Testing effectiveness (Phase 2)WithdrawnNCT04474626What this trial is testingIsoquercetin in Sickle Cell AnemiaWho this might be right forSickle Cell DiseaseSickle Cell-Beta0-Thalassemia Jeffrey Zwicker, MD
Not applicableStudy completedNCT04579926What this trial is testingPINPOINT: Gaming Technology for SCD PainWho this might be right forSickle Cell DiseaseSickle Cell Anemia in ChildrenSickle Cell Thalassemia+1 more Klein Buendel, Inc. 24
Testing effectiveness (Phase 2)Looking for participantsNCT07599176What this trial is testingPartial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsWho this might be right forSickle Cell DiseaseBeta-thalassemia National Heart, Lung, and Blood Institute (NHLBI) 90
Testing effectiveness (Phase 2)Ended earlyNCT00040417What this trial is testingBone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk HemoglobinopathiesWho this might be right forSickle Cell AnemiaHemoglobinopathyThalassemia Baylor College of Medicine 15
Not applicableStudy completedNCT04029142What this trial is testingScreening for Hemoglobinopathies in Pregnant WomenWho this might be right forHemoglobinopathies University Hospital, Basel, Switzerland 1,785
Testing effectiveness (Phase 2)Ended earlyNCT06078696What this trial is testingSiplizumab for Sickle Cell Disease TransplantWho this might be right forAnemia, Sickle Cell Columbia University 1
Large-scale testing (Phase 3)Study completedNCT01179217What this trial is testingA Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemiaWho this might be right forSickle Cell AnemiaSickle ß0-Thalassemia Emmaus Medical, Inc. 230
Not applicableStudy completedNCT03609840What this trial is testingStudy of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant PatientsWho this might be right forHematologic MalignanciesNonmalignant DiseasesImmune Deficiency+5 more University of California, San Francisco 25
Not applicableStudy completedNCT01319552What this trial is testingFresh Versus Old Red Blood Cells for TransfusionWho this might be right forIron, Abnormal Blood LevelOther Abnormal Blood Chemistry Columbia University 14
Not applicableAvailableNCT01881334What this trial is testingExpanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood TransplantsWho this might be right forHematologic MalignanciesInborn Errors of Metabolism DisordersImmune Deficiencies Joanne Kurtzberg, MD
Testing effectiveness (Phase 2)Ended earlyNCT00586209What this trial is testingL-Glutamine Therapy for Sickle Cell AnemiaWho this might be right forSickle Cell AnemiaThalassemia Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT05353647What this trial is testingA Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)Who this might be right forSickle Cell Disease David Williams 25
Not applicableStudy completedNCT04523376What this trial is testingPilot Study PBSCT With TCRab Depletion For HemoglobinopathiesWho this might be right forSickle Cell DiseaseThalassemia Major Timothy Olson 8
Early research (Phase 1)Study completedNCT02712346What this trial is testingThe Role of Endothelin-1 in Sickle Cell DiseaseWho this might be right forSickle Cell Anemia Augusta University 26
Not applicableStudy completedNCT03609814What this trial is testingStudy of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)Who this might be right forHematologic MalignanciesNonmalignant DiseasesImmunodeficiencies+5 more University of California, San Francisco 30
Not applicableStudy completedNCT00480974What this trial is testingLong Term Follow up in Sickle Cell Patients Treated by HydroxyureaWho this might be right forSickle Cell AnemiaSickle Cell Thalassemia HaEmek Medical Center, Israel 20
Early research (Phase 1)Study completedNCT03492931What this trial is testingPK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4)Who this might be right forSickle Cell Disease AstraZeneca 21
Large-scale testing (Phase 3)Looking for participantsNCT05477563What this trial is testingEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell DiseaseWho this might be right forBeta-ThalassemiaThalassemiaHematologic Diseases+4 more Vertex Pharmaceuticals Incorporated 26
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07401823What this trial is testingOpen-Label Extension Study to Pioneer Study 6058-SCD-101Who this might be right forSickle Cell Disease Fulcrum Therapeutics 50
Not applicableEnded earlyNCT02179359What this trial is testingHematopoietic Stem Cell Transplant for High Risk HemoglobinopathiesWho this might be right forSickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more Masonic Cancer Center, University of Minnesota 38