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Results for “Severe Ulcerative Colitis”

376 trials

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Showing 20 of 376 results

Testing effectiveness (Phase 2)Looking for participantsNCT06979336
What this trial is testing

Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Genentech, Inc. 224
Large-scale testing (Phase 3)Study completedNCT03524092
What this trial is testing

A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Eli Lilly and Company 1,328
Testing effectiveness (Phase 2)Study completedNCT05291689
What this trial is testing

A Phase 2a Open-Label Study to Evaluate the Efficacy and Safety of MORF-057 in Adults With UC

Who this might be right for
Inflammatory Bowel DiseasesColitis, Ulcerative
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) 39
Testing effectiveness (Phase 2)Study completedNCT04877990
What this trial is testing

Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis

Who this might be right for
Crohn DiseaseUlcerative Colitis
Bristol-Myers Squibb 67
Early research (Phase 1)Study completedNCT05084261
What this trial is testing

An Investigation of Oral BT051 in Subjects With Moderately to Severely Active Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Adiso Therapeutics 24
Testing effectiveness (Phase 2)Study completedNCT05372939
What this trial is testing

Study of the Efficacy and Safety of AMT-101 in Combination With Adalimumab in Subjects With Ulcerative Colitis (MARKET)

Who this might be right for
Ulcerative Colitis
Applied Molecular Transport 51
Testing effectiveness (Phase 2)Looking for participantsNCT07012395
What this trial is testing

Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative ColitisInflammatory Bowel DiseasesColitis+1 more
Spyre Therapeutics, Inc. 645
Large-scale testing (Phase 3)Study completedNCT01458951
What this trial is testing

Evaluate Both The Efficacy and Safety Profile of CP-690,550 In Patients With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 547
Testing effectiveness (Phase 2)Looking for participantsNCT06420492
What this trial is testing

Study of Novel Therapeutics for Acute Remedy of Colitis

Who this might be right for
Ulcerative ColitisUlcerative Colitis Chronic ModerateUlcerative Colitis Chronic Severe
Brigham and Women's Hospital 20
Large-scale testing (Phase 3)Active Not RecruitingNCT03221036
What this trial is testing

Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis

Who this might be right for
Moderately to Severely Active Ulcerative Colitis
Takeda 392
Large-scale testing (Phase 3)Looking for participantsNCT05076175
What this trial is testing

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Bristol-Myers Squibb 120
Not applicableStudy completedNCT02229344
What this trial is testing

Study of Clinical Course of Newly Diagnosed Moderate to Severe Ulcerative Colitis in Korea

Who this might be right for
Colitis, Ulcerative
Janssen Korea, Ltd., Korea 368
Testing effectiveness (Phase 2)Study completedNCT05570006
What this trial is testing

Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
AbbVie 30
Early research (Phase 1)Looking for participantsNCT07665723
What this trial is testing

An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis

Who this might be right for
Active Ulcerative Colitis
Hoffmann-La Roche 25
Large-scale testing (Phase 3)Looking for participantsNCT06660693
What this trial is testing

Comparison of Medical RESCUE Strategies for Patients With Steroid-refractory Acute Severe Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
McMaster University 134
Testing effectiveness (Phase 2)WithdrawnNCT01846026
What this trial is testing

Ulcerative Colitis and Vitamin D Supplementation

Who this might be right for
Ulcerative Colitis
University Hospital of North Norway
Testing effectiveness (Phase 2)Study completedNCT02840721
What this trial is testing

Safety, Efficacy, and Tolerability Study of PF-06480605 in Subjects With Moderate to Severe Ulcerative Colitis.

Who this might be right for
Colitis, Ulcerative
Telavant, Inc. 50
Testing effectiveness (Phase 2)Looking for participantsNCT07374471
What this trial is testing

MB-001 in Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
Mage Biologics 100
Early research (Phase 1)Study completedNCT06281704
What this trial is testing

AK101 in Subjects With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Akeso 34
Post-approval studies (Phase 4)Looking for participantsNCT05867329
What this trial is testing

Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis Acute
Berinstein, Jeffrey 700
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