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Results for “Severe Hypertriglyceridemia”

48 trials

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Showing 20 of 48 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06548100
What this trial is testing

The Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 9
Testing effectiveness (Phase 2)Study completedNCT05355402
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

Who this might be right for
HypertriglyceridemiaAtherosclerotic Cardiovascular DiseaseSevere Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 154
Large-scale testing (Phase 3)Study completedNCT04239950
What this trial is testing

Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hypertriglyceridemia
Mochida Pharmaceutical Company, Ltd. 316
Large-scale testing (Phase 3)Looking for participantsNCT06880770
What this trial is testing

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

Who this might be right for
Severe Hypertriglyceridemia
Arrowhead Pharmaceuticals 288
Large-scale testing (Phase 3)Study completedNCT05610280
What this trial is testing

Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Who this might be right for
HypertriglyceridemiaCardiovascular DiseasesAtherosclerosis
Ionis Pharmaceuticals, Inc. 1,478
Large-scale testing (Phase 3)Active Not RecruitingNCT05852431
What this trial is testing

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
89bio, Inc. 360
Large-scale testing (Phase 3)Study completedNCT03011450
What this trial is testing

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Who this might be right for
Severe Hypertriglyceridemia
Kowa Research Institute, Inc. 471
Testing effectiveness (Phase 2)Study completedNCT01146522
What this trial is testing

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hyperlipoproteinemia
Novartis Pharmaceuticals 8
Large-scale testing (Phase 3)Study completedNCT01242527
What this trial is testing

Epanova® for Lowering Very High Triglycerides

Who this might be right for
Severe Hypertriglyceridemia
AstraZeneca 399
Testing effectiveness (Phase 2)Study completedNCT01208961
What this trial is testing

Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, Evaluation

Who this might be right for
Severe Hypertriglyceridemia
AstraZeneca 54
Testing effectiveness (Phase 2)Study completedNCT02250105
What this trial is testing

Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia

Who this might be right for
Hypertriglyceridemia
Arisaph Pharmaceuticals Inc 80
Testing effectiveness (Phase 2)Study completedNCT04720534
What this trial is testing

Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Arrowhead Pharmaceuticals 229
Not applicableLooking for participantsNCT03087253
What this trial is testing

The LD Lync Study - Natural History Study of Lipodystrophy Syndromes

Who this might be right for
Lipodystrophy (Genetic or Acquired, Non HIV)
University of Michigan 500
Not applicableUnknownNCT02858102
What this trial is testing

Impact of Aerobic Exercise on Metabolic Syndrome, Neurocognition and Empowerment in Individuals With Mental Disorders

Who this might be right for
Metabolic SyndromeMental Disorders
Fundación Marques de Valdecilla 50
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT07269210
What this trial is testing

Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Eli Lilly and Company 60
Testing effectiveness (Phase 2)Study completedNCT02944383
What this trial is testing

A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia

Who this might be right for
Severe HypertriglyceridemiaMixed Dyslipidaemia
NeuroBo Pharmaceuticals Inc. 91
Large-scale testing (Phase 3)Study completedNCT05079919
What this trial is testing

Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 617
Testing effectiveness (Phase 2)Study completedNCT06555640
What this trial is testing

A Phase II Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Zhejiang Doer Biologics Co., Ltd. 79
Large-scale testing (Phase 3)WithdrawnNCT04662528
What this trial is testing

Safety and Efficacy of MAT9001(Omega-3-pentaenoic Acid) in Subjects With Triglycerides ≥500 mg/dL and <2000 mg/dL

Who this might be right for
Severe Hypertriglyceridemia
Matinas Biopharma, Inc
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