Large-scale testing (Phase 3)Ended earlyNCT00102791What this trial is testingA Stratified Sickle Event Randomized Trial (ASSERT)Who this might be right forSickle Cell Disease Icagen 297
Testing effectiveness (Phase 2)Ended earlyNCT04028700What this trial is testingThe Impact of Oxidative Stress on Erythrocyte BiologyWho this might be right forSickle Cell Disease Without Crisis University of North Carolina, Chapel Hill 8
Post-approval studies (Phase 4)Study completedNCT04662931What this trial is testingAn Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 140
Large-scale testing (Phase 3)Active Not RecruitingNCT03814746What this trial is testingStudy of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 254
Not applicableStudy completedNCT06886477What this trial is testingSickle Cell, Pain and Mediterranean DietWho this might be right forSickle CellSickle Cell DiseaseSickle Cell Disease Without Crisis+1 more University of Illinois at Chicago 37
Testing effectiveness (Phase 2)Study completedNCT03264989What this trial is testingPharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC)Who this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 57
Early research (Phase 1)Study completedNCT02989701What this trial is testingPilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Without Crisis Alessandra Biffi 6
Testing effectiveness (Phase 2)Study completedNCT01895361What this trial is testingStudy to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain CrisesWho this might be right forSickle Cell Disease Reprixys Pharmaceutical Corporation 198
Testing effectiveness (Phase 2)Study completedNCT03474965What this trial is testingStudy of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 117
Large-scale testing (Phase 3)Looking for participantsNCT06439082What this trial is testingInvestigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)Who this might be right forSickle Cell Disease Novartis Pharmaceuticals 354