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Results for “Subjects With High LDL-Cholesterol”

55 trials

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Showing 20 of 55 results

Large-scale testing (Phase 3)Study completedNCT00812955
What this trial is testing

Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and Triglycerides

Who this might be right for
Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia
AstraZeneca 474
Testing effectiveness (Phase 2)Study completedNCT00158899
What this trial is testing

GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol

Who this might be right for
DyslipidaemiasDyslipidaemia
GlaxoSmithKline 424
Early research (Phase 1)Study completedNCT01671085
What this trial is testing

LY3015014 in Healthy Participants With High Cholesterol

Who this might be right for
Healthy VolunteersHypercholesterolemia
Eli Lilly and Company 13
Early research (Phase 1)Study completedNCT01487460
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAP311 in Healthy Subjects and Dyslipidemic Patients

Who this might be right for
DyslipidemiaHealthy Volunteers
Novartis Pharmaceuticals 137
Large-scale testing (Phase 3)Study completedNCT00239330
What this trial is testing

Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin Therapy

Who this might be right for
Hypercholesteremia
AstraZeneca 824
Large-scale testing (Phase 3)Study completedNCT03400800
What this trial is testing

Inclisiran for Subjects With ASCVD or ASCVD-Risk Equivalents and Elevated Low-density Lipoprotein Cholesterol

Who this might be right for
ASCVDRisk Factor, CardiovascularElevated Cholesterol
The Medicines Company 1,617
Early research (Phase 1)Not Yet RecruitingNCT07074236
What this trial is testing

Pharmacokinetics and Pharmacodynamics Study

Who this might be right for
Primary Hypercholesterolemia or Combined Hyperlipidemia Characterized by Elevated LDL-C
Qilu Pharmaceutical Co., Ltd. 48
Early research (Phase 1)Study completedNCT01426412
What this trial is testing

LY3015014 in Healthy Participants With Elevated Low Density Lipoprotein Cholesterol

Who this might be right for
Hyperlipidemia
Eli Lilly and Company 69
Early research (Phase 1)WithdrawnNCT01163838
What this trial is testing

Multiple-Dose Safety Study Of RN316 For TheTreatment Of Hypercholesterolemia

Who this might be right for
HypercholesterolemiaDyslipidemia
Pfizer
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Early research (Phase 1)Study completedNCT05896969
What this trial is testing

Dose Escalation of SNK-396 in Participants With Elevated Low-Density Lipoprotein Cholesterol

Who this might be right for
Elevated Low-Density Lipoprotein Cholesterol
Syneos Health 41
Testing effectiveness (Phase 2)Study completedNCT02597127
What this trial is testing

Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial HypercholesterolemiaDiabetes
The Medicines Company 501
Early research (Phase 1)Study completedNCT06229548
What this trial is testing

A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SYH2053

Who this might be right for
Hyperlipemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 39
Large-scale testing (Phase 3)Study completedNCT01879319
What this trial is testing

Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen

Who this might be right for
Primary HypercholesterolemiaMixed Dyslipidemia
Amgen 164
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Not applicableStudy completedNCT00114855
What this trial is testing

The Effect of Hypocol® on Lipids in Subjects With Mild Hypercholesterolemia and Mildly Elevated Blood Glucose

Who this might be right for
HyperlipidemiaGlucose Metabolism Disorders
Oslo University Hospital 40
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Testing effectiveness (Phase 2)Study completedNCT03531905
What this trial is testing

Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C

Who this might be right for
DiabetesDiabetes Mellitus, Type 2Cholesterolemia
Esperion Therapeutics, Inc. 242
Testing effectiveness (Phase 2)Study completedNCT00216463
What this trial is testing

Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels

Who this might be right for
Hypercholesterolemia
Kastle Therapeutics, LLC 50
Early research (Phase 1)Study completedNCT01618916
What this trial is testing

LY3015014 in Otherwise Healthy Participants With High Low-density Lipoprotein (LDL) Cholesterol

Who this might be right for
Healthy Volunteers
Eli Lilly and Company 51
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