Not applicableActive Not RecruitingNCT06617910What this trial is testingStereotactic Radiotherapy for Sinonasal MalignancyWho this might be right forHead and Neck Neoplasms Taichung Veterans General Hospital 16
Not applicableUnknownNCT01586767What this trial is testingIntensity-Modulated or Proton Radiation Therapy for Sinonasal MalignancyWho this might be right forAdenoid Cystic CarcinomaSquamous Cell CarcinomaSinonasal Carcinoma+6 more Massachusetts General Hospital 45
Not applicableUnknownNCT03942380What this trial is testingCell-free Tumor DNA in Head and Neck Cancer PatientsWho this might be right forHead and Neck CancerHead and Neck NeoplasmsHead and Neck Squamous Cell Carcinoma+24 more Christian von Buchwald 500
Early research (Phase 1)Looking for participantsNCT06868433What this trial is testingTMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell CancerWho this might be right forClinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more Emory University
Not applicableNo Longer AvailableNCT03874455What this trial is testingTazemetostat Expanded Access Program for Adults With Solid TumorsWho this might be right forEpithelioid Sarcoma (Ex-US Only)Spindle Cell SarcomaSinonasal Carcinoma+17 more Epizyme, Inc.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07616141What this trial is testingNeoadjuvant Anlotinib and Epirubicin for T4 Sinonasal Adenoid Cystic CarcinomaWho this might be right forAdenoid Cystic Carcinoma Eye & ENT Hospital of Fudan University 76
Not applicableLooking for participantsNCT05898074What this trial is testingRole of Novel RADA16 Hydrogel in Endoscopic Skull Base SurgeryWho this might be right forSkull Base NeoplasmsCerebrospinal Fluid LeakageNasal; Hypertrophy, Mucous Membrane (Septum) Indiana University 30
Early research (Phase 1)Active Not RecruitingNCT02567422What this trial is testingTesting the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck CancerWho this might be right forHead and Neck Carcinoma of Unknown PrimaryHead and Neck Squamous Cell CarcinomaStage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7+9 more National Cancer Institute (NCI) 43
Testing effectiveness (Phase 2)Study completedNCT01220752What this trial is testingTreatment of Malignant Sinonasal Tumours With Intensity-modulated Radiotherapy (IMRT) and Carbon Ion Boost (C12)Who this might be right forSinonasal MalignanciesAdenocarcinoma and Squamous Cell Carcinoma of the Paranasal Sinuses Heidelberg University 36
Large-scale testing (Phase 3)Active Not RecruitingNCT05063552What this trial is testingTesting the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck CancersWho this might be right forClinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT04879654What this trial is testingToripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic SurgeryWho this might be right forMalignant MelanomaSinonasal Melanoma Eye & ENT Hospital of Fudan University 45
Testing effectiveness (Phase 2)Looking for participantsNCT07281417What this trial is testingTesting the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell CarcinomaWho this might be right forSinonasal Squamous Cell CarcinomaStage III Sinonasal Cancer AJCC v8Stage IVA Sinonasal Cancer AJCC v8+1 more National Cancer Institute (NCI) 108
Testing effectiveness (Phase 2)Looking for participantsNCT07320508What this trial is testingEpirubicin Interventional Chemotherapy for Sinonasal Adenoid Cystic Carcinoma (SNACC): A Prospective StudyWho this might be right forAdenoid Cystic CarcinomaSinonasal CarcinomaEpirubicin Eye & ENT Hospital of Fudan University 100
Large-scale testing (Phase 3)Active Not RecruitingNCT00588770What this trial is testingChemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaWho this might be right forNeck Squamous Cell Carcinoma of Unknown PrimaryRecurrent Hypopharyngeal Squamous Cell CarcinomaRecurrent Laryngeal Squamous Cell Carcinoma+32 more National Cancer Institute (NCI) 403
Testing effectiveness (Phase 2)WithdrawnNCT05879484What this trial is testingStudy of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERASWho this might be right forSinonasal CancerSquamous Non-small Cell Lung CancerLung Cancer+3 more National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT05172245What this trial is testingTesting the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck CancerWho this might be right forClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Carcinoma of Unknown PrimaryLocally Advanced Head and Neck Squamous Cell Carcinoma+23 more National Cancer Institute (NCI) 46
Not applicableWithdrawnNCT02580136What this trial is testingEsthesioneuroblastoma: Outcomes After TreatmentWho this might be right forEsthesioneuroblastoma, Olfactory Ricardo L. Carrau, MD
Testing effectiveness (Phase 2)Looking for participantsNCT06176989What this trial is testingEnasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base TumorsWho this might be right forMetastatic ChondrosarcomaLocally Advanced ChondrosarcomaMetastatic Sinonasal Adenocarcinoma+7 more National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Study completedNCT03082534What this trial is testingPembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell CarcinomaWho this might be right forHNSCCLip SCCOral Cavity Cancer+9 more University of California, San Diego 78
Post-approval studies (Phase 4)Looking for participantsNCT03014687What this trial is testingProphylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary LesionsWho this might be right forAntibioticsPituitary Adenoma St. Joseph's Hospital and Medical Center, Phoenix 116