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Results for “Sodium Zirconium Cyclosilicate”

34 trials

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Showing 20 of 34 results

Large-scale testing (Phase 3)Looking for participantsNCT06578533
What this trial is testing

Keeping RAASi Treatment With Optimal Potassium Control

Who this might be right for
Chronic Kidney Diseases
Fundación para la Investigación del Hospital Clínico de Valencia 78
Large-scale testing (Phase 3)Looking for participantsNCT03813407
What this trial is testing

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Who this might be right for
Hyperkalaemia
AstraZeneca 140
Large-scale testing (Phase 3)Study completedNCT03528681
What this trial is testing

Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia.

Who this might be right for
Hyperkalemia
AstraZeneca 270
Not applicableStudy completedNCT06185660
What this trial is testing

A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece

Who this might be right for
Hyperkalaemia
AstraZeneca 125
Large-scale testing (Phase 3)Study completedNCT03172702
What this trial is testing

Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia

Who this might be right for
Hyperkalemia
AstraZeneca 150
Large-scale testing (Phase 3)Ended earlyNCT04847232
What this trial is testing

Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

Who this might be right for
Hyperkalemia
AstraZeneca 2,690
Large-scale testing (Phase 3)UnknownNCT05004363
What this trial is testing

Lokelma for RAAS Maximisation in CKD & Heart Failure.

Who this might be right for
Chronic Kidney DiseasesHeart Failure With Reduced Ejection FractionHyperkalemia+2 more
St George's, University of London 130
Large-scale testing (Phase 3)Ended earlyNCT05056727
What this trial is testing

Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia

Who this might be right for
Renal Insufficiency, ChronicHyperkalemia
AstraZeneca 1,112
Post-approval studies (Phase 4)UnknownNCT04063930
What this trial is testing

The Effect of Sodium Zirconium Cyclosilicate on Albuminuria in Patients With Type 2 Diabetes and Hyperkalemia

Who this might be right for
Type 2 Diabetes Mellitus With Kidney Complications
Steno Diabetes Center Copenhagen 20
Testing effectiveness (Phase 2)Ended earlyNCT03532009
What this trial is testing

Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure

Who this might be right for
Heart Failure
AstraZeneca 182
Not applicableStudy completedNCT06635499
What this trial is testing

VITALIZE.Use and Effectiveness of Sodium Zirconium Cyclosilicate (LokelmaTM) in the Real-world Setting in Spain

Who this might be right for
Hyperkalaemia
AstraZeneca 232
Testing effectiveness (Phase 2)Ended earlyNCT04983979
What this trial is testing

The ORTIZ Study: Optimising RASi Therapy With SZC

Who this might be right for
CKDDiabetes Mellitus, Type 2Hyperkalemia
Barts & The London NHS Trust 18
Post-approval studies (Phase 4)Looking for participantsNCT06365684
What this trial is testing

Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4

Who this might be right for
HyperkalemiaDiet ModificationChronic Kidney Disease+1 more
Leiden University Medical Center 16
Early research (Phase 1)Study completedNCT03283267
What this trial is testing

A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)

Who this might be right for
Hyperkalemia
AstraZeneca 22
Large-scale testing (Phase 3)Study completedNCT02163499
What this trial is testing

Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months

Who this might be right for
Hyperkalemia
ZS Pharma, Inc. 751
Not applicableStudy completedNCT06029179
What this trial is testing

SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients

Who this might be right for
Hyperkalemia
Alexandria University 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT04789239
What this trial is testing

OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure

Who this might be right for
Heart FailureHyperkalemia
Michael Fu 110
Testing effectiveness (Phase 2)Study completedNCT03337477
What this trial is testing

Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8

Who this might be right for
Hyperkalemia
AstraZeneca 70
Post-approval studies (Phase 4)Study completedNCT05535920
What this trial is testing

A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia

Who this might be right for
Hyperkalemia
NephroNet, Inc. 88
Post-approval studies (Phase 4)Study completedNCT05347693
What this trial is testing

Continuing Sodium Zirconium Cyclosilicate (SZC) After Discharge Study

Who this might be right for
HyperkalaemiaChronic Kidney Disease
AstraZeneca 186
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