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Results for “TGF-β”

42 trials

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Showing 20 of 42 results

Early research (Phase 1)Study completedNCT02160106
What this trial is testing

First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors

Who this might be right for
Advanced Stage Solid Tumors
MedPacto, Inc. 35
Testing effectiveness (Phase 2)Ended earlyNCT04489940
What this trial is testing

Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast Neoplasms
EMD Serono Research & Development Institute, Inc. 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT05077800
What this trial is testing

FOLFIRINOX + Elraglusib + Losartan In Pancreatic Cancer

Who this might be right for
Pancreatic AdenocarcinomaPancreatic Adenocarcinoma Metastatic
Colin D. Weekes, M.D., PhD 70
Not applicableLooking for participantsNCT06683690
What this trial is testing

TGF β 1 Expression Related Gene Polymorphism

Who this might be right for
Leprosy
Aswan University 60
Not applicableUnknownNCT05218122
What this trial is testing

Characteristics of LKDS and PBSS of KOA Based on the Enhancement of Inflammatory Response by TGF-β/Smad Pathway Inhibited

Who this might be right for
Knee OsteoarthritisSyndromeTraditional Chinese Medicine
Dongzhimen Hospital, Beijing 340
Early research (Phase 1)Study completedNCT05028556
What this trial is testing

A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors

Who this might be right for
Metastatic or Locally Advanced Solid Tumors
Wuhan YZY Biopharma Co., Ltd. 50
Not applicableStudy completedNCT07029035
What this trial is testing

Evaluation of Repeated Injectable PRF Following SRP in Patients With Periodontitis

Who this might be right for
Periodontitis Stage III
Saglik Bilimleri Universitesi 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05425576
What this trial is testing

OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition

Who this might be right for
Malignant Pleural Mesothelioma
Oncotelic Inc. 63
Early research (Phase 1)UnknownNCT05537051
What this trial is testing

PM1021 (Anti-TIGIT) With or Without PM8001 (Anti-PD-L1/TGF-β) in Patients With Advanced Solid Tumours

Who this might be right for
Advanced Solid Tumours
Biotheus Inc. 30
Large-scale testing (Phase 3)WithdrawnNCT01361087
What this trial is testing

Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome

Who this might be right for
Marfan Syndrome
Ann & Robert H Lurie Children's Hospital of Chicago
Not applicableLooking for participantsNCT04481256
What this trial is testing

TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY

Who this might be right for
Carcinoma, Squamous CellOesophageal Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 49
Testing effectiveness (Phase 2)Ended earlyNCT04428047
What this trial is testing

Evaluation of Bintrafusp Alfa in Operable and Untreated Head and Neck Squamous Cell Carcinoma

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
UNICANCER 7
Testing effectiveness (Phase 2)WithdrawnNCT04064190
What this trial is testing

Vactosertib with Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibition

Who this might be right for
Urothelial Carcinoma RecurrentAdvanced Urothelial Carcinoma
MedPacto, Inc.
Not applicableStudy completedNCT06604390
What this trial is testing

THE EFFECTS OF GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION ON COGNITIVE FUNCTION, EXPRESSION OF APP, MAPT, BDNF, IL-10, TGF-Β GENES, AND PLASMA MDA LEVELS IN THE ELDERLY.

Who this might be right for
Elderly Individuals Aged 60 Years or OlderMild Cognitive Impairment (MCI)
Rahmi Novita Yusuf 64
Testing effectiveness (Phase 2)UnknownNCT05785728
What this trial is testing

DB-1202 Monotherapy in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
DualityBio Inc. 150
Not applicableStudy completedNCT07048470
What this trial is testing

Efficacy of Synbiotic Supplementation on IL-10, TGF-B and Disease Activity in Systemic Lupus Erythematosus Patients

Who this might be right for
Systemic Lupus Erythematosus
Universitas Sriwijaya 36
Not applicableLooking for participantsNCT04998227
What this trial is testing

Latent TGF-β-binding Proteins Affect the Fibrotic Process in Renal Impairment and Cardiac Dysfunction

Who this might be right for
Acute Coronary SyndromeAcute Coronary Syndrome With Renal Dysfunction
National Taiwan University Hospital 300
Testing effectiveness (Phase 2)Looking for participantsNCT06543056
What this trial is testing

ES014 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT02452008
What this trial is testing

Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

Who this might be right for
Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 60
Early research (Phase 1)Ended earlyNCT04729725
What this trial is testing

SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
M.D. Anderson Cancer Center 3
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