Large-scale testing (Phase 3)UnknownNCT05310916What this trial is testingEffect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus PatientsWho this might be right forDiabetic Retinopathy Nidae Alaa 60
Not applicableStudy completedNCT07832409What this trial is testingCranberry Proanthocyanidins and Lactobacilli for Recurrent UTI Prevention in Type 2 DiabetesWho this might be right forType 2 Diabetes Mellitus (T2DM)Recurrent Urinary Tract Infections National Institute of Endocrinology, Georgia 100
Post-approval studies (Phase 4)Looking for participantsNCT07143773What this trial is testingSGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant RecipientsWho this might be right forKidney Transplantation RecipientsSodium-Glucose Transporter 2 InhibitorsNon-Diabetic Patients+2 more Odense University Hospital 88
Post-approval studies (Phase 4)Study completedNCT03982381What this trial is testingSGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 DiabetesWho this might be right forType 2 Diabetes Uppsala University 2,067
Large-scale testing (Phase 3)Study completedNCT06534411What this trial is testingA Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothWho this might be right forDiabetes Mellitus, Type 2 Novo Nordisk A/S 1,023
Testing effectiveness (Phase 2)Study completedNCT05884866What this trial is testingInvestigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease.Who this might be right forChronic Renal FailureMechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte HomeostatisChronic Kidney Disease Stage 3+1 more Klinikum Nürnberg
Post-approval studies (Phase 4)UnknownNCT05975528What this trial is testingEffect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 DiabetesWho this might be right forDiabetes MellitusCellular SenescenceSodium-Glucose Transporter 2 Inhibitors Yonsei University 92
Early research (Phase 1)Study completedNCT06828731What this trial is testingEvaluation of Empagliflozin vs Standard Care in Veterans With PrediabetesWho this might be right forPrediabetes Charles George VA Medical Center 60
Testing effectiveness (Phase 2)UnknownNCT04419337What this trial is testingPioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With StrokeWho this might be right forDiabetes MellitusStroke Chang Gung Memorial Hospital 200
Testing effectiveness (Phase 2)Study completedNCT03190694What this trial is testingEffects of Dapagliflozin in Non-diabetic Patients With ProteinuriaWho this might be right forChronic Kidney DiseasesProteinuria Hiddo Lambers Heerspink 53
Post-approval studies (Phase 4)Study completedNCT04196231What this trial is testingDurability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND)Who this might be right forType 2 Diabetes University of Campania Luigi Vanvitelli 258
Testing effectiveness (Phase 2)Looking for participantsNCT07336797What this trial is testingEffect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based TherapyWho this might be right forMetabolic SyndromeObesity & OverweightHIV (Human Immunodeficiency Virus) Abdelrahman Mahmoud 66
Not applicableActive Not RecruitingNCT07716774What this trial is testingSGLT-2 Inhibitors and Lower Urinary Tract SymptomsWho this might be right forSGLT2 InhibitorsLower Urinary Track SymptomsOveractive Bladder Marmara University 40
Large-scale testing (Phase 3)Not Yet RecruitingNCT06434025What this trial is testingIV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron DeficiencyWho this might be right forHeart Failure, SystolicIron Deficiencies Hospital de Clinicas de Porto Alegre 99
Early research (Phase 1)Study completedNCT05266404What this trial is testingPhase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single ComponentsWho this might be right forHealthy Volunteers (Intended Indication: Type 2 Diabetes Mellitus) AstraZeneca 46
Post-approval studies (Phase 4)Study completedNCT05309785What this trial is testingSafety and Efficacy of Canagliflozin in Advanced CKDWho this might be right forESRDCKD Stage 4CKD Stage 5 McGill University Health Centre/Research Institute of the McGill University Health Centre 34
Early research (Phase 1)Study completedNCT04201496What this trial is testingSGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes MellitusWho this might be right forType 1 Diabetes Ananda Basu, MD 34
Not applicableStudy completedNCT05164523What this trial is testingThe Effect of SGLT2 Inhibitors on Heart Rate Variability and BDNF Levels in Patients With Type 2 DiabetesWho this might be right forType 2 DiabetesHeart Rate Variability Goztepe Training and Research Hospital 64
Not applicableStudy completedNCT06453161What this trial is testingPre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery: a Retrospective Monocentric Cohort StudyWho this might be right forAcute Kidney InjuryCardiacSurgery Hospices Civils de Lyon 500
Post-approval studies (Phase 4)UnknownNCT02501616What this trial is testingEffect of Dapagliflozine on Systemic and Renal Endothelial FunctionWho this might be right forEndothelial FunctionType 2 Diabetes Seoul National University Hospital 22