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Results for “Severe Aplastic Anemia, Refractory”

53 trials

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Showing 20 of 53 results

Testing effectiveness (Phase 2)WithdrawnNCT05323617
What this trial is testing

Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive Therapy

Who this might be right for
Severe Aplastic Anemia (SAA)
Amgen
Testing effectiveness (Phase 2)Study completedNCT00003336
What this trial is testing

Pilot Study Of Unrelated UCB Transplant for Non-Malignant Hematologic Conditions

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Case Comprehensive Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT03988608
What this trial is testing

Study Assessed the Safety and Efficacy of Eltrombopag in Chinese Refractory or Relapsed Severe Aplastic Anemia (SAA) Subjects.

Who this might be right for
Aplastic Anemia
Novartis Pharmaceuticals 20
Not applicableUnknownNCT00295997
What this trial is testing

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia

Who this might be right for
Chronic Myeloproliferative DisordersKidney CancerLeukemia+4 more
University of California, San Francisco 35
Not applicableStudy completedNCT00856388
What this trial is testing

Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+97 more
Roswell Park Cancer Institute 62
Not applicableStudy completedNCT00244010
What this trial is testing

Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias

Who this might be right for
Anemia, AplasticAmegakaryocytic ThrombocytopeniaDiamond-Blackfan Anemia+1 more
St. Jude Children's Research Hospital 4
Testing effectiveness (Phase 2)Looking for participantsNCT02143830
What this trial is testing

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

Who this might be right for
Fanconi AnemiaSevere Marrow FailureMyelodysplastic Syndrome (MDS)+1 more
Children's Hospital Medical Center, Cincinnati 70
Testing effectiveness (Phase 2)Study completedNCT01297972
What this trial is testing

Mesenchymal Stem Cells in the Treatment of Relapsed/Refractory Severe Acquired Aplastic Anemia

Who this might be right for
Aplastic Anemia
University of Sao Paulo 9
Testing effectiveness (Phase 2)Study completedNCT00006379
What this trial is testing

Non-Ablative Allo HSCT For Hematologic Malignancies or SAA

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+5 more
Case Comprehensive Cancer Center 58
Testing effectiveness (Phase 2)Study completedNCT01529827
What this trial is testing

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+75 more
Roswell Park Cancer Institute 94
Testing effectiveness (Phase 2)Ended earlyNCT03333486
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more
Roswell Park Cancer Institute 31
Testing effectiveness (Phase 2)Study completedNCT02148133
What this trial is testing

Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic Anemia

Who this might be right for
Cytopaenia
Novartis Pharmaceuticals 21
Very early researchEnded earlyNCT00212407
What this trial is testing

New York Blood Center National Cord Blood Program

Who this might be right for
LeukemiaLymphomaGenetic Disease+2 more
New York Blood Center 4,476
Testing effectiveness (Phase 2)Active Not RecruitingNCT05998408
What this trial is testing

JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure

Who this might be right for
Severe Aplastic AnemiaSingle Lineage Cytopenias, T-LGLHypoplastic MDS
National Heart, Lung, and Blood Institute (NHLBI) 13
Not applicableEnded earlyNCT00290628
What this trial is testing

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersDiamond-blackfan AnemiaFanconi Anemia+6 more
Masonic Cancer Center, University of Minnesota 43
Not applicableEnded earlyNCT00952185
What this trial is testing

Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+7 more
City of Hope Medical Center 9
Testing effectiveness (Phase 2)Looking for participantsNCT01174108
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

Who this might be right for
Severe Aplastic AnemiaMDS (Myelodysplastic Syndrome)
National Heart, Lung, and Blood Institute (NHLBI) 120
Post-approval studies (Phase 4)UnknownNCT06426043
What this trial is testing

A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag

Who this might be right for
Aplastic Anemia
Peking Union Medical College Hospital 40
Testing effectiveness (Phase 2)Study completedNCT03025698
What this trial is testing

A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic Anemia

Who this might be right for
Aplastic Anemia
Novartis Pharmaceuticals 51
Early research (Phase 1)Looking for participantsNCT06622694
What this trial is testing

CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia

Who this might be right for
Severe Aplastic AnemiaRelapseRefractory+1 more
Institute of Hematology & Blood Diseases Hospital, China 15
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