Early research (Phase 1)Active Not RecruitingNCT03282656What this trial is testingGene Transfer for Sickle Cell DiseaseWho this might be right forSickle Cell Disease David Williams 10
Testing effectiveness (Phase 2)Ended earlyNCT00586209What this trial is testingL-Glutamine Therapy for Sickle Cell AnemiaWho this might be right forSickle Cell AnemiaThalassemia Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 15
Not applicableStudy completedNCT00512226What this trial is testingIron Overload Assesment in Sickle Cell Anemia and Sickle Cell ThalassemiaWho this might be right forSickle Cell AnemiaSickle Cell ThalassemiaIron Overload+1 more HaEmek Medical Center, Israel 50
Not applicableLooking for participantsNCT04416178What this trial is testingSickle Cell Disease and the Genomic and Gene Therapy Needs of StakeholdersWho this might be right forSickle Cell Disease St. Jude Children's Research Hospital 352
Not applicableNot Yet RecruitingNCT05883254What this trial is testingPumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia IntermediaWho this might be right forSickle Cell Disease, Beta Thalassemia Intermedia Assiut University 80
Not applicableLooking for participantsNCT05414045What this trial is testingAutologous Testicular Tissue TransplantationWho this might be right forCancerSickle Cell ThalassemiaHematologic Diseases Universitair Ziekenhuis Brussel 5
Not applicableStudy completedNCT00971698What this trial is testingThe Spleen in Sickle Cell Anemia and Sickle Cell ThalassemiaWho this might be right forSickle Cell AnemiaThalassemia HaEmek Medical Center, Israel 50
Large-scale testing (Phase 3)Looking for participantsNCT05477563What this trial is testingEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell DiseaseWho this might be right forBeta-ThalassemiaThalassemiaHematologic Diseases+4 more Vertex Pharmaceuticals Incorporated 26
Not applicableStudy completedNCT00427661What this trial is testingA Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative RegimenWho this might be right forSickle Cell DiseaseThalassemiaHemoglobinopathies University of Pittsburgh 8
Not applicableActive Not RecruitingNCT03376893What this trial is testingEpidemiology of Silent and Overt Strokes in Sickle Cell DiseaseWho this might be right forAnemia, Sickle CellSickle Cell DiseaseStroke+2 more Vanderbilt University Medical Center 102
Early research (Phase 1)Study completedNCT01522547What this trial is testingStudy to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell DiseaseWho this might be right forAnemia, Sickle Cell Celgene 12
Not applicableTemporarily Not AvailableNCT07640815What this trial is testingExpanded Access Protocol for Gene Therapy Utilizing shmiR Lentivirus Vector to Induce Fetal Hemoglobin in Sickle Cell DiseaseWho this might be right forSickle Cell Disease David Williams
Not applicableNot Yet RecruitingNCT07774351What this trial is testingA Clinical Exploratory Study of YOLT-204 in the Treatment of HemoglobinopathiesWho this might be right forHemoglobinopathies Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 30
Testing effectiveness (Phase 2)Enrolling By InvitationNCT04432623What this trial is testingThe BENeFiTS Trial in Beta Thalassemia IntermediaWho this might be right forBeta Thalassemia IntermediaSickle Cell Disease Phoenicia BioScience 36
Testing effectiveness (Phase 2)Study completedNCT00029380What this trial is testingCord Blood Transplantation for Sickle Cell Anemia and ThalassemiaWho this might be right forHematologic DiseasesAnemia, Sickle CellBeta-Thalassemia+1 more National Heart, Lung, and Blood Institute (NHLBI) 30
Testing effectiveness (Phase 2)Ended earlyNCT03333486What this trial is testingFludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerWho this might be right forAccelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more Roswell Park Cancer Institute 31
Not applicableStudy completedNCT00735488What this trial is testingSickle Cell Anemia Screening and Prevention in Northern IsraelWho this might be right forThalassemiaSickle Cell Anemia HaEmek Medical Center, Israel 69
Testing effectiveness (Phase 2)Active Not RecruitingNCT00061568What this trial is testingImproving the Results of Bone Marrow Transplantation for Patients With Severe Congenital AnemiasWho this might be right forCongenital Hemolytic AnemiaSickle Cell Disease National Heart, Lung, and Blood Institute (NHLBI) 130
Not applicableEnded earlyNCT02179359What this trial is testingHematopoietic Stem Cell Transplant for High Risk HemoglobinopathiesWho this might be right forSickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more Masonic Cancer Center, University of Minnesota 38
Early research (Phase 1)Study completedNCT06813924What this trial is testingA Research Study of the Effect of Etavopivat on Other Drugs in Healthy ParticipantsWho this might be right forHealthy Volunteers Sickle Cell Disease, Thalassemia Novo Nordisk A/S 37