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Results for “TSC”

148 trials

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Showing 20 of 148 results

Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Testing effectiveness (Phase 2)WithdrawnNCT03166176
What this trial is testing

Phase II Trial of Vistusertib（AZD2014） Single Agent in TSC1or 2 Null or TSC 1/2 Mutation Solid Cancer Patients Refractory to Standard Chemotherapy

Who this might be right for
Solid Tumor
Samsung Medical Center
Early research (Phase 1)Study completedNCT01031901
What this trial is testing

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Who this might be right for
Tuberous SclerosisNeurofibromatosesAngiofibroma+1 more
The University of Texas Health Science Center, Houston 52
Large-scale testing (Phase 3)Active Not RecruitingNCT02962414
What this trial is testing

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Who this might be right for
Tuberous Sclerosis Complex
Novartis Pharmaceuticals 206
Post-approval studies (Phase 4)Study completedNCT02563041
What this trial is testing

Comparative Effectiveness of 30%TSC and Heparin Lock Solution in Hemodialysis Catheters

Who this might be right for
Catheter Related Infection
Catholic University of Pelotas 179
Large-scale testing (Phase 3)Study completedNCT00790400
What this trial is testing

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

Who this might be right for
Tuberous Sclerosis Complex (TSC)Lymphangioleiomyomatosis (LAM)
Novartis Pharmaceuticals 118
Testing effectiveness (Phase 2)UnknownNCT00490789
What this trial is testing

Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM

Who this might be right for
Tuberous SclerosisLymphangioleiomyomatosis
Cardiff University 14
Post-approval studies (Phase 4)Study completedNCT02338609
What this trial is testing

Long-term Monitoring of Growth and Development of Pediatric Patients Previously Treated With Everolimus

Who this might be right for
Growth and Development
Novartis Pharmaceuticals 15
Testing effectiveness (Phase 2)Study completedNCT05364021
What this trial is testing

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome
Longboard Pharmaceuticals 52
Testing effectiveness (Phase 2)Study completedNCT01929642
What this trial is testing

Rapalogues for Autism Phenotype in TSC: A Feasibility Study

Who this might be right for
Tuberous Sclerosis ComplexSelf-injuryAutism
Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3
Post-approval studies (Phase 4)Active Not RecruitingNCT05252585
What this trial is testing

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

Who this might be right for
Renal Angiomyolipoma
Novartis Pharmaceuticals 4
Not applicableActive Not RecruitingNCT02461459
What this trial is testing

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

Who this might be right for
Tuberous SclerosisAutism DisorderIntellectual Disability
Boston Children's Hospital 205
Post-approval studies (Phase 4)Ended earlyNCT01266291
What this trial is testing

Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients

Who this might be right for
Complex Partial Seizures
University of Pennsylvania 1
Testing effectiveness (Phase 2)Study completedNCT04285346
What this trial is testing

Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)

Who this might be right for
Tuberous Sclerosis
Marinus Pharmaceuticals 23
Testing effectiveness (Phase 2)Study completedNCT02451696
What this trial is testing

A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD

Who this might be right for
EpilepsyTuberous Sclerosis ComplexFocal Cortical Dysplasia
NYU Langone Health 15
Large-scale testing (Phase 3)Ended earlyNCT03393000
What this trial is testing

Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects

Who this might be right for
Glioblastoma
Diffusion Pharmaceuticals Inc 19
Early research (Phase 1)Ended earlyNCT00826930
What this trial is testing

Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma

Who this might be right for
High Grade Glioma
Diffusion Pharmaceuticals Inc 1
Large-scale testing (Phase 3)Ended earlyNCT04485104
What this trial is testing

Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Who this might be right for
Seizure in Participants With Tuberous Sclerosis ComplexSeizure in Participants With Dravet SyndromeSeizure in Participants With Lennox-Gastaut Syndrome
Jazz Pharmaceuticals 3
Large-scale testing (Phase 3)Study completedNCT02635789
What this trial is testing

Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)

Who this might be right for
Tuberous SclerosisAngiofibromaHypomelanotic Macule+1 more
Nobelpharma 62
Not applicableEnded earlyNCT01092208
What this trial is testing

Studies of Autistic Patients: Gene Networks and Clinical Subtypes

Who this might be right for
AutismTuberous Sclerosis
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 11
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