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Results for “TSC”

148 trials

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Showing 20 of 148 results

Early research (Phase 1)Study completedNCT01031901
What this trial is testing

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Who this might be right for
Tuberous SclerosisNeurofibromatosesAngiofibroma+1 more
The University of Texas Health Science Center, Houston 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT06392009
What this trial is testing

Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Who this might be right for
Tuberous Sclerosis ComplexFocal Cortical Dysplasia
GRIN Therapeutics, Inc. 30
Not applicableStudy completedNCT05286632
What this trial is testing

KidneYou - Innovative Digital Therapy

Who this might be right for
Chronic Kidney DiseasesDiabetesArterial Hypertension+10 more
Advice Pharma Group srl 210
Large-scale testing (Phase 3)UnknownNCT04987463
What this trial is testing

Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants

Who this might be right for
Tuberous Sclerosis Complex
Katarzyna Kotulska 60
Testing effectiveness (Phase 2)Study completedNCT00879658
What this trial is testing

Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis

Who this might be right for
Relapsing-remitting Multiple Sclerosis
Novartis Pharmaceuticals 297
Testing effectiveness (Phase 2)Looking for participantsNCT05359653
What this trial is testing

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

Who this might be right for
Multiple Sclerosis (MS)Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+4 more
University of California, San Francisco 74
Not applicableEnded earlyNCT01092208
What this trial is testing

Studies of Autistic Patients: Gene Networks and Clinical Subtypes

Who this might be right for
AutismTuberous Sclerosis
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 11
Not applicableUnknownNCT03326765
What this trial is testing

Characterizing Sleep Disorders in Children and Adults With Tuberous Sclerosis Complex (TSC)

Who this might be right for
Sleep Disorder
Universitair Ziekenhuis Brussel 60
Testing effectiveness (Phase 2)UnknownNCT01954693
What this trial is testing

Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis

Who this might be right for
Tuberous Sclerosis
Cardiff University 48
Not applicableLooking for participantsNCT06405997
What this trial is testing

The Genotype and Phenotype of Lymphangioleiomyomatosis

Who this might be right for
Sporadic LymphangioleiomyomatosisTSC-associated Lymphangioleiomyomatosis
National Taiwan University Hospital 100
Testing effectiveness (Phase 2)Ended earlyNCT03363763
What this trial is testing

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Who this might be right for
Angiofibroma of FaceTuberous Sclerosis
Aucta Pharmaceuticals, Inc 24
Large-scale testing (Phase 3)Study completedNCT02544750
What this trial is testing

An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

Who this might be right for
Tuberous Sclerosis ComplexSeizures
Jazz Pharmaceuticals 199
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Early research (Phase 1)Study completedNCT04808622
What this trial is testing

Safety and Efficacy of Trans Sodium Crocetinate (TSC) in Enhancing Tissue Oxygen Levels in Healthy Volunteers

Who this might be right for
Healthy Subjects
Diffusion Pharmaceuticals Inc 30
Post-approval studies (Phase 4)Active Not RecruitingNCT05864846
What this trial is testing

Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex

Who this might be right for
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
Jazz Pharmaceuticals 79
Large-scale testing (Phase 3)Study completedNCT01906866
What this trial is testing

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

Who this might be right for
Sleep Disorders
Neurim Pharmaceuticals Ltd. 125
Testing effectiveness (Phase 2)Study completedNCT04573322
What this trial is testing

Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects

Who this might be right for
SARS-CoV-2 (Covid19)
Diffusion Pharmaceuticals Inc 25
Post-approval studies (Phase 4)Study completedNCT00989742
What this trial is testing

Doxycycline In Lymphangioleiomyomatosis (LAM)

Who this might be right for
LymphangioleiomyomatosisTuberous Sclerosis
University of Nottingham 24
Not applicableEnrolling By InvitationNCT06879665
What this trial is testing

TANDem-2: Closing the Gap to Interventions for TAND

Who this might be right for
Adult Caregivers of Individuals With TSCTuberous Sclerosis Complex (TSC)
Vrije Universiteit Brussel 30
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