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Results for “Sinonasal Malignancies”

37 trials

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Showing 20 of 37 results

Not applicableLooking for participantsNCT05898074
What this trial is testing

Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery

Who this might be right for
Skull Base NeoplasmsCerebrospinal Fluid LeakageNasal; Hypertrophy, Mucous Membrane (Septum)
Indiana University 30
Early research (Phase 1)Looking for participantsNCT06868433
What this trial is testing

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT06176989
What this trial is testing

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Who this might be right for
Metastatic ChondrosarcomaLocally Advanced ChondrosarcomaMetastatic Sinonasal Adenocarcinoma+7 more
National Cancer Institute (NCI) 40
Not applicableNo Longer AvailableNCT03874455
What this trial is testing

Tazemetostat Expanded Access Program for Adults With Solid Tumors

Who this might be right for
Epithelioid Sarcoma (Ex-US Only)Spindle Cell SarcomaSinonasal Carcinoma+17 more
Epizyme, Inc.
Large-scale testing (Phase 3)Active Not RecruitingNCT05063552
What this trial is testing

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
National Cancer Institute (NCI)
Post-approval studies (Phase 4)Looking for participantsNCT03014687
What this trial is testing

Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions

Who this might be right for
AntibioticsPituitary Adenoma
St. Joseph's Hospital and Medical Center, Phoenix 116
Testing effectiveness (Phase 2)Looking for participantsNCT06814496
What this trial is testing

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Who this might be right for
MelanomaMedullary Thyroid CancerSinonasal Undifferentiated Carcinoma+8 more
University of Arizona 30
Early research (Phase 1)Active Not RecruitingNCT02567422
What this trial is testing

Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer

Who this might be right for
Head and Neck Carcinoma of Unknown PrimaryHead and Neck Squamous Cell CarcinomaStage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7+9 more
National Cancer Institute (NCI) 43
Not applicableWithdrawnNCT02580136
What this trial is testing

Esthesioneuroblastoma: Outcomes After Treatment

Who this might be right for
Esthesioneuroblastoma, Olfactory
Ricardo L. Carrau, MD
Not applicableStudy completedNCT04788264
What this trial is testing

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

Who this might be right for
Head and Neck CarcinomaHypopharyngeal CarcinomaLaryngeal Carcinoma+13 more
Thomas Jefferson University 12
Not applicableActive Not RecruitingNCT06617910
What this trial is testing

Stereotactic Radiotherapy for Sinonasal Malignancy

Who this might be right for
Head and Neck Neoplasms
Taichung Veterans General Hospital 16
Early research (Phase 1)Not Yet RecruitingNCT07156227
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell CarcinomaRecurrent Hypopharyngeal Squamous Cell Carcinoma+27 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT01827423
What this trial is testing

Squamous Cell Carcinoma Antigen Analysis at the University Hospital Ostrava

Who this might be right for
Nasal PolypsNasal DiseasesPapilloma
University Hospital Ostrava 20
Testing effectiveness (Phase 2)Study completedNCT03274414
What this trial is testing

A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages

Who this might be right for
Paranasal Sinus CancerNasal Cavity TumorNasal Cavity Adenocarcinoma
Memorial Sloan Kettering Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT00707473
What this trial is testing

Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer

Who this might be right for
Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell CarcinomaNasal Cavity and Paranasal Sinus Poorly Differentiated CarcinomaSinonasal Undifferentiated Carcinoma+4 more
M.D. Anderson Cancer Center
Not applicableLooking for participantsNCT06662058
What this trial is testing

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Cutaneous Squamous Cell Carcinoma of the Head and NeckHead and Neck Carcinoma of Unknown Primary+30 more
Emory University 118
Testing effectiveness (Phase 2)Study completedNCT03082534
What this trial is testing

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

Who this might be right for
HNSCCLip SCCOral Cavity Cancer+9 more
University of California, San Diego 78
Large-scale testing (Phase 3)Active Not RecruitingNCT00588770
What this trial is testing

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Neck Squamous Cell Carcinoma of Unknown PrimaryRecurrent Hypopharyngeal Squamous Cell CarcinomaRecurrent Laryngeal Squamous Cell Carcinoma+32 more
National Cancer Institute (NCI) 403
Testing effectiveness (Phase 2)Looking for participantsNCT04879654
What this trial is testing

Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery

Who this might be right for
Malignant MelanomaSinonasal Melanoma
Eye & ENT Hospital of Fudan University 45
Early research (Phase 1)UnknownNCT03925285
What this trial is testing

Image Guided Surgery in Sinonasal Inverted Papilloma

Who this might be right for
Inverted PapillomaMolecular Fluorescence Imaging
University Medical Center Groningen 6
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