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Results for “Therapy, Gene”

1,897 trials

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Showing 20 of 1,897 results

Testing effectiveness (Phase 2)Looking for participantsNCT06383533
What this trial is testing

Disitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct Adenocarcinoma

Who this might be right for
Bile Duct Adenocarcinoma Non-ResectableHER2 Gene Mutation
Zhejiang Cancer Hospital 28
Early research (Phase 1)Study completedNCT00569985
What this trial is testing

Gene Therapy-Treated Stem Cells in Treating Patients Undergoing Stem Cell Transplant for Intermediate-Grade or High-Grade AIDS-Related Lymphoma

Who this might be right for
Lymphoma
City of Hope Medical Center 5
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Early research (Phase 1)Study completedNCT01517464
What this trial is testing

A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors

Who this might be right for
Neoplasm
SynerGene Therapeutics, Inc. 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07173933
What this trial is testing

Phase I/II Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of GC310 Injection in Patients With Wilson's Disease (WD)

Who this might be right for
Wilson Disease
GeneCradle Inc 15
Not applicableWithdrawnNCT02006849
What this trial is testing

ACTH Treatment of APOL1- Associated Nephropathy

Who this might be right for
Kidney Disease
Wake Forest University Health Sciences
Not applicableWithdrawnNCT06634836
What this trial is testing

Patient Interview Study to Explore the Impact of Gene Therapy in Hemophilia A & B

Who this might be right for
Hemophilia AHemophilia B
Pfizer
Early research (Phase 1)WithdrawnNCT00429078
What this trial is testing

Trial of 2nd Generation Anti-CEA Designer T Cells in Gastric Cancer

Who this might be right for
Gastric Cancer
Roger Williams Medical Center
Early research (Phase 1)Study completedNCT00494195
What this trial is testing

Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)

Who this might be right for
Muscular Dystrophies
Nationwide Children's Hospital 6
Not applicableStudy completedNCT01349387
What this trial is testing

Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing

Who this might be right for
Type 2 Diabetes
Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 25
Not applicableActive Not RecruitingNCT07303647
What this trial is testing

Genes Associated With Bone Metabolism in the Saliva During Orthodontic Treatment

Who this might be right for
Gene Expression ProfilingOrthodentic Appliances
Kurdistan Higher Council of Medical Specialties 24
Early research (Phase 1)Looking for participantsNCT07198555
What this trial is testing

A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of BBM-A101 in the Treatment of Knee Osteoarthritis.

Who this might be right for
Knee Osteoarthritis
Belief BioMed (Beijing) Co., Ltd 81
Testing effectiveness (Phase 2)Looking for participantsNCT06323525
What this trial is testing

TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma

Who this might be right for
Non-hodgkin Lymphoma
Chinese PLA General Hospital 30
Post-approval studies (Phase 4)UnknownNCT05247476
What this trial is testing

Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Cancer Patients.

Who this might be right for
Thyroid Cancer, PapillaryHypothyroidism
Zhongshan Hospital Xiamen University 50
Early research (Phase 1)Study completedNCT00004038
What this trial is testing

Gene Therapy Plus Chemotherapy in Treating Patients With Breast Cancer

Who this might be right for
Breast Cancer
National Cancer Institute (NCI) 20
Early research (Phase 1)Active Not RecruitingNCT06825858
What this trial is testing

A Phase I, Open-label, Multicenter, Dose-Escalating Study to Evaluate the Safety and Tolerability of KH658 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration

Who this might be right for
Age-Related Macular Degeneration
Chengdu Origen Biotechnology Co., Ltd. 9
Large-scale testing (Phase 3)Study completedNCT02965378
What this trial is testing

Lung-MAP: AZD4547 as Second-Line Therapy in Treating FGFR Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
FGFR1 Gene AmplificationFGFR1 Gene MutationFGFR2 Gene Amplification+5 more
SWOG Cancer Research Network 43
Large-scale testing (Phase 3)Looking for participantsNCT07236606
What this trial is testing

RGX-121-3102 Gene Therapy in Participants With MPS II (Hunter Syndrome)

Who this might be right for
MPS IIHunter Syndrome (MPS II)
REGENXBIO Inc. 2
Not applicableLooking for participantsNCT06887348
What this trial is testing

Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

Who this might be right for
MelanomaMetastatic MelanomaAdvanced Solid Tumor+1 more
Replimune Inc. 50
Testing effectiveness (Phase 2)Ended earlyNCT00451035
What this trial is testing

Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic Phase

Who this might be right for
Chronic Myeloid Leukemia in Chronic Phase
Novartis Pharmaceuticals 29
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