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Results for “Stage IV Merkel Cell Carcinoma”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04792073
What this trial is testing

Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma

Who this might be right for
Merkel Cell Carcinoma
Memorial Sloan Kettering Cancer Center 18
Not applicableStudy completedNCT04670445
What this trial is testing

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

Who this might be right for
Stage IV MelanomaAdvanced Lung CancerStage IV Non-Small Cell Lung Cancer+19 more
Massachusetts General Hospital 199
Testing effectiveness (Phase 2)Study completedNCT03304639
What this trial is testing

Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma

Who this might be right for
Advanced Merkel Cell CarcinomaClinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Testing effectiveness (Phase 2)Ended earlyNCT03747484
What this trial is testing

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Who this might be right for
Other Skin
Fred Hutchinson Cancer Center 7
Early research (Phase 1)WithdrawnNCT02831179
What this trial is testing

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Who this might be right for
Functional Pancreatic Neuroendocrine TumorMalignant SomatostatinomaMerkel Cell Carcinoma+26 more
Vanderbilt-Ingram Cancer Center
Not applicableAvailableNCT04853602
What this trial is testing

IFx-Hu2.0 Expanded Access Program

Who this might be right for
Cutaneous Melanoma, Stage IIICutaneous Melanoma, Stage IVMerkel Cell Carcinoma+1 more
TuHURA Biosciences, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Ended earlyNCT02465957
What this trial is testing

QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)

Who this might be right for
Stage IIIB Merkel Cell CarcinomaStage IV Merkel Cell Carcinoma
ImmunityBio, Inc. 7
Testing effectiveness (Phase 2)Study completedNCT00079131
What this trial is testing

Oblimersen in Treating Patients With Merkel Cell Carcinoma

Who this might be right for
Recurrent Neuroendocrine Carcinoma of the SkinStage I Neuroendocrine Carcinoma of the SkinStage II Neuroendocrine Carcinoma of the Skin+2 more
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Ended earlyNCT02584829
What this trial is testing

Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma

Who this might be right for
Merkel Cell Polyomavirus InfectionStage IV Merkel Cell Carcinoma AJCC v7
Fred Hutchinson Cancer Center 8
Testing effectiveness (Phase 2)Ended earlyNCT01758458
What this trial is testing

Viral Oncoprotein Targeted Autologous T Cell Therapy for Merkel Cell Carcinoma

Who this might be right for
Recurrent Merkel Cell CarcinomaStage IV Merkel Cell Carcinoma
Fred Hutchinson Cancer Center 4
Testing effectiveness (Phase 2)Study completedNCT02267603
What this trial is testing

Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer

Who this might be right for
Recurrent Merkel Cell CarcinomaStage III Merkel Cell Carcinoma AJCC v7Stage IIIA Merkel Cell Carcinoma AJCC v7+2 more
National Cancer Institute (NCI) 50
Testing effectiveness (Phase 2)Looking for participantsNCT05896839
What this trial is testing

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+10 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07472322
What this trial is testing

ASTX727 & Retifanlimab-dlwr for Advanced Merkel Cell After Progression on Anti-PD-(L)1

Who this might be right for
Merkel Cell CarcinomaMerkel Cell Carcinoma, Stage IIIMerkel Cell Carcinoma, Stage IV
University of Wisconsin, Madison 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056895
What this trial is testing

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Who this might be right for
Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8Clinical Stage IV Merkel Cell Carcinoma AJCC v8Merkel Cell Carcinoma
University of Washington 12
Not applicableLooking for participantsNCT07215988
What this trial is testing

Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

Who this might be right for
Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
Ohio State University Comprehensive Cancer Center 70
Early research (Phase 1)Looking for participantsNCT06444815
What this trial is testing

VET3-TGI in Patients With Solid Tumors

Who this might be right for
Solid Tumor, AdultMicrosatellite Stable Colorectal CancerHead and Neck Squamous Cell Carcinoma+10 more
KaliVir Immunotherapeutics 60
Early research (Phase 1)Study completedNCT01155258
What this trial is testing

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

Who this might be right for
Extensive Stage Small Cell Lung CancerHereditary ParagangliomaMale Breast Cancer+45 more
University of Southern California 19
Early research (Phase 1)Study completedNCT00655655
What this trial is testing

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

Who this might be right for
GastrinomaGlucagonomaInsulinoma+17 more
Mayo Clinic 96
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