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Results for “TGF-β”

41 trials

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Showing 20 of 41 results

Not applicableStudy completedNCT06604390
What this trial is testing

The EFFECTS of GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION on COGNITIVE FUNCTION, EXPRESSION of APP, MAPT, BDNF, IL-10, TGF-Β GENES, and PLASMA MDA LEVELS in the ELDERLY.

Who this might be right for
Elderly Individuals Aged 60 Years or OlderMild Cognitive Impairment (MCI)
Rahmi Novita Yusuf 64
Testing effectiveness (Phase 2)Study completedNCT04246489
What this trial is testing

Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer

Who this might be right for
Uterine Cervical Neoplasms
EMD Serono Research & Development Institute, Inc. 146
Not applicableStudy completedNCT07029035
What this trial is testing

Evaluation of Repeated Injectable PRF Following SRP in Patients With Periodontitis

Who this might be right for
Periodontitis Stage III
Saglik Bilimleri Universitesi 20
Not applicableUnknownNCT01668381
What this trial is testing

Enumeration and Function Analysis of Treg Cells in Peripheral Blood of HCC Patients Before and After Ablation Therapy

Who this might be right for
Hepatocellular Carcinoma
First Affiliated Hospital, Sun Yat-Sen University 20
Large-scale testing (Phase 3)WithdrawnNCT01361087
What this trial is testing

Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome

Who this might be right for
Marfan Syndrome
Ann & Robert H Lurie Children's Hospital of Chicago
Testing effectiveness (Phase 2)Ended earlyNCT04952753
What this trial is testing

Study of NIS793 and Other Novel Investigational Combinations With SOC Anti-cancer Therapy for the 2L Treatment of mCRC

Who this might be right for
Metastatic Colorectal Cancer
Novartis Pharmaceuticals 204
Early research (Phase 1)Study completedNCT02734160
What this trial is testing

Galunisertib (LY2157299) and Durvalumab (MEDI4736) in Participants With Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Cancer
Eli Lilly and Company 37
Not applicableLooking for participantsNCT06683690
What this trial is testing

TGF β 1 Expression Related Gene Polymorphism

Who this might be right for
Leprosy
Aswan University 60
Early research (Phase 1)Study completedNCT05653284
What this trial is testing

AK130 in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
Akeso 19
Early research (Phase 1)Study completedNCT05028556
What this trial is testing

A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors

Who this might be right for
Metastatic or Locally Advanced Solid Tumors
Wuhan YZY Biopharma Co., Ltd. 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT07321860
What this trial is testing

This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic Signaling

Who this might be right for
ALS (Amyotrophic Lateral Sclerosis)
Gipfel Life Sciences GmbH 60
Early research (Phase 1)Active Not RecruitingNCT05717348
What this trial is testing

ES014 in Patients With Locally Advanced or Metastatic Solid Tumours

Who this might be right for
Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor
Elpiscience (Suzhou) Biopharma, Ltd. 120
Early research (Phase 1)Ended earlyNCT04729725
What this trial is testing

SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
M.D. Anderson Cancer Center 3
Early research (Phase 1)Looking for participantsNCT06487624
What this trial is testing

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Who this might be right for
Advanced Solid TumorRefractory Hodgkin Lymphoma
FBD Biologics Limited 50
Not applicableLooking for participantsNCT04481256
What this trial is testing

TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY

Who this might be right for
Carcinoma, Squamous CellOesophageal Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 49
Not applicableLooking for participantsNCT06426953
What this trial is testing

Predictive Effect of TGF-β and INS-PI3K-AKT Related Proteins for POD in Diabetes Patients

Who this might be right for
DiabetesPostoperative Delirium
Xie Kangjie 180
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05425576
What this trial is testing

OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition

Who this might be right for
Malignant Pleural Mesothelioma
Oncotelic Inc. 63
Not applicableActive Not RecruitingNCT06749119
What this trial is testing

The Effects of Age on Wound Healing on Free Gingival Graft Surgery in the Treatment of Attached Keratinized Gingival Deficiency by Determining Clinical and Biochemical Outcomes

Who this might be right for
Wound HealingTissue GraftsAge+2 more
Marmara University 30
Not applicableUnknownNCT05218122
What this trial is testing

Characteristics of LKDS and PBSS of KOA Based on the Enhancement of Inflammatory Response by TGF-β/Smad Pathway Inhibited

Who this might be right for
Knee OsteoarthritisSyndromeTraditional Chinese Medicine
Dongzhimen Hospital, Beijing 340
Not applicableLooking for participantsNCT04998227
What this trial is testing

Latent TGF-β-binding Proteins Affect the Fibrotic Process in Renal Impairment and Cardiac Dysfunction

Who this might be right for
Acute Coronary SyndromeAcute Coronary Syndrome With Renal Dysfunction
National Taiwan University Hospital 300
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