Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Solid Neoplasms With NTRK Fusions”

29 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 29 results

Testing effectiveness (Phase 2)Looking for participantsNCT04996121
What this trial is testing

XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsLocally Advanced or Metastatic Non-small Cell Lung Cancer
Xuanzhu Biopharmaceutical Co., Ltd. 360
Early research (Phase 1)Study completedNCT02122913
What this trial is testing

Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT06390852
What this trial is testing

Testing LOXO-101 as Potentially Targeted Treatment in Cancers With NTRK Genetic Changes (MATCH - Subprotocol Z1E)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT03834961
What this trial is testing

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Who this might be right for
Central Nervous System NeoplasmInfantile FibrosarcomaRecurrent Acute Leukemia+2 more
Children's Oncology Group 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT02568267
What this trial is testing

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Who this might be right for
Breast CancerCholangiocarcinomaColorectal Cancer+13 more
Hoffmann-La Roche 534
Testing effectiveness (Phase 2)Study completedNCT02576431
What this trial is testing

Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 215
Not applicableStudy completedNCT06837090
What this trial is testing

Retrospective Analysis of the Experience With Larotrectinib in Patients With Solid Neoplasms With NTRK Fusion in Spain (SPAINTRK)

Who this might be right for
Solid Neoplasms With NTRK Fusions
Grupo Espanol de Tumores Neuroendocrinos 20
Early research (Phase 1)Study completedNCT02675491
What this trial is testing

Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Malignant Tumors
Daiichi Sankyo Co., Ltd. 15
Testing effectiveness (Phase 2)Looking for participantsNCT07394374
What this trial is testing

CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities

Who this might be right for
Solid Tumors Harboring NTRK FusionNTRKNTRK Gene Fusion+1 more
Cullgen (Shanghai),Inc 42
Not applicableNo Longer AvailableNCT03206931
What this trial is testing

Expanded Access to Provide Selitrectinib for the Treatment of Cancers With a NTRK Gene Fusion

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer
Not applicableActive Not RecruitingNCT06780384
What this trial is testing

NTRK 1,2,3 Rearrangements in Patients With Solid Tumors

Who this might be right for
NTRK1/2/3 Fusion Gene Detection
Federico Cappuzzo 5,000
Early research (Phase 1)Ended earlyNCT01804530
What this trial is testing

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorTumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion MutationsTenosynovial Giant Cell Tumor
Plexxikon 59
Testing effectiveness (Phase 2)Looking for participantsNCT06010342
What this trial is testing

Evaluate the Efficacy and Safety of TL118 in Solid Tumors Patients

Who this might be right for
Solid Tumor
Teligene US 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
Not applicableLooking for participantsNCT04142437
What this trial is testing

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

Who this might be right for
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Bayer 150
Not applicableStudy completedNCT04557813
What this trial is testing

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion

Who this might be right for
NTRK Family Gene Mutation
iOMEDICO AG 88
Testing effectiveness (Phase 2)Ended earlyNCT04617054
What this trial is testing

Phase II Study of AB-106 to Treat Patients With Solid Tumors With NTRK Gene Fusion

Who this might be right for
Solid Tumor
Nuvation Bio Inc. 14
Testing effectiveness (Phase 2)Looking for participantsNCT05745623
What this trial is testing

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Who this might be right for
Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd. 70
Early research (Phase 1)Ended earlyNCT04901806
What this trial is testing

Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors

Who this might be right for
Solid Tumor, AdultBrain Tumor, PrimaryDesmoplastic Small Round Cell Tumor
Pyramid Biosciences 29
Early research (Phase 1)UnknownNCT04687423
What this trial is testing

Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）

Who this might be right for
Advanced Solid Tumor
Fochon Pharmaceuticals, Ltd. 82
Load More Results