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Results for “Symptomatic Hypertrophic Cardiomyopathy (HCM)”

45 trials

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Showing 20 of 45 results

Large-scale testing (Phase 3)Study completedNCT06116968
What this trial is testing

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Corxel Pharmaceuticals 40
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Post-approval studies (Phase 4)Looking for participantsNCT05569382
What this trial is testing

Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
Morten Steen Kvistholm Jensen 100
Large-scale testing (Phase 3)Study completedNCT03723655
What this trial is testing

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Who this might be right for
Hypertrophic CardiomyopathyObstructive Hypertrophic CardiomyopathyNon-obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 314
Not applicableStudy completedNCT03450252
What this trial is testing

Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Barts & The London NHS Trust 17
Not applicableActive Not RecruitingNCT06947590
What this trial is testing

Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
HCM - Hypertrophic CardiomyopathyMavacamten
Xu Liu 78
Early research (Phase 1)Study completedNCT03767855
What this trial is testing

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Who this might be right for
Symptomatic Obstructive Hypertrophic CardiomyopathyHealthy Subjects
Cytokinetics 114
Testing effectiveness (Phase 2)Study completedNCT00001960
What this trial is testing

Studying the Effectiveness of Pacemaker Therapy in Children Who Have Thickened Heart Muscle

Who this might be right for
Hypertrophic Cardiomyopathy
National Heart, Lung, and Blood Institute (NHLBI) 50
Not applicableNot Yet RecruitingNCT06856265
What this trial is testing

Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic CardiomyopathyMavacamtenRadiofrequency Ablation
Shanghai Chest Hospital 40
Not applicableEnded earlyNCT06775886
What this trial is testing

Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic CardiomyopathyHypertrophic Cardiomyopathy
Montefiore Medical Center 1
Testing effectiveness (Phase 2)Study completedNCT03496168
What this trial is testing

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 13
Not applicableActive Not RecruitingNCT05648825
What this trial is testing

Transapical Beating-Heart Septal Myectomy for Symptomatic Nonobstructive Hypertrophic Cardiomyopathy

Who this might be right for
Nonobstructive Hypertrophic Cardiomyopathy
Xiang Wei 100
Testing effectiveness (Phase 2)Study completedNCT03442764
What this trial is testing

Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 59
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07675668
What this trial is testing

Aom0304 in Adult Patients With Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Obstructive HCM (oHCM)Non-obstructive HCM (nHCM)
Amckaus PTY LTD. 56
Post-approval studies (Phase 4)Not Yet RecruitingNCT07807384
What this trial is testing

Efficacy and Safety of an LVEF-Guided Mavacamten Dose Up-Titration Strategy in Chinese Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Second Affiliated Hospital of Nanchang University 115
Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Testing effectiveness (Phase 2)UnknownNCT04426578
What this trial is testing

Role of Perhexiline in Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy
Flinders University 60
Large-scale testing (Phase 3)Study completedNCT05186818
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 282
Large-scale testing (Phase 3)Study completedNCT03470545
What this trial is testing

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 251
Post-approval studies (Phase 4)Active Not RecruitingNCT07004972
What this trial is testing

Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Who this might be right for
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 50
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