Testing effectiveness (Phase 2)UnknownNCT04426578What this trial is testingRole of Perhexiline in Hypertrophic CardiomyopathyWho this might be right forHypertrophic Cardiomyopathy Flinders University 60
Not applicableLooking for participantsNCT06146660What this trial is testingAssess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic CardiomyopathyWho this might be right forObstructive Hypertrophic Cardiomyopathy Bristol-Myers Squibb 600
Post-approval studies (Phase 4)Looking for participantsNCT07004972What this trial is testingMavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)Who this might be right forSymptomatic Obstructive Hypertrophic Cardiomyopathy Bristol-Myers Squibb 50
Large-scale testing (Phase 3)Study completedNCT04349072What this trial is testingEvaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction TherapyWho this might be right forHOCM, Hypertrophic Obstructive Cardiomyopathy Bristol-Myers Squibb 112
Not applicableActive Not RecruitingNCT05648825What this trial is testingTransapical Beating-Heart Septal Myectomy for Symptomatic Nonobstructive Hypertrophic CardiomyopathyWho this might be right forNonobstructive Hypertrophic Cardiomyopathy Xiang Wei 100
Not applicableUnknownNCT05771987What this trial is testingPermanent Pacing for Drug-refractory Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.Who this might be right forObstructive Hypertrophic Cardiomyopathy Istituto Auxologico Italiano 10
Large-scale testing (Phase 3)Study completedNCT05414175What this trial is testingMavacamten in Obstructive Hypertrophic CardiomyopathyWho this might be right forCardiomyopathy, Hypertrophic Obstructive Bristol-Myers Squibb 38
Testing effectiveness (Phase 2)Study completedNCT03442764What this trial is testingMavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)Who this might be right forNon-obstructive Hypertrophic Cardiomyopathy MyoKardia, Inc. 59
Not applicableActive Not RecruitingNCT06372457What this trial is testingCOLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)Who this might be right forHypertrophic Cardiomyopathy (HCM) Bristol-Myers Squibb 500
Large-scale testing (Phase 3)Looking for participantsNCT06481891What this trial is testingEvaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyWho this might be right forObstructive Cardiomyopathy, HypertrophicNon-obstructive Hypertrophic Cardiomyopathy Lexicon Pharmaceuticals 500
Large-scale testing (Phase 3)Active Not RecruitingNCT06081894What this trial is testingPhase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCMWho this might be right forSymptomatic Non-Obstructive Hypertrophic Cardiomyopathy Cytokinetics 500
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743What this trial is testingEvaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic CardiomyopathyWho this might be right forCardiomyopathy, Hypertrophic Bristol-Myers Squibb 63
Testing effectiveness (Phase 2)Study completedNCT00001960What this trial is testingStudying the Effectiveness of Pacemaker Therapy in Children Who Have Thickened Heart MuscleWho this might be right forHypertrophic Cardiomyopathy National Heart, Lung, and Blood Institute (NHLBI) 50
Testing effectiveness (Phase 2)Study completedNCT03496168What this trial is testingExtension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEERWho this might be right forHypertrophic Cardiomyopathy Bristol-Myers Squibb 13
Large-scale testing (Phase 3)Study completedNCT06116968What this trial is testingAn Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCMWho this might be right forObstructive Hypertrophic Cardiomyopathy Corxel Pharmaceuticals 40
Large-scale testing (Phase 3)Looking for participantsNCT07023341What this trial is testingLearn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic CardiomyopathyWho this might be right forObstructive Hypertrophic Cardiomyopathy Bayer 34
Large-scale testing (Phase 3)Study completedNCT05582395What this trial is testingMavacamten in Non-Obstructive Hypertrophic CardiomyopathyWho this might be right forCardiomyopathy, Hypertrophic Bristol-Myers Squibb 580
Testing effectiveness (Phase 2)Study completedNCT04219826What this trial is testingDose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCMWho this might be right forHypertrophic Cardiomyopathy (HCM) Cytokinetics 96
Not applicableEnded earlyNCT06775886What this trial is testingEffect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic CardiomyopathyWho this might be right forNon-obstructive Hypertrophic CardiomyopathyHypertrophic Cardiomyopathy Montefiore Medical Center 1
Not applicableStudy completedNCT03450252What this trial is testingPacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic CardiomyopathyWho this might be right forCardiomyopathy, Hypertrophic Barts & The London NHS Trust 17