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Results for “Sodium Zirconium Cyclosilicate”

34 trials

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Showing 20 of 34 results

Large-scale testing (Phase 3)Study completedNCT05382988
What this trial is testing

Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy

Who this might be right for
Sodium Zirconium CyclosilicateHyperkalemiaHyperparathyroidism, Secondary
Guangdong Provincial People's Hospital 62
Large-scale testing (Phase 3)Study completedNCT03172702
What this trial is testing

Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia

Who this might be right for
Hyperkalemia
AstraZeneca 150
Large-scale testing (Phase 3)Looking for participantsNCT03813407
What this trial is testing

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Who this might be right for
Hyperkalaemia
AstraZeneca 140
Large-scale testing (Phase 3)Ended earlyNCT05056727
What this trial is testing

Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia

Who this might be right for
Renal Insufficiency, ChronicHyperkalemia
AstraZeneca 1,112
Early research (Phase 1)Study completedNCT04788641
What this trial is testing

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Who this might be right for
Hyperkalaemia
AstraZeneca 62
Post-approval studies (Phase 4)Study completedNCT04676646
What this trial is testing

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

Who this might be right for
HyperkalaemiaHeart Failure With Reduced Ejection Fraction
AstraZeneca 366
Not applicableStudy completedNCT06635499
What this trial is testing

VITALIZE.Use and Effectiveness of Sodium Zirconium Cyclosilicate (LokelmaTM) in the Real-world Setting in Spain

Who this might be right for
Hyperkalaemia
AstraZeneca 232
Early research (Phase 1)UnknownNCT04727840
What this trial is testing

Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial)

Who this might be right for
Chronic Kidney DiseasesHyperkalemia
Brigham and Women's Hospital 20
Large-scale testing (Phase 3)Study completedNCT03303521
What this trial is testing

Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients.

Who this might be right for
Hyperkalemia
AstraZeneca 196
Post-approval studies (Phase 4)Ended earlyNCT04997161
What this trial is testing

Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia

Who this might be right for
Hyperkalaemia
AstraZeneca 3
Testing effectiveness (Phase 2)Looking for participantsNCT07029503
What this trial is testing

Swedish Cardiac And Renal Failure Study-1

Who this might be right for
HFrEF - Heart Failure With Reduced Ejection FractionChronic Kidney Disease
Karolinska Institutet 40
Early research (Phase 1)Study completedNCT03283267
What this trial is testing

A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)

Who this might be right for
Hyperkalemia
AstraZeneca 22
Post-approval studies (Phase 4)UnknownNCT04063930
What this trial is testing

The Effect of Sodium Zirconium Cyclosilicate on Albuminuria in Patients With Type 2 Diabetes and Hyperkalemia

Who this might be right for
Type 2 Diabetes Mellitus With Kidney Complications
Steno Diabetes Center Copenhagen 20
Post-approval studies (Phase 4)Study completedNCT05535920
What this trial is testing

A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia

Who this might be right for
Hyperkalemia
NephroNet, Inc. 88
Large-scale testing (Phase 3)Study completedNCT02163499
What this trial is testing

Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months

Who this might be right for
Hyperkalemia
ZS Pharma, Inc. 751
Large-scale testing (Phase 3)Looking for participantsNCT06578533
What this trial is testing

Keeping RAASi Treatment With Optimal Potassium Control

Who this might be right for
Chronic Kidney Diseases
Fundación para la Investigación del Hospital Clínico de Valencia 78
Large-scale testing (Phase 3)Study completedNCT04217590
What this trial is testing

Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects

Who this might be right for
Hyperkalemia
AstraZeneca 134
Not applicableStudy completedNCT04207203
What this trial is testing

Healthy Diet Rich in Potassium to Chronic Kidney Disease With Sodium Zirconium Cyclosilicate: A Feasibility Study

Who this might be right for
Chronic Kidney Disease stage4Chronic Kidney Disease Stage 5Hyperkalemia
Karolinska Institutet 26
Large-scale testing (Phase 3)Ended earlyNCT04727528
What this trial is testing

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease

Who this might be right for
HyperkalaemiaMetabolic AcidosisChronic Kidney Disease
AstraZeneca 39
Large-scale testing (Phase 3)Ended earlyNCT04847232
What this trial is testing

Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

Who this might be right for
Hyperkalemia
AstraZeneca 2,690
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