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Results for “Severe Liver Impairment”

67 trials

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Showing 20 of 67 results

Not applicableLooking for participantsNCT05399745
What this trial is testing

BILACO Trial: Biliary Atresia - a Severe Complex Congenital Liver Disease

Who this might be right for
Biliary AtresiaCognitive Impairment
Rigshospitalet, Denmark 100
Early research (Phase 1)Study completedNCT03376841
What this trial is testing

Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites

Who this might be right for
Hepatic Impairment
Allergan 16
Early research (Phase 1)Study completedNCT04587622
What this trial is testing

Pharmacokinetic Study of Icenticaftor in Participants With Hepatic Impairment

Who this might be right for
Hepatic Failure
Novartis Pharmaceuticals 40
Early research (Phase 1)Study completedNCT05116826
What this trial is testing

Nitazoxanide Pharmacokinetic Parameters in Hepatic Impaired Patients

Who this might be right for
Moderate Hepatic ImpairmentSevere Hepatic ImpairmentLiver Diseases
Genfit 25
Early research (Phase 1)Study completedNCT04552808
What this trial is testing

To Evaluate the Pharmacokinetics and Safety of Yimitasvir Phosphate Capsules in Subjects With Moderate and Severe Liver Function Impairment and in Healthy Subjects

Who this might be right for
Hepatic Impairment
Sunshine Lake Pharma Co., Ltd. 16
Early research (Phase 1)Study completedNCT02397707
What this trial is testing

Pharmacokinetics of Voxilaprevir in Adults With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Who this might be right for
HCV Infection
Gilead Sciences 33
Large-scale testing (Phase 3)Study completedNCT02487199
What this trial is testing

Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir in Adults With Genotype 1a or Genotype 4 Chronic Hepatitis C Virus (HCV) Infection, With Severe Kidney Impairment or End Stage Kidney Disease

Who this might be right for
Hepatitis C Virus (HCV)
AbbVie 18
Early research (Phase 1)Study completedNCT06535399
What this trial is testing

Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Celgene 29
Early research (Phase 1)Ended earlyNCT03295266
What this trial is testing

Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006)

Who this might be right for
Hepatic InsufficiencyAntibacterial Agents
Merck Sharp & Dohme LLC 9
Early research (Phase 1)Study completedNCT05882032
What this trial is testing

LY3502970 in Participants With Impaired and Normal Liver Function

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 29
Early research (Phase 1)Study completedNCT03890809
What this trial is testing

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Who this might be right for
Liver DysfunctionHealthy Volunteers
Bristol-Myers Squibb 32
Early research (Phase 1)Study completedNCT02002767
What this trial is testing

Study to Evaluate the Pharmacokinetics of Velpatasvir in Participants With Normal Renal Function and Severe Renal Impairment

Who this might be right for
Hepatitis C Virus
Gilead Sciences 19
Early research (Phase 1)Study completedNCT01580306
What this trial is testing

Pharmacokinetics and Safety of BI 201335 in Patients With Mild to Severe Renal Impairment

Who this might be right for
Hepatitis C
Boehringer Ingelheim 32
Early research (Phase 1)Study completedNCT06812780
What this trial is testing

Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD2389

Who this might be right for
Hepatic Impairment
AstraZeneca 35
Early research (Phase 1)Study completedNCT05835180
What this trial is testing

A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Who this might be right for
Non-alcoholic SteatohepatitisHepatic ImpairmentCirrhosis
Sagimet Biosciences Inc. 48
Early research (Phase 1)Study completedNCT05224609
What this trial is testing

Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Who this might be right for
Moderate Hepatic ImpairmentSevere Hepatic ImpairmentHealthy Volunteers
Pfizer 21
Early research (Phase 1)Study completedNCT00118170
What this trial is testing

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt Lymphoma+42 more
National Cancer Institute (NCI) 150
Early research (Phase 1)Looking for participantsNCT07023354
What this trial is testing

Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

Who this might be right for
HealthyHepatic Impairment
Boehringer Ingelheim 32
Early research (Phase 1)Looking for participantsNCT07401862
What this trial is testing

Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

Who this might be right for
Hepatic Insufficiency
Eli Lilly and Company 36
Not applicableStudy completedNCT02813538
What this trial is testing

Major Liver Resection: Early Clotting Disorders and Functional Impairment.

Who this might be right for
Hepatic InsufficiencyBlood Coagulation Disorders
Hospital General Universitario Gregorio Marañon 60
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