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Results for “Sodium-glucose Co-transporter-2 Inhibitor”

42 trials

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Showing 20 of 42 results

Very early researchLooking for participantsNCT06430684
What this trial is testing

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

Who this might be right for
Chronic Kidney DiseasesPediatric Kidney Disease
Ann & Robert H Lurie Children's Hospital of Chicago 40
Large-scale testing (Phase 3)Looking for participantsNCT05392764
What this trial is testing

Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure

Who this might be right for
Acute Heart Failure
Juntendo University 444
Not applicableUnknownNCT06059287
What this trial is testing

The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

Who this might be right for
ObesityType 2 DiabetesSodium-glucose Co-transporter-2 Inhibitor+2 more
RenJi Hospital 64
Early research (Phase 1)Looking for participantsNCT05762952
What this trial is testing

Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease

Who this might be right for
Myocardial Ischemia
University of Virginia 40
Testing effectiveness (Phase 2)UnknownNCT05914857
What this trial is testing

Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients

Who this might be right for
Prediabetic StateImpaired Fasting GlucoseImpaired Glucose Tolerance
Yangjin 120
Post-approval studies (Phase 4)Study completedNCT02610088
What this trial is testing

Effect of Dapagliflozin on Vascular Functions in Patients With Type 2 Diabetes Compared to Gliclazide

Who this might be right for
Diabetes
Seoul National University Bundang Hospital 32
Not applicableStudy completedNCT02964572
What this trial is testing

Effect of Sodium Glucose Co-transporter 2 Inhibitor on Inflammatory Cytokine in Type 2 Diabetes

Who this might be right for
Type2 Diabetes Mellitus
Yonsei University 61
Large-scale testing (Phase 3)Looking for participantsNCT05345327
What this trial is testing

SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
The George Institute 994
Post-approval studies (Phase 4)Study completedNCT06374043
What this trial is testing

Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin.

Who this might be right for
Diabetes Mellitus, Type 2Diabetes Mellitus Type 2 With ProteinuriaDiabetes Mellitus+7 more
University Medical Center Groningen 20
Testing effectiveness (Phase 2)Study completedNCT04595370
What this trial is testing

Efficacy, Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease

Who this might be right for
Heart FailureChronic Kidney Disease
AstraZeneca 153
Post-approval studies (Phase 4)Study completedNCT06721442
What this trial is testing

Effect of Dapagliflozin on Electrocardiographic Parameters in Type 2 Diabetes Patients: DAPA - ECG Study

Who this might be right for
Arrhythmias, CardiacDiabetes Mellitus
Beneficência Portuguesa de São Paulo 174
Not applicableStudy completedNCT04061473
What this trial is testing

Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion

Who this might be right for
Diabetes After Total Pancreatectomy
University Hospital, Gentofte, Copenhagen 20
Testing effectiveness (Phase 2)Study completedNCT04724837
What this trial is testing

Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD Trial)

Who this might be right for
Chronic Kidney Disease
AstraZeneca 542
Not applicableUnknownNCT05103306
What this trial is testing

Empagliflozin-based Quadruple Therapy vs Basal Insulin-based Therapy

Who this might be right for
Diabetes Mellitus, Type 2
Chungbuk National University Hospital 300
Early research (Phase 1)Study completedNCT04201496
What this trial is testing

SGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes Mellitus

Who this might be right for
Type 1 Diabetes
Ananda Basu, MD 34
Post-approval studies (Phase 4)Ended earlyNCT05129722
What this trial is testing

Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial

Who this might be right for
Heart Failure With Preserved Ejection Fraction
The George Institute 3
Not applicableLooking for participantsNCT04591639
What this trial is testing

The DAPA-MEMRI Trial

Who this might be right for
Heart FailureDiabetic Cardiomyopathies
University of Edinburgh 160
Early research (Phase 1)Study completedNCT02404870
What this trial is testing

Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

Who this might be right for
Healthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 67
Early research (Phase 1)Study completedNCT03852901
What this trial is testing

Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production

Who this might be right for
EmpaglifozinPhysiological Effects of DrugsHypoglycemic Agents+1 more
National Institute on Aging (NIA) 21
Large-scale testing (Phase 3)Active Not RecruitingNCT06087835
What this trial is testing

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

Who this might be right for
Chronic Kidney Disease With High Proteinuria
AstraZeneca 1,835
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