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Results for “Severe Pain in Knee Osteoarthritis”

101 trials

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Showing 20 of 101 results

Large-scale testing (Phase 3)Study completedNCT00421928
What this trial is testing

Tapentadol (CG5503)

Who this might be right for
Osteoarthritis, KneePain
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 1,030
Large-scale testing (Phase 3)Study completedNCT05603754
What this trial is testing

A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES)

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 496
Testing effectiveness (Phase 2)Study completedNCT04129944
What this trial is testing

Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, Knee
Unity Biotechnology, Inc. 183
Not applicableStudy completedNCT00435292
What this trial is testing

Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
Primus Pharmaceuticals 350
Post-approval studies (Phase 4)WithdrawnNCT02032927
What this trial is testing

Treatment of Chronic Pain From Osteoarthritis

Who this might be right for
Chronic Pain
Fondazione IRCCS Policlinico San Matteo di Pavia
Not applicableStudy completedNCT00928837
What this trial is testing

Study of Flavocoxid (Limbrel) Versus Naproxen in Subjects With Moderate-Severe Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
Primus Pharmaceuticals 350
Large-scale testing (Phase 3)Study completedNCT01511939
What this trial is testing

Trial to See if Topical Pennsaid for Knee Pain Affects Coagulation Values in Patients Who Are Also Taking Anticoagulants

Who this might be right for
Osteoarthritis of the KneeCoagulopathy
Nathan Wei, MD, FACP, FACR: 22
Large-scale testing (Phase 3)Ended earlyNCT00982280
What this trial is testing

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.

Who this might be right for
Chronic PainOsteoarthritis
Grünenthal GmbH 82
Testing effectiveness (Phase 2)Ended earlyNCT00973141
What this trial is testing

A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain

Who this might be right for
OsteoarthritisOsteoarthritis, HipOsteoarthritis, Knee+3 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 467
Not applicableStudy completedNCT05319964
What this trial is testing

Anti-gravity Treadmill Training in Patients With Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01619839
What this trial is testing

Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain

Who this might be right for
Osteoarthritis of the Knee
Nektar Therapeutics 296
Testing effectiveness (Phase 2)UnknownNCT04885972
What this trial is testing

Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis

Who this might be right for
Osteoarthritis, KneeKnee OsteoarthritisKnee Pain Chronic
Sorrento Therapeutics, Inc. 124
Testing effectiveness (Phase 2)Ended earlyNCT01094262
What this trial is testing

A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis

Who this might be right for
OsteoarthritisOsteoarthritis, KneePain+2 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 196
Not applicableEnded earlyNCT04349956
What this trial is testing

Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo

Who this might be right for
Knee Osteoarthritis
Unity Biotechnology, Inc. 161
Testing effectiveness (Phase 2)Study completedNCT02253966
What this trial is testing

Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty

Who this might be right for
Knee Joint OsteoarthrosisHyperalgesiaSevere Movement Related Pain
Rigshospitalet, Denmark 48
Not applicableStudy completedNCT05274932
What this trial is testing

Exercise With Blood Flow Restriction in Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Valencia 22
Not applicableStudy completedNCT03719417
What this trial is testing

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Who this might be right for
Knee OsteoarthritisPost-traumatic Osteoarthritis
University of Missouri-Columbia 14
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04750252
What this trial is testing

Safety and Tolerability of StroMel™ in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint

Who this might be right for
Osteo Arthritis Knee
Akan Biosciences, LLC 20
Large-scale testing (Phase 3)Study completedNCT01559701
What this trial is testing

Long-term Safety of PF-00345439 (Oxycodone)

Who this might be right for
Pain
Pain Therapeutics 823
Testing effectiveness (Phase 2)Study completedNCT01768975
What this trial is testing

Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee

Who this might be right for
Osteoarthritis of the Knee
Olatec Therapeutics LLC 79
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