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Results for “TP53”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)UnknownNCT03544723
What this trial is testing

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

Who this might be right for
Solid TumorLymphoma
MultiVir, Inc. 40
Testing effectiveness (Phase 2)UnknownNCT03381781
What this trial is testing

Decitabine,Cytarabine and Arsenic Trioxide for Acute Myeloid Leukemia With p53 Mutations

Who this might be right for
Acute Myeloid LeukemiaP53 Mutation
Li Junmin 100
Large-scale testing (Phase 3)UnknownNCT04123392
What this trial is testing

Decitabine + BUCY vs BUCY Conditioning Regimen for TP53+ Myeloid Tumors Undergoing Allo-HSCT

Who this might be right for
TP53Myeloid TumorsConditioning+1 more
Nanfang Hospital, Southern Medical University 196
Early research (Phase 1)Ended earlyNCT00410865
What this trial is testing

Wild Type p53 Adenovirus for Oral Premalignancies

Who this might be right for
Mouth Cancer
M.D. Anderson Cancer Center 4
Early research (Phase 1)Looking for participantsNCT06778863
What this trial is testing

CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorMetastatic Solid Tumor+8 more
Clasp Therapeutics, Inc. 90
Not applicableStudy completedNCT02171286
What this trial is testing

The Oncopanel Pilot (TOP) Study

Who this might be right for
Colorectal Cancer MetastaticAdvanced Non-Small Cell Lung CarcinomaAdvanced Melanoma+2 more
British Columbia Cancer Agency 432
Testing effectiveness (Phase 2)Active Not RecruitingNCT03611868
What this trial is testing

APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Who this might be right for
Unresectable or Metastatic Melanoma or Advanced Solid TumorsMelanomaUveal Melanoma+5 more
Ascentage Pharma Group Inc. 230
Large-scale testing (Phase 3)Active Not RecruitingNCT02066220
What this trial is testing

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Who this might be right for
Brain Tumors
Universitätsklinikum Hamburg-Eppendorf 360
Testing effectiveness (Phase 2)Ended earlyNCT02449655
What this trial is testing

Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53/MET) Gastric Adenocarcinoma Patients as Second-line Chemotherapy

Who this might be right for
Advanced Gastric Adenocarcinoma
Samsung Medical Center 27
Not applicableStudy completedNCT02289326
What this trial is testing

Biomarker Monitoring in TP53 Mutation Carriers

Who this might be right for
Li-Fraumeni SyndromeHereditary Cancer SyndromesTP53 Gene Germline Mutation Carrier
Scripps Health 6
Not applicableNot Yet RecruitingNCT07632170
What this trial is testing

The Efficacy and Safety of Selinisole Combined With Azacitidine and Venetoclax in the Treatment of Newly Diagnosed High-risk Myeloid Tumors With TP53 Mutations

Who this might be right for
Myeloid Tumors
Bing Han 30
Large-scale testing (Phase 3)Looking for participantsNCT06043973
What this trial is testing

Almonertinib Combined With Anlotinib as First-line Treatment for Advanced Non-small Cell Lung Cance

Who this might be right for
Advanced Non-small Cell Lung Cancer
Qianfoshan Hospital 98
Early research (Phase 1)Active Not RecruitingNCT03560882
What this trial is testing

A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies

Who this might be right for
Malignant DiseaseSolid TumorAcute Myeloid Leukemia+3 more
Joaquina Baranda 50
Testing effectiveness (Phase 2)Study completedNCT01914900
What this trial is testing

Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Who this might be right for
Locally Advanced Resectable Oral Cavity Squamous Cell Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 14
Early research (Phase 1)Study completedNCT01981525
What this trial is testing

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Who this might be right for
Li-Fraumeni Syndrome
National Cancer Institute (NCI) 26
Early research (Phase 1)Looking for participantsNCT06795009
What this trial is testing

Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

Who this might be right for
Uterine CancerEndometrial Cancer
Washington University School of Medicine 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT05491811
What this trial is testing

Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation

Who this might be right for
Non-Small Cell Lung Cancer
Sun Yat-sen University 47
Large-scale testing (Phase 3)Not Yet RecruitingNCT05489848
What this trial is testing

Chemotherapy vs Chemoradiotherapy for Post-operative Endometrial Cancer Patients With P53-mutation

Who this might be right for
Endometrial Cancer
Fudan University 294
Not applicableUnknownNCT03927599
What this trial is testing

Advanced Refractory Solid Tumors With TP53 Mutations Register Study

Who this might be right for
Solid Tumor, Adult
Tianjin Medical University Second Hospital 100
Large-scale testing (Phase 3)Looking for participantsNCT07342478
What this trial is testing

ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

Who this might be right for
CLL / SLLCLL (Chronic Lymphocytic Leukemia)CLL, Refractory+5 more
Newave Pharmaceutical Inc 306
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