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Results for “TP53 Gene Mutation”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03611868
What this trial is testing

APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Who this might be right for
Unresectable or Metastatic Melanoma or Advanced Solid TumorsMelanomaUveal Melanoma+5 more
Ascentage Pharma Group Inc. 230
Large-scale testing (Phase 3)Active Not RecruitingNCT02066220
What this trial is testing

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Who this might be right for
Brain Tumors
Universitätsklinikum Hamburg-Eppendorf 360
Testing effectiveness (Phase 2)Ended earlyNCT02449655
What this trial is testing

Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53/MET) Gastric Adenocarcinoma Patients as Second-line Chemotherapy

Who this might be right for
Advanced Gastric Adenocarcinoma
Samsung Medical Center 27
Not applicableStudy completedNCT02289326
What this trial is testing

Biomarker Monitoring in TP53 Mutation Carriers

Who this might be right for
Li-Fraumeni SyndromeHereditary Cancer SyndromesTP53 Gene Germline Mutation Carrier
Scripps Health 6
Not applicableNot Yet RecruitingNCT07632170
What this trial is testing

The Efficacy and Safety of Selinisole Combined With Azacitidine and Venetoclax in the Treatment of Newly Diagnosed High-risk Myeloid Tumors With TP53 Mutations

Who this might be right for
Myeloid Tumors
Bing Han 30
Large-scale testing (Phase 3)Looking for participantsNCT06043973
What this trial is testing

Almonertinib Combined With Anlotinib as First-line Treatment for Advanced Non-small Cell Lung Cance

Who this might be right for
Advanced Non-small Cell Lung Cancer
Qianfoshan Hospital 98
Testing effectiveness (Phase 2)Study completedNCT01914900
What this trial is testing

Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Who this might be right for
Locally Advanced Resectable Oral Cavity Squamous Cell Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 14
Early research (Phase 1)Study completedNCT01981525
What this trial is testing

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Who this might be right for
Li-Fraumeni Syndrome
National Cancer Institute (NCI) 26
Early research (Phase 1)Looking for participantsNCT06795009
What this trial is testing

Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

Who this might be right for
Uterine CancerEndometrial Cancer
Washington University School of Medicine 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT05491811
What this trial is testing

Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation

Who this might be right for
Non-Small Cell Lung Cancer
Sun Yat-sen University 47
Large-scale testing (Phase 3)Not Yet RecruitingNCT05489848
What this trial is testing

Chemotherapy vs Chemoradiotherapy for Post-operative Endometrial Cancer Patients With P53-mutation

Who this might be right for
Endometrial Cancer
Fudan University 294
Not applicableUnknownNCT03927599
What this trial is testing

Advanced Refractory Solid Tumors With TP53 Mutations Register Study

Who this might be right for
Solid Tumor, Adult
Tianjin Medical University Second Hospital 100
Large-scale testing (Phase 3)Looking for participantsNCT07342478
What this trial is testing

ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

Who this might be right for
CLL / SLLCLL (Chronic Lymphocytic Leukemia)CLL, Refractory+5 more
Newave Pharmaceutical Inc 306
Testing effectiveness (Phase 2)Looking for participantsNCT07008638
What this trial is testing

Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid LeukemiaTP53
Masonic Cancer Center, University of Minnesota 32
Early research (Phase 1)Ended earlyNCT03940352
What this trial is testing

HDM201 in Combination With MBG453 or Venetoclax in Patients With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia (AML)High-risk Myelodysplastic Syndrome (MDS)
Novartis Pharmaceuticals 52
Testing effectiveness (Phase 2)Looking for participantsNCT06130579
What this trial is testing

Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT

Who this might be right for
Myeloid LeukemiaMyelodysplastic Syndromes
Peking University People's Hospital 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT03641313
What this trial is testing

Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+5 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)UnknownNCT05932264
What this trial is testing

Apatinib and Fluzoparib With or Without Adebrelimab in Previously-treated TP53-mutant Advanced Non-small Cell Lung Cancer

Who this might be right for
NSCLCNon-small Cell Lung Cancer
Sun Yat-sen University 60
Not applicableUnknownNCT02140723
What this trial is testing

P53 and Response to Preoperative Radiotherapy for T2 and T3

Who this might be right for
Rectal Cancer
Medical University of Vienna 60
Testing effectiveness (Phase 2)Looking for participantsNCT06386146
What this trial is testing

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

Who this might be right for
Solid Tumors
Jacobio Pharmaceuticals Co., Ltd. 144
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