Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe Systemic Sclerosis”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Very early researchLooking for participantsNCT07000682
What this trial is testing

The Clinical Study on the Treatment of SSc With UTAA91 Injection.

Who this might be right for
Systemic Sclerosis (SSc)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 24
Testing effectiveness (Phase 2)WithdrawnNCT01047072
What this trial is testing

Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe Systemic Sclerosis

Who this might be right for
Systemic Scleroderma
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Not applicableLooking for participantsNCT04334031
What this trial is testing

Deployment o the Multidisciplinary Prospective Cohort Imminent

Who this might be right for
Chronic Inflammatory DiseaseAngioedemaSevere Asthma+6 more
University Hospital, Lille 2,200
Not applicableStudy completedNCT07469865
What this trial is testing

Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)

Who this might be right for
Dry Eye Disease
University Hospital, Ghent 46
Large-scale testing (Phase 3)Study completedNCT00114530
What this trial is testing

Scleroderma: Cyclophosphamide or Transplantation

Who this might be right for
Scleroderma, SystemicSclerosisAutoimmune Disease
National Institute of Allergy and Infectious Diseases (NIAID) 75
Early research (Phase 1)Active Not RecruitingNCT05869955
What this trial is testing

CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathySystemic Sclerosis+1 more
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 270
Not applicableNot Yet RecruitingNCT07593911
What this trial is testing

Evaluate MTM-H-001 Injection in Adult Patients With B-Cell-Related Autoimmune Diseases

Who this might be right for
Systemic Lupus Erthematosus (SLE)Lupus Nephritis (LN)Multiple Sclerosis+3 more
Beijing GoBroad Hospital 75
Testing effectiveness (Phase 2)Study completedNCT00379431
What this trial is testing

A Protocol Based Treatment for Early and Severe Systemic Sclerosis With (Anti-CD20), Rituximab

Who this might be right for
Early and Severe Systemic Sclerosis
University Hospital, Ghent 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT06655896
What this trial is testing

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, Diffuse
Novartis Pharmaceuticals 96
Early research (Phase 1)Looking for participantsNCT07115745
What this trial is testing

Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

Who this might be right for
Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 125
Large-scale testing (Phase 3)Study completedNCT03957681
What this trial is testing

KHK4827 in Patients With Systemic Sclerosis

Who this might be right for
Moderate to Severe Systemic Sclerosis
Kyowa Kirin Co., Ltd. 100
Not applicableStudy completedNCT03941184
What this trial is testing

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Who this might be right for
SCADAddison DiseaseAnkylosing Spondylitis+26 more
Mayo Clinic 114
Early research (Phase 1)Looking for participantsNCT07085676
What this trial is testing

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Who this might be right for
Systemic Sclerosis (SSc)Idiopathic Inflammatory Myopathy (IIM)Rheumatoid Arthritis (RA)+6 more
Polina Stepensky 120
Large-scale testing (Phase 3)Study completedNCT02050360
What this trial is testing

"As Required" Oral Sildenafil in Raynaud's Phenomenon

Who this might be right for
Raynaud's Phenomenon
University Hospital, Grenoble 41
Early research (Phase 1)Not Yet RecruitingNCT06978738
What this trial is testing

UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusAutoimmune Hemolytic AnemiaMyasthenia Gravis+4 more
Changzhou No.2 People's Hospital 18
Not applicableUnknownNCT05960058
What this trial is testing

Acceptance and Effectiveness of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Vaccination in Systemic Sclerosis Patients Treated by Autologous Hematopoietic Stem Cell Transplantation

Who this might be right for
Systemic SclerosisSARS-CoV 2 Vaccination
Assistance Publique - Hôpitaux de Paris 72
Large-scale testing (Phase 3)Study completedNCT00025818
What this trial is testing

Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome

Who this might be right for
Keratoconjunctivitis SiccaSjogren's SyndromeLupus Erythematosus, Systemic+2 more
Allergan 290
Very early researchNot Yet RecruitingNCT06982534
What this trial is testing

Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection.

Who this might be right for
Systemic Sclerosis (SSc)
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 24
Post-approval studies (Phase 4)WithdrawnNCT01497743
What this trial is testing

Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis

Who this might be right for
Scleroderma
University of Michigan
Not applicableUnknownNCT05947682
What this trial is testing

Manufacturing of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells for Treatment of Severe Systemic Sclerosis

Who this might be right for
Mesenchymal Stromal CellSystemic Sclerosis
Assistance Publique - Hôpitaux de Paris 6
Next Page