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Results for “Stage IV Merkel Cell Carcinoma”

26 trials

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Showing 20 of 26 results

Early research (Phase 1)Active Not RecruitingNCT03816332
What this trial is testing

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+18 more
National Cancer Institute (NCI) 12
Testing effectiveness (Phase 2)Study completedNCT02267603
What this trial is testing

Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer

Who this might be right for
Recurrent Merkel Cell CarcinomaStage III Merkel Cell Carcinoma AJCC v7Stage IIIA Merkel Cell Carcinoma AJCC v7+2 more
National Cancer Institute (NCI) 50
Testing effectiveness (Phase 2)Ended earlyNCT02584829
What this trial is testing

Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma

Who this might be right for
Merkel Cell Polyomavirus InfectionStage IV Merkel Cell Carcinoma AJCC v7
Fred Hutchinson Cancer Center 8
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+127 more
Mayo Clinic 36
Early research (Phase 1)Active Not RecruitingNCT04616248
What this trial is testing

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8+10 more
University of Southern California 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT04792073
What this trial is testing

Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma

Who this might be right for
Merkel Cell Carcinoma
Memorial Sloan Kettering Cancer Center 18
Not applicableLooking for participantsNCT07215988
What this trial is testing

Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

Who this might be right for
Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
Ohio State University Comprehensive Cancer Center 70
Early research (Phase 1)Study completedNCT01155258
What this trial is testing

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

Who this might be right for
Extensive Stage Small Cell Lung CancerHereditary ParagangliomaMale Breast Cancer+45 more
University of Southern California 19
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Study completedNCT02643303
What this trial is testing

Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Who this might be right for
Head and Neck Squamous Cell CarcinomaBreast CancerSarcoma+8 more
Ludwig Institute for Cancer Research 58
Testing effectiveness (Phase 2)Ended earlyNCT03747484
What this trial is testing

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Who this might be right for
Other Skin
Fred Hutchinson Cancer Center 7
Testing effectiveness (Phase 2)Looking for participantsNCT05896839
What this trial is testing

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+10 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT03074513
What this trial is testing

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Who this might be right for
Appendix AdenocarcinomaHuman Papillomavirus-Related Anal Squamous Cell CarcinomaHuman Papillomavirus-Related Cervical Squamous Cell Carcinoma+18 more
M.D. Anderson Cancer Center 133
Testing effectiveness (Phase 2)Ended earlyNCT01758458
What this trial is testing

Viral Oncoprotein Targeted Autologous T Cell Therapy for Merkel Cell Carcinoma

Who this might be right for
Recurrent Merkel Cell CarcinomaStage IV Merkel Cell Carcinoma
Fred Hutchinson Cancer Center 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056895
What this trial is testing

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Who this might be right for
Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8Clinical Stage IV Merkel Cell Carcinoma AJCC v8Merkel Cell Carcinoma
University of Washington 12
Early research (Phase 1)Study completedNCT01204476
What this trial is testing

Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

Who this might be right for
Gastrin-Producing Neuroendocrine TumorLung Carcinoid TumorMetastatic Digestive System Neuroendocrine Tumor G1+12 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Active Not RecruitingNCT05947500
What this trial is testing

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Who this might be right for
Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8Locally Advanced Merkel Cell Carcinoma+3 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT02465957
What this trial is testing

QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)

Who this might be right for
Stage IIIB Merkel Cell CarcinomaStage IV Merkel Cell Carcinoma
ImmunityBio, Inc. 7
Early research (Phase 1)Ended earlyNCT00002947
What this trial is testing

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Langerhans Cell HistiocytosisGastrointestinal Carcinoid Tumor+9 more
Yale University 35
Not applicableUnknownNCT04670445
What this trial is testing

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

Who this might be right for
Stage IV MelanomaAdvanced Lung CancerStage IV Non-Small Cell Lung Cancer+19 more
Massachusetts General Hospital 210
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