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Results for “Severe Knee Osteoarthritis”

133 trials

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Showing 20 of 133 results

Not applicableStudy completedNCT00277186
What this trial is testing

Alberta Hip and Knee Replacement Project

Who this might be right for
Arthroplasty, Replacement, HipArthroplasty, Replacement, Knee
Alberta Bone and Joint Health Institute 3,434
Testing effectiveness (Phase 2)Study completedNCT00979953
What this trial is testing

Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis of the Knee
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 408
Testing effectiveness (Phase 2)Ended earlyNCT05838742
What this trial is testing

A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis (OA) Pain

Who this might be right for
PainOsteoarthritis, Knee
GlaxoSmithKline 314
Not applicableStudy completedNCT06664905
What this trial is testing

Resistance Exercise in Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Valencia 28
Early research (Phase 1)Study completedNCT04229225
What this trial is testing

Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Knee Osteoarthritis
Unity Biotechnology, Inc. 35
Large-scale testing (Phase 3)WithdrawnNCT04044742
What this trial is testing

Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, KneeKnee Pain Chronic
Sorrento Therapeutics, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT02847702
What this trial is testing

Evaluate the Analgesic Efficacy and Safety of VM902A in Subjects With Osteoarthritis (OA) of the Knee

Who this might be right for
Osteoarthritis Pain of the Knee
Purdue Pharma LP 75
Testing effectiveness (Phase 2)Study completedNCT01733186
What this trial is testing

Evaluation of Safety and Exploratory Efficacy of CARTISTEM®, a Cell Therapy Product for Articular Cartilage Defects

Who this might be right for
Degeneration Articular Cartilage Knee
Medipost, Inc. 12
Not applicableNot Yet RecruitingNCT06767787
What this trial is testing

Morbid Obesity and Severe Knee Osteoarthritis - Which Should Be Treated First?

Who this might be right for
Osteoarthritis of KneeArthroplasties, Knee ReplacementSleeve Gastrectomy
Memorial University of Newfoundland 142
Large-scale testing (Phase 3)Study completedNCT00980798
What this trial is testing

Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee

Who this might be right for
PainOsteoarthritis, HipOsteoarthritis, Knee
Janssen-Cilag International NV 288
Not applicableUnknownNCT04006314
What this trial is testing

Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Chang Gung Memorial Hospital 24
Testing effectiveness (Phase 2)Study completedNCT01619839
What this trial is testing

Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain

Who this might be right for
Osteoarthritis of the Knee
Nektar Therapeutics 296
Large-scale testing (Phase 3)Study completedNCT00420992
What this trial is testing

Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Who this might be right for
OsteoarthritisChronic Pain
Pfizer 547
Testing effectiveness (Phase 2)Study completedNCT04129944
What this trial is testing

Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, Knee
Unity Biotechnology, Inc. 183
Not applicableStudy completedNCT00435292
What this trial is testing

Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
Primus Pharmaceuticals 350
Post-approval studies (Phase 4)Study completedNCT05936762
What this trial is testing

Clinical Efficacy and Safety of NEOIAL HC for Intra-articular Use in the Treatment of Severe Knee Osteoarthritis

Who this might be right for
Osteoarthritis of Knee
Nextrasearch S.r.l.s. 15
Not applicableActive Not RecruitingNCT05112926
What this trial is testing

Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Miami 9
Not applicableActive Not RecruitingNCT05972525
What this trial is testing

What Matters to Patients With Severe Hip or Knee Osteoarthritis?

Who this might be right for
Hip OsteoarthritisKnee Osteoarthritis
Vejle Hospital 615
Testing effectiveness (Phase 2)Study completedNCT05079035
What this trial is testing

Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA

Who this might be right for
Knee OsteoarthritisKnee Pain ChronicKnee Arthritis
BioTissue Holdings, Inc 90
Not applicableStudy completedNCT01998321
What this trial is testing

PSI for Bilateral Simultaneous TKA in Sever Varus

Who this might be right for
Knee Osteoarthritis
October 6 University 100
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