Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe Combined Immune Deficiency”

117 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 117 results

Not applicableStudy completedNCT00000703
What this trial is testing

Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members

Who this might be right for
Lymphoma, Non-HodgkinHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 45
Testing effectiveness (Phase 2)Study completedNCT04996797
What this trial is testing

Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Who this might be right for
Ulcerative Colitis
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 178
Not applicableAvailableNCT06731036
What this trial is testing

Expanded Access to CD34+ Selection Utilizing Miltenyi CliniMACS Prodigy® for Patients Receiving Peripheral Blood Stem Cell Transplantations and Stem Cell Boosts

Who this might be right for
Severe Combined ImmunodeficiencyFanconi AnemiaDyskeratosis Congenita+1 more
University of Florida
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT03619551
What this trial is testing

Conditioning SCID Infants Diagnosed Early

Who this might be right for
SCID
Center for International Blood and Marrow Transplant Research 56
Early research (Phase 1)UnknownNCT03601286
What this trial is testing

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency, X-Linked
Great Ormond Street Hospital for Children NHS Foundation Trust 5
Not applicableUnknownNCT05300334
What this trial is testing

Investigation of ADA Enzyme Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 800
Testing effectiveness (Phase 2)UnknownNCT03315078
What this trial is testing

Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency

Who this might be right for
X-Linked Combined Immunodeficiency Diseases
National Institute of Allergy and Infectious Diseases (NIAID) 13
Testing effectiveness (Phase 2)Study completedNCT01279720
What this trial is testing

Gene Therapy ADA Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 8
Testing effectiveness (Phase 2)Ended earlyNCT00490100
What this trial is testing

Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1

Who this might be right for
Growth FailureX-linked Severe Combined Immunodeficiency (XSCID)Growth Hormone Resistence
National Institute of Allergy and Infectious Diseases (NIAID) 6
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
Not applicableEnrolling By InvitationNCT01186913
What this trial is testing

Natural History Study of SCID Disorders

Who this might be right for
Severe Combined Immunodeficiency (SCID)Leaky SCIDOmenn Syndrome+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 690
Testing effectiveness (Phase 2)Study completedNCT02999984
What this trial is testing

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
University of California, Los Angeles 10
Large-scale testing (Phase 3)Study completedNCT01019876
What this trial is testing

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

Who this might be right for
Bone Marrow FailureOsteopetrosisFanconi Anemia+1 more
Columbia University 38
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableEnrolling By InvitationNCT00895271
What this trial is testing

Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders

Who this might be right for
Primary ImmunodeficiencyDOCK8Virus Susceptibility
National Institute of Allergy and Infectious Diseases (NIAID) 200
Testing effectiveness (Phase 2)Study completedNCT03879876
What this trial is testing

Safety and Efficacy Study of Human T Lymphoid Progenitor (HTLP) Injection After Partially HLA Compatible Allogeneic Hematopoietic Stem Cell Transplantation in SCID Patients

Who this might be right for
Pediatric PatientsAny Type of Severe Combined Immunodeficiency (SCID)Partial HLA Incompatible Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Assistance Publique - Hôpitaux de Paris 4
Not applicableWithdrawnNCT01182857
What this trial is testing

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

Who this might be right for
ADA-SCID
National Human Genome Research Institute (NHGRI)
Early research (Phase 1)Study completedNCT01586455
What this trial is testing

Human Placental-Derived Stem Cell Transplantation

Who this might be right for
Mucopolysaccharidosis IMucopolysaccharidosis VIAdrenoleukodystrophy+13 more
New York Medical College 43
Next Page