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Results for “Severe Hypertriglyceridemia”

49 trials

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Showing 20 of 49 results

Testing effectiveness (Phase 2)Study completedNCT02250105
What this trial is testing

Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia

Who this might be right for
Hypertriglyceridemia
Arisaph Pharmaceuticals Inc 80
Not applicableApproved For MarketingNCT06500598
What this trial is testing

Compassionate Use of Evinacumab

Who this might be right for
Pediatric Homozygous Familial Hypercholesterolemia (HoFH)Severe Hypertriglyceridemia (HTG)Dysbetalipoproteinemia (DBL)
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT07308392
What this trial is testing

Phase II Clinical Trial Evaluating the Efficacy and Safety of HRS-7249 and SHR-1918 in Patients With Severe Hypertriglyceridemia at High Risk of Acute Pancreatitis

Who this might be right for
Severe Hypertriglyceridemia With a High Risk of Acute Pancreatitis
Fujian Shengdi Pharmaceutical Co., Ltd. 108
Post-approval studies (Phase 4)UnknownNCT03501680
What this trial is testing

Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis.

Who this might be right for
Acute PancreatitisHypertriglyceridemia
First Affiliated Hospital of Wenzhou Medical University 200
Large-scale testing (Phase 3)Study completedNCT03398005
What this trial is testing

CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1)

Who this might be right for
Hypertriglyceridemia
Grace Therapeutics Inc. 256
Testing effectiveness (Phase 2)Study completedNCT01146522
What this trial is testing

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hyperlipoproteinemia
Novartis Pharmaceuticals 8
Large-scale testing (Phase 3)UnknownNCT02625870
What this trial is testing

Omega-3-Acid Ethyl Esters 90 Soft Capsules for Lowering Very High Triglycerides

Who this might be right for
Hypertriglyceridemia
Jiangsu HengRui Medicine Co., Ltd. 240
Large-scale testing (Phase 3)Study completedNCT02009865
What this trial is testing

Epanova® for Lowering Very High Triglycerides II (EVOLVE II)

Who this might be right for
Hypertriglyceridemia
AstraZeneca 379
Large-scale testing (Phase 3)Study completedNCT03361501
What this trial is testing

CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2)

Who this might be right for
Hypertriglyceridemia
Grace Therapeutics Inc. 278
Large-scale testing (Phase 3)Study completedNCT05610280
What this trial is testing

Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Who this might be right for
HypertriglyceridemiaCardiovascular DiseasesAtherosclerosis
Ionis Pharmaceuticals, Inc. 1,478
Testing effectiveness (Phase 2)Looking for participantsNCT07604974
What this trial is testing

Assess the Safety, Tolerability and Efficacy of ION775

Who this might be right for
HypertriglyceridemiaSevere Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 72
Large-scale testing (Phase 3)UnknownNCT01229566
What this trial is testing

Efficacy Study to Treat Subjects With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Trygg Pharma, Inc. 240
Testing effectiveness (Phase 2)Study completedNCT01594983
What this trial is testing

A Pilot Study to Assess the Efficacy and Safety of LCQ908 Alone and in Combination With Fenofibrate or Lovaza® in Patients With Severe Hypertriglyceridemia

Who this might be right for
Non Familial Chylocmicronemia Syndrome (Non-FCS)
Novartis Pharmaceuticals 58
Testing effectiveness (Phase 2)Study completedNCT04541186
What this trial is testing

Study to Explore the Efficacy and Safety of BIO89-100 (Pegozafermin) in Participants With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
89bio, Inc. 86
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Large-scale testing (Phase 3)Active Not RecruitingNCT06548100
What this trial is testing

The Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 9
Testing effectiveness (Phase 2)Ended earlyNCT04863014
What this trial is testing

Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis

Who this might be right for
Hypertriglyceridemia
Regeneron Pharmaceuticals 21
Testing effectiveness (Phase 2)Study completedNCT03452228
What this trial is testing

Safety and Efficacy Following Repeat-Dose of Evinacumab (Anti-ANGPTL3) in Patients With Severe Hypertriglyceridemia (sHTG) at Risk for Acute Pancreatitis

Who this might be right for
Severe Hypertriglyceridemia (sHTG)
Regeneron Pharmaceuticals 52
Testing effectiveness (Phase 2)Study completedNCT02944383
What this trial is testing

A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia

Who this might be right for
Severe HypertriglyceridemiaMixed Dyslipidaemia
NeuroBo Pharmaceuticals Inc. 91
Not applicableStudy completedNCT02622854
What this trial is testing

Plasma Exchange vs Conservative Management in Non-severe Acute Hypertriglyceridemic Pancreatitis

Who this might be right for
Acute Pancreatitis
University Medical Centre Ljubljana 22
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