Early research (Phase 1)Study completedNCT01565902What this trial is testingPharmacokinetics of BAF312 in Patients With Hepatic ImpairmentWho this might be right forHepatic Impairment Novartis Pharmaceuticals 40
Early research (Phase 1)Study completedNCT06908954What this trial is testingThe Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single DoseWho this might be right forHepatic ImpairmentHealthy Ipsen 31
Post-approval studies (Phase 4)Ended earlyNCT03818672What this trial is testingSteady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired SubjectsWho this might be right forSevere Hepatic Impairment Bausch Health Americas, Inc. 5
Early research (Phase 1)Study completedNCT03865446What this trial is testingEvaluate Severe Hepatic Impairment on Dacomitinib PKWho this might be right forSevere Hepatic Impairment Pfizer 16
Early research (Phase 1)Study completedNCT01767623What this trial is testingThe Impact of Severe Hepatic Impairment on the Pharmacokinetics and Safety of Vemurafenib in BRAF V600 Mutation-Positive Cancer ParticipantsWho this might be right forNeoplasms Hoffmann-La Roche 8
Early research (Phase 1)Study completedNCT03824678What this trial is testingEvaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy SubjectsWho this might be right forHepatic ImpairmentHealthy Volunteers Celgene 40
Early research (Phase 1)Study completedNCT01727128What this trial is testingPharmacokinetic Study of BKM120 in Subjects With Hepatic ImpairmentWho this might be right forHepatic Impairment Novartis Pharmaceuticals 31
Post-approval studies (Phase 4)Study completedNCT01846455What this trial is testingSingle Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired SubjectsWho this might be right forHepatic FailureHepatic ImpairmentChronic Hepatitis C Infection With Hepatic Coma Indivior Inc. 43
Early research (Phase 1)Study completedNCT01764776What this trial is testingEffect of Hepatic Impairment on LDE225..Who this might be right forNormal Hepatic FunctionImpaired Hepatic Function Novartis Pharmaceuticals 33
Early research (Phase 1)Study completedNCT04634149What this trial is testingEvaluate the Drug Levels, Safety, and Tolerability of BMS-986036 in Participants With Normal Liver Function and Participants With Moderate and Severe Liver ImpairmentWho this might be right forModerate Liver ImpairmentSevere Liver Impairment Bristol-Myers Squibb 16
Early research (Phase 1)Looking for participantsNCT07546760What this trial is testingA Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234Who this might be right forHepatic Impairment AstraZeneca 28
Early research (Phase 1)Study completedNCT06911320What this trial is testingStudy of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic FunctionWho this might be right forHealthy Volunteer StudyHepatic ImpairmentRenal Impairment Atea Pharmaceuticals, Inc. 28
Early research (Phase 1)Looking for participantsNCT07231991What this trial is testingLearn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver FunctionWho this might be right forHealthy Participants Pfizer 24
Early research (Phase 1)Study completedNCT03968848What this trial is testingInvestigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its MetaboliteWho this might be right forHepatic ImpairmentHepatic InsufficiencyHealthy Subjects Acerta Pharma BV 16
Early research (Phase 1)Study completedNCT02210871What this trial is testingInvestigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic FunctionWho this might be right forDiabetesDiabetes Mellitus, Type 2Hepatic Impaired Novo Nordisk A/S 44
Early research (Phase 1)Study completedNCT01456663What this trial is testingEvaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy SubjectsWho this might be right forHepatic Impairment Novartis Pharmaceuticals 118
Early research (Phase 1)Study completedNCT07018492What this trial is testingPhase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy ControlsWho this might be right forHepatic Impairment Shionogi 32
Early research (Phase 1)Study completedNCT07198087What this trial is testingInvestigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy ParticipantsWho this might be right forPrimary Central Nervous System Lymphoma (PCNSL) Ono Pharmaceutical Co., Ltd. 40
Testing effectiveness (Phase 2)Looking for participantsNCT06682988What this trial is testingAssess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab SoravtansineWho this might be right forAdvanced High-Grade Epithelial Ovarian CancerPrimary Peritoneal CancerFallopian Tube Cancers AbbVie 110
Early research (Phase 1)Study completedNCT04867941What this trial is testingEvaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196Who this might be right forHepatic Insufficiency Acerta Pharma BV 18