Who this might be right for
Recurrent Histiocytic and Dendritic Cell NeoplasmRecurrent Hodgkin LymphomaRecurrent Non-Hodgkin Lymphoma+5 more
Mayo Clinic 22
Early research (Phase 1)Study completedNCT01607892
What this trial is testing

Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced Hematological Cancer

Who this might be right for
Hematological Malignancies
Karyopharm Therapeutics Inc 286
Not applicableNo Longer AvailableNCT03850704
What this trial is testing

Single Patient Use of Selinexor and Dexamethasone for a Patient With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Masonic Cancer Center, University of Minnesota
Early research (Phase 1)Study completedNCT04811196
What this trial is testing

Different Dosing Schedules of Selinexor in Sarcoma Patients

Who this might be right for
Soft Tissue SarcomaMalignant Peripheral Nerve Sheath Tumor (MPNST)Leiomyosarcoma+1 more
University Health Network, Toronto 56
Not applicableActive Not RecruitingNCT06452446
What this trial is testing

Telehealth-based Symptom Management for Veterans Treated With Selinexor

Who this might be right for
Multiple MyelomaLarge-cell Lymphoma
Durham VA Medical Center 20
Testing effectiveness (Phase 2)Looking for participantsNCT06966154
What this trial is testing

A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL

Who this might be right for
Natural Killer/T-cell LymphomaRelapsed or Refractory Lymphoma Including ENKL
Fudan University 68
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