Testing effectiveness (Phase 2)UnknownNCT04744532What this trial is testingIPSC-based Drug Repurposing for ALS Medicine (iDReAM) StudyWho this might be right forAmyotrophic Lateral Sclerosis Kyoto University 49
Testing effectiveness (Phase 2)Study completedNCT03204500What this trial is testingDual Treatment With Lithium and Valproate in ALS.Who this might be right forAmyotrophic Lateral SclerosisAmyotrophic Lateral Sclerosis, Sporadic El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez 43
Testing effectiveness (Phase 2)Study completedNCT02781454What this trial is testingMexiletine in Sporadic Amyotrophic Lateral SclerosisWho this might be right forSporadic Amyotrophic Lateral Sclerosis University of Washington 20
Early research (Phase 1)Looking for participantsNCT07100119What this trial is testingLY4256984 in Participants With Sporadic Amyotrophic Lateral SclerosisWho this might be right forALS (Amyotrophic Lateral Sclerosis) Eli Lilly and Company 32
Not applicableLooking for participantsNCT05928416What this trial is testingALS Diagnosis From a Saliva Sample: a Non-coding RNA Analysis ApproachWho this might be right forAmyotrophic Lateral Sclerosis, SporadicAmyotrophic Lateral Sclerosis ZIWIG 600
Not applicableWithdrawnNCT01459302What this trial is testingGenetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular DisordersWho this might be right forAmyotrophic Lateral SclerosisFrontotemporal DementiaPLS+7 more University of Massachusetts, Worcester
Not applicableStudy completedNCT00015444What this trial is testingScreening and Natural History: Primary Lateral Sclerosis and Related DisordersWho this might be right forPrimary Lateral Sclerosis National Institute of Neurological Disorders and Stroke (NINDS) 189
Early research (Phase 1)Ended earlyNCT06215755What this trial is testingVRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Verge Genomics 54
Not applicableTemporarily pausedNCT03449212What this trial is testingSOD1 Kinetics Measurements in ALS PatientsWho this might be right forAmyotrophic Lateral Sclerosis, FamilialAmyotrophic Lateral Sclerosis, Sporadic Washington University School of Medicine 86
Not applicableStudy completedNCT05852405What this trial is testingClinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALSWho this might be right forMotor Neuron Disease, Amyotrophic Lateral Sclerosis Ambulanzpartner Soziotechnologie APST GmbH 2,000
Testing effectiveness (Phase 2)Study completedNCT01849770What this trial is testingMexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)Who this might be right forSporadic Amyotrophic Lateral Sclerosis University of Washington 75
Not applicableStudy completedNCT00821132What this trial is testingGenetics of Familial and Sporadic ALSWho this might be right forAmyotrophic Lateral Sclerosis (ALS)Familial Amyotrophic Lateral SclerosisALS With Frontotemporal Dementia (ALS/FTD)+4 more Northwestern University 13,521
Early research (Phase 1)Looking for participantsNCT06665165What this trial is testingAMX0114 in Adult Participants With Amyotrophic Lateral SclerosisWho this might be right forALS Amylyx Pharmaceuticals Inc. 48
Testing effectiveness (Phase 2)Study completedNCT05039099What this trial is testingEvaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis AL-S Pharma 73
Very early researchUnknownNCT02969759What this trial is testingBioenergetics and Protein Metabolism in Sporadic Amyotrophic Lateral SclerosisWho this might be right forSporadic Amyotrophic Lateral Sclerosis University Hospital, Angers 30
Not applicableStudy completedNCT02686268What this trial is testingUnderstanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALSWho this might be right forC9ORF72 Amyotrophic Lateral Sclerosis (ALS) Washington University School of Medicine 128
Testing effectiveness (Phase 2)Study completedNCT03019419What this trial is testingPerampanel for Sporadic Amyotrophic Lateral Sclerosis (ALS)Who this might be right forALS Tokyo Medical University 66
Post-approval studies (Phase 4)Looking for participantsNCT05923905What this trial is testingClinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS PatientsWho this might be right forSporadic and Familial Amyotrophic Lateral Sclerosis Peking University Third Hospital 64
Early research (Phase 1)UnknownNCT03981536What this trial is testingEvaluate AP-101 in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis AL-S Pharma 18