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Results for “Severe Knee Osteoarthritis”

135 trials

Showing 20 of 135 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06865079
What this trial is testing

53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis (OA) of the Knee
OrthoTrophix, Inc 270
Early research (Phase 1)Study completedNCT04229225
What this trial is testing

Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Knee Osteoarthritis
Unity Biotechnology, Inc. 35
Large-scale testing (Phase 3)Study completedNCT00486811
What this trial is testing

Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Who this might be right for
PainKnee Osteoarthritis
Grünenthal GmbH 990
Large-scale testing (Phase 3)Study completedNCT05377489
What this trial is testing

Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
Grünenthal GmbH 714
Large-scale testing (Phase 3)Study completedNCT00345787
What this trial is testing

Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Osteoarthritic Pain

Who this might be right for
PainOsteoarthritis
Mundipharma K.K. 262
Not applicableStudy completedNCT00277186
What this trial is testing

Alberta Hip and Knee Replacement Project

Who this might be right for
Arthroplasty, Replacement, HipArthroplasty, Replacement, Knee
Alberta Bone and Joint Health Institute 3,434
Not applicableStudy completedNCT06134115
What this trial is testing

LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4

Who this might be right for
Primary Knee Osteoarthritis Grade 3 - 4
Pharmanutra S.p.a. 60
Not applicableStudy completedNCT06664905
What this trial is testing

Resistance Exercise in Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Valencia 28
Early research (Phase 1)Study completedNCT00454298
What this trial is testing

Study Evaluating AGG-523 in Subjects With Severe Osteoarthritis Requiring Total Knee Replacement

Who this might be right for
Osteoarthritis
Wyeth is now a wholly owned subsidiary of Pfizer 2
Testing effectiveness (Phase 2)Study completedNCT01709214
What this trial is testing

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

Who this might be right for
Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
Tris Pharma, Inc. 619
Not applicableStudy completedNCT05972525
What this trial is testing

What Matters to Patients With Severe Hip or Knee Osteoarthritis?

Who this might be right for
Hip OsteoarthritisKnee Osteoarthritis
Vejle Hospital 615
Not applicableUnknownNCT03902340
What this trial is testing

Comparison of the Efficacy, Tolerability and Safety of actiTENS to Those of Level 2 Analgesic Treatments.

Who this might be right for
Knee Osteoarthritis
Sublimed 110
Not applicableStudy completedNCT05274932
What this trial is testing

Exercise With Blood Flow Restriction in Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Valencia 22
Testing effectiveness (Phase 2)Study completedNCT03028870
What this trial is testing

Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee

Who this might be right for
Osteo Arthritis Knee
Purdue Pharma LP 291
Post-approval studies (Phase 4)UnknownNCT03090698
What this trial is testing

Outcomes of Injections in Patients Waiting for Total Knee Replacement

Who this might be right for
Osteoarthritis of the Knee
Universidade Federal Fluminense 120
Testing effectiveness (Phase 2)Study completedNCT01619839
What this trial is testing

Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain

Who this might be right for
Osteoarthritis of the Knee
Nektar Therapeutics 296
Large-scale testing (Phase 3)Study completedNCT00313846
What this trial is testing

Safety and Efficacy of Buprenorphine Transdermal System in Subjects With Moderate to Severe Osteoarthritis of Hip or Knee

Who this might be right for
Osteoarthritis
Purdue Pharma LP 529
Testing effectiveness (Phase 2)Study completedNCT00667654
What this trial is testing

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Who this might be right for
Osteoarthritis of the Knee
Centrexion Therapeutics 54
Not applicableStudy completedNCT03100799
What this trial is testing

An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, Knee
Unity Biotechnology, Inc. 30
Testing effectiveness (Phase 2)Study completedNCT00394563
What this trial is testing

A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee Pain

Who this might be right for
Osteoarthritis
Pfizer 450
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