Post-approval studies (Phase 4)UnknownNCT05705843What this trial is testingIO vs IV Vancomycin in Tourniquetless TKAWho this might be right forInfection, Surgical Site The Methodist Hospital Research Institute 40
Not applicableUnknownNCT02856971What this trial is testingKnee Hinge Prosthesis Following TKA InfectionWho this might be right forTKA Infection Hospices Civils de Lyon 49
Not applicableTemporarily pausedNCT01493375What this trial is testingSurgical Field Bacterial Contamination in Primary Total Hip (THA) and Knee (TKA) ArthroplastyWho this might be right forProsthetic Infections Northern Orthopaedic Division, Denmark 60
Not applicableStudy completedNCT02266407What this trial is testingSurgical / Economic Effect of the Aquamantys System in Blood Management for Aseptic and Septic Revision TKAWho this might be right forInfection of Total Knee Joint ProsthesisAseptic Loosening of Prosthetic Joint Medtronic Surgical Technologies 80
Early research (Phase 1)Study completedNCT04294862What this trial is testingTissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee ArthroplastyWho this might be right forProsthetic Joint Infection TenNor Therapeutics Limited 13
Not applicableStudy completedNCT00192686What this trial is testingCultures a.m.Kamme-Lindbergh in Suspicion of Infected TKAWho this might be right forTotal Knee ArthritisViral; Infection, Slow Virus Northern Orthopaedic Division, Denmark
Not applicableStudy completedNCT06661473What this trial is testingInterventional Study Exploring the Occurrence of Surgical Site Infections.Who this might be right forTotal Knee ArthroplastyTotal Hip Arthroplasty RevisionTotal Knee Arthroplasty Revision Molnlycke Health Care AB 104
Not applicableStudy completedNCT02516280What this trial is testingEffects of Gaseous Cryotherapy on Knee ROM After TKA: A Feasibility StudyWho this might be right forOsteoarthritis, Knee Centre Hospitalier de Verdun 65
Large-scale testing (Phase 3)Looking for participantsNCT07214311What this trial is testingEvaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee ArthroplastyWho this might be right forProsthetic-joint Infection Peptilogics 240
Early research (Phase 1)Study completedNCT05137314What this trial is testingStudy in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)Who this might be right forJoint Infection Peptilogics 14
Not applicableUnknownNCT05367726What this trial is testingThe Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 CasesWho this might be right forKnee Joint Prosthesis InfectionFlap NecrosisSkin Graft Complications Hospices Civils de Lyon 52
Testing effectiveness (Phase 2)Looking for participantsNCT06889701What this trial is testingEvaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI ParticipantsWho this might be right forPeriprosthetic Joint Infection (PJI) TenNor Therapeutics Inc. 33
Testing effectiveness (Phase 2)UnknownNCT02118558What this trial is testingNegative Pressure Wound Therapy -PREVENA in Prevention of Infections After Total Knee Arthroplasty (TKA)Who this might be right forTotal Knee Replacement Hadassah Medical Organization
Not applicableUnknownNCT03312088What this trial is testingMaxx Orthopedics' PCK Revision TKA Study of Component SurvivorshipWho this might be right forAseptic LooseningInfectionBone Loss+2 more Maxx Orthopedics Inc 300
Not applicableEnded earlyNCT05156762What this trial is testingTotal Joint Arthroplasty (TJA) Weight Loss StudyWho this might be right forOsteoarthritis, HipOsteoarthritis, KneeObesity, Morbid Boston Medical Center 3
Early research (Phase 1)Looking for participantsNCT07324954What this trial is testingMethylene Blue in Total Knee Arthroplasty (TKA)Who this might be right forTotal Knee ArthroplastyProsthetic-joint InfectionIrrigation University of Miami 20
Not applicableStudy completedNCT05117671What this trial is testingIs the EBJIS Definition of Prosthetic Joint Infection Meaningful in Our Clinical Practice?Who this might be right forPeriprosthetic Joint Infection (PJI) University Hospital, Basel, Switzerland 1,554
Not applicableLooking for participantsNCT05461651What this trial is testingInfection Prevention After TKA With or Without VancomycinWho this might be right forInfection Centre of Postgraduate Medical Education 1,800