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Results for “TGF-β”

48 trials

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Showing 20 of 48 results

Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Early research (Phase 1)Looking for participantsNCT06487624
What this trial is testing

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Who this might be right for
Advanced Solid TumorRefractory Hodgkin Lymphoma
FBD Biologics Limited 50
Early research (Phase 1)Active Not RecruitingNCT05717348
What this trial is testing

ES014 in Patients With Locally Advanced or Metastatic Solid Tumours

Who this might be right for
Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor
Elpiscience (Suzhou) Biopharma, Ltd. 120
Not applicableStudy completedNCT07407101
What this trial is testing

Impact of Filtration on Autologous Serum Eye Drops

Who this might be right for
Dry Eye Syndrome (DES)
University Hospital, Limoges 10
Not applicableStudy completedNCT00536705
What this trial is testing

Effect of Montelukast on the Expression and Variation of TGF-β for Children With Mild Persistent Asthma

Who this might be right for
Asthma
Shanghai Jiao Tong University School of Medicine 112
Testing effectiveness (Phase 2)Study completedNCT04246489
What this trial is testing

Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer

Who this might be right for
Uterine Cervical Neoplasms
EMD Serono Research & Development Institute, Inc. 146
Testing effectiveness (Phase 2)UnknownNCT05785728
What this trial is testing

DB-1202 Monotherapy in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
DualityBio Inc. 150
Not applicableUnknownNCT01668381
What this trial is testing

Enumeration and Function Analysis of Treg Cells in Peripheral Blood of HCC Patients Before and After Ablation Therapy

Who this might be right for
Hepatocellular Carcinoma
First Affiliated Hospital, Sun Yat-Sen University 20
Not applicableLooking for participantsNCT07661784
What this trial is testing

Salivary Biomarkers in Periodontal Disease Progression

Who this might be right for
Periodontal DiseaseGingivitis and Periodontal DiseasesPeriodontitis
Suleyman Demirel University 240
Testing effectiveness (Phase 2)Looking for participantsNCT06543056
What this trial is testing

ES014 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 15
Testing effectiveness (Phase 2)Ended earlyNCT04428047
What this trial is testing

Evaluation of Bintrafusp Alfa in Operable and Untreated Head and Neck Squamous Cell Carcinoma

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
UNICANCER 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT02452008
What this trial is testing

Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

Who this might be right for
Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 60
Large-scale testing (Phase 3)WithdrawnNCT01361087
What this trial is testing

Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome

Who this might be right for
Marfan Syndrome
Ann & Robert H Lurie Children's Hospital of Chicago
Not applicableNot Yet RecruitingNCT07769866
What this trial is testing

Retlirafusp Alfa Combined With Chemoradiotherapy in Unresectable ESCC

Who this might be right for
Esophageal Squamous Cell Cancer
RenJi Hospital 68
Early research (Phase 1)Study completedNCT05028556
What this trial is testing

A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors

Who this might be right for
Metastatic or Locally Advanced Solid Tumors
Wuhan YZY Biopharma Co., Ltd. 50
Not applicableUnknownNCT05218122
What this trial is testing

Characteristics of LKDS and PBSS of KOA Based on the Enhancement of Inflammatory Response by TGF-β/Smad Pathway Inhibited

Who this might be right for
Knee OsteoarthritisSyndromeTraditional Chinese Medicine
Dongzhimen Hospital, Beijing 340
Early research (Phase 1)Study completedNCT05653284
What this trial is testing

AK130 in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
Akeso 19
Not applicableStudy completedNCT06604390
What this trial is testing

THE EFFECTS OF GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION ON COGNITIVE FUNCTION, EXPRESSION OF APP, MAPT, BDNF, IL-10, TGF-Β GENES, AND PLASMA MDA LEVELS IN THE ELDERLY.

Who this might be right for
Elderly Individuals Aged 60 Years or OlderMild Cognitive Impairment (MCI)
Rahmi Novita Yusuf 64
Early research (Phase 1)Ended earlyNCT04729725
What this trial is testing

SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
M.D. Anderson Cancer Center 3
Early research (Phase 1)Active Not RecruitingNCT07474168
What this trial is testing

T Cell Receptor Gene-Engineered and Dominant Negative TGF-β Receptor T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Who this might be right for
Tumor
Zhejiang University 9
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