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Results for “Severe Hypertriglyceridemia”

52 trials

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Showing 20 of 52 results

Not applicableStudy completedNCT02622854
What this trial is testing

Plasma Exchange vs Conservative Management in Non-severe Acute Hypertriglyceridemic Pancreatitis

Who this might be right for
Acute Pancreatitis
University Medical Centre Ljubljana 22
Early research (Phase 1)Study completedNCT03783377
What this trial is testing

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
HypertriglyceridemiaFamilial Chylomicronemia
Arrowhead Pharmaceuticals 112
Testing effectiveness (Phase 2)Ended earlyNCT04863014
What this trial is testing

Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis

Who this might be right for
Hypertriglyceridemia
Regeneron Pharmaceuticals 21
Testing effectiveness (Phase 2)Study completedNCT01968720
What this trial is testing

Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia

Who this might be right for
HyperlipidemiasHypertriglyceridemiaDyslipidemias+2 more
Catabasis Pharmaceuticals 16
Large-scale testing (Phase 3)Study completedNCT03398005
What this trial is testing

CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1)

Who this might be right for
Hypertriglyceridemia
Grace Therapeutics Inc. 256
Testing effectiveness (Phase 2)Study completedNCT01529424
What this trial is testing

Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia

Who this might be right for
Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 89
Large-scale testing (Phase 3)Study completedNCT03361501
What this trial is testing

CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2)

Who this might be right for
Hypertriglyceridemia
Grace Therapeutics Inc. 278
Not applicableUnknownNCT05883865
What this trial is testing

Safety Study of Fenofibrate During Pregnancy

Who this might be right for
Severe Hypertriglyceridemia During Pregnancy
First People's Hospital of Hangzhou 250
Early research (Phase 1)Study completedNCT02189252
What this trial is testing

An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis

Who this might be right for
Severe Hypertriglyceridemia
AstraZeneca 30
Not applicableLooking for participantsNCT03087253
What this trial is testing

The LD Lync Study - Natural History Study of Lipodystrophy Syndromes

Who this might be right for
Lipodystrophy (Genetic or Acquired, Non HIV)
University of Michigan 500
Testing effectiveness (Phase 2)Study completedNCT05355402
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

Who this might be right for
HypertriglyceridemiaAtherosclerotic Cardiovascular DiseaseSevere Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 154
Post-approval studies (Phase 4)UnknownNCT03501680
What this trial is testing

Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis.

Who this might be right for
Acute PancreatitisHypertriglyceridemia
First Affiliated Hospital of Wenzhou Medical University 200
Not applicableStudy completedNCT04223908
What this trial is testing

InFocus France Epidemiological Study of Health Burden in Major Hypertriglyceridemia

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
New French Society of Atherosclerosis 52
Large-scale testing (Phase 3)Study completedNCT05552326
What this trial is testing

Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 446
Large-scale testing (Phase 3)Study completedNCT02009865
What this trial is testing

Epanova® for Lowering Very High Triglycerides II (EVOLVE II)

Who this might be right for
Hypertriglyceridemia
AstraZeneca 379
Large-scale testing (Phase 3)WithdrawnNCT04662528
What this trial is testing

Safety and Efficacy of MAT9001(Omega-3-pentaenoic Acid) in Subjects With Triglycerides ≥500 mg/dL and <2000 mg/dL

Who this might be right for
Severe Hypertriglyceridemia
Matinas Biopharma, Inc
Very early researchLooking for participantsNCT07176923
What this trial is testing

CS-121 APOC3 Base Editing in FCS

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
CorrectSequence Therapeutics Co., Ltd 15
Large-scale testing (Phase 3)Active Not RecruitingNCT06347003
What this trial is testing

Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Arrowhead Pharmaceuticals 446
Not applicableApproved For MarketingNCT06500598
What this trial is testing

Compassionate Use of Evinacumab

Who this might be right for
Pediatric Homozygous Familial Hypercholesterolemia (HoFH)Severe Hypertriglyceridemia (HTG)Dysbetalipoproteinemia (DBL)
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT07269210
What this trial is testing

Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Eli Lilly and Company 60
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