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Results for “Squamous Carcinoma of the Head and Neck (Human Papillomavirus (HPV) Negative)”

14 trials

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Showing 14 of 14 results

Testing effectiveness (Phase 2)Study completedNCT02207439
What this trial is testing

Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 18
Early research (Phase 1)Study completedNCT03096054
What this trial is testing

A Phase I Trial of LY3143921 Hydrate in Solid Tumours

Who this might be right for
Colorectal CancerHigh Grade Serous Ovarian CancerNon Small-cell Lung Cancer (Squamous Cell Variant)+4 more
Cancer Research UK 69
Testing effectiveness (Phase 2)Looking for participantsNCT06636734
What this trial is testing

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown PrimaryMetastatic Head and Neck Squamous Cell Carcinoma+19 more
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT07513389
What this trial is testing

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

Who this might be right for
Squamous Cell CarcinomaHuman Papilloma Virus (HPV)Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Medical University of South Carolina 36
Early research (Phase 1)WithdrawnNCT02686008
What this trial is testing

Pharmacodynamic Study to Assess the Anti-proliferative Activity of the PARP Inhibitor Olaparib in Patients With HPV Positive and HPV Negative HNSCC

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Yale University
Early research (Phase 1)Looking for participantsNCT06997094
What this trial is testing

Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer

Who this might be right for
Human Papillomavirus-Negative Neck Squamous Cell CarcinomaResectable Head and Neck Squamous Cell CarcinomaResectable Human Papillomavirus-Independent Head and Neck Mucosal Squamous Cell Carcinoma+2 more
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Testing effectiveness (Phase 2)Study completedNCT03944915
What this trial is testing

De-Escalation Therapy for Human Papillomavirus Negative Disease

Who this might be right for
Human Papilloma VirusSquamous Cell CarcinomaSquamous Cell Carcinoma of the Head and Neck+2 more
University of Chicago 35
Testing effectiveness (Phase 2)Ended earlyNCT02540928
What this trial is testing

AMG 319 in HPV Positive and Negative HNSCC

Who this might be right for
Human Papillomavirus (HPV)Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
Cancer Research UK 35
Testing effectiveness (Phase 2)Study completedNCT02499120
What this trial is testing

Safety And Efficacy Study Of Palbociclib Plus Cetuximab Versus Cetuximab To Treat Head And Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Pfizer 125
Testing effectiveness (Phase 2)Study completedNCT01807546
What this trial is testing

Oral Rigosertib for Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell CarcinomaAnal Squamous Cell CarcinomaLung Squamous Cell Carcinoma+4 more
Traws Pharma, Inc. 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03323463
What this trial is testing

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

Who this might be right for
HPV-Associated Oropharyngeal Squamous Cell CarcinomaSquamous Cell Carcinoma of the Neck
Memorial Sloan Kettering Cancer Center 316
Very early researchEnded earlyNCT02827838
What this trial is testing

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

Who this might be right for
Human Papillomavirus InfectionStage I Oral Cavity Squamous Cell CarcinomaStage I Oropharyngeal Squamous Cell Carcinoma+9 more
Wake Forest University Health Sciences 17
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