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Results for “Severe Combined Immunodeficiency”

116 trials

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Showing 20 of 116 results

Not applicableLooking for participantsNCT00055172
What this trial is testing

Genetic Basis of Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency
National Heart, Lung, and Blood Institute (NHLBI) 100
Testing effectiveness (Phase 2)WithdrawnNCT05545319
What this trial is testing

Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19

Who this might be right for
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Coronavirus Disease 2019 (COVID-19)Immunocompromised+2 more
Pfizer
Large-scale testing (Phase 3)Study completedNCT00001014
What this trial is testing

Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

Who this might be right for
Pneumonia, Pneumocystis CariniiHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 302
Not applicableUnknownNCT01175239
What this trial is testing

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)

Who this might be right for
X-linked Severe Combined Immunodeficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 1
Not applicableEnrolling By InvitationNCT03478670
What this trial is testing

Strimvelis Registry Study to Follow-up Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID)

Who this might be right for
Immunologic Deficiency Syndromes
Fondazione Telethon 50
Not applicableStudy completedNCT00001255
What this trial is testing

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 10
Not applicableLooking for participantsNCT03645460
What this trial is testing

Gene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)

Who this might be right for
Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)
Shenzhen Geno-Immune Medical Institute 10
Not applicableUnknownNCT00596999
What this trial is testing

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

Who this might be right for
Hematologic Malignancies
Celgene Corporation 6
Not applicableStudy completedNCT00043225
What this trial is testing

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Who this might be right for
Psuedomas InfectionCystic Fibrosis
National Heart, Lung, and Blood Institute (NHLBI) 76
Early research (Phase 1)Study completedNCT00008450
What this trial is testing

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Who this might be right for
Adenosine Deaminase DeficiencyAutosomal Recessive DisorderImmune System Disorder+4 more
Fred Hutchinson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT04996797
What this trial is testing

Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Who this might be right for
Ulcerative Colitis
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 178
Not applicableUnknownNCT04172181
What this trial is testing

Multi-center Clinical Study of Cord Blood Stem Cell Transplantation for SCID

Who this might be right for
Severe Combined Immunodeficiency Disease
Children's Hospital of Fudan University 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT01821781
What this trial is testing

Immune Disorder HSCT Protocol

Who this might be right for
Immune Deficiency DisordersSevere Combined ImmunodeficiencyChronic Granulomatous Disease+11 more
Washington University School of Medicine 20
Post-approval studies (Phase 4)Study completedNCT01695798
What this trial is testing

IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi.

Who this might be right for
Immunity to Polio Vaccines in Malnourished InfantsImmunity to Polio Vaccines in Non-malnourished Infants
Aga Khan University 840
Not applicableStudy completedNCT00006335
What this trial is testing

Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 40
Not applicableLooking for participantsNCT06659588
What this trial is testing

Study of Populations at Risk of Developing Chronic Hepatitis Linked to Chronic Enteric Virus Infection in Patients With Primary Immunodeficiency and Secondary Humoral Deficiency

Who this might be right for
Humoral Primary Immunodeficiencies (PIDs)Secondary Form of Humoral ImmunodeficienciesCombined Immunodeficiency (CID)+1 more
Assistance Publique - Hôpitaux de Paris 120
Testing effectiveness (Phase 2)Study completedNCT01193842
What this trial is testing

Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas

Who this might be right for
AIDS-Related Plasmablastic LymphomaAIDS-Related Primary Effusion LymphomaAnn Arbor Stage I Diffuse Large B-Cell Lymphoma+13 more
National Cancer Institute (NCI) 107
Testing effectiveness (Phase 2)Ended earlyNCT01182675
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim

Who this might be right for
Severe Combined Immunodeficiency
University of California, San Francisco 7
Testing effectiveness (Phase 2)Looking for participantsNCT01306019
What this trial is testing

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

Who this might be right for
X-linked Severe Combined Immunodeficiency (XSCID)
National Institute of Allergy and Infectious Diseases (NIAID) 40
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
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