Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Therapy, Gene”

1,997 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 1,997 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05407636
What this trial is testing

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

Who this might be right for
AMDnAMDWet Age-related Macular Degeneration+3 more
AbbVie 735
Testing effectiveness (Phase 2)Active Not RecruitingNCT03326336
What this trial is testing

Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa

Who this might be right for
Non-syndromic Retinitis Pigmentosa
GenSight Biologics 10
Not applicableUnknownNCT03979911
What this trial is testing

Evaluation of Pertuzumab-Trastuzumab and Taxane in the Standard Treatment of Metastatic Breast Cancer

Who this might be right for
Breast NeoplasmsHER-2 Gene Amplification
University Hospital, Brest 63
Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Not applicableStudy completedNCT01416467
What this trial is testing

Characterization of the Patient Population With Galactosialidosis

Who this might be right for
Galactosialidosis
St. Jude Children's Research Hospital 3
Not applicableUnknownNCT04249674
What this trial is testing

Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol

Who this might be right for
InteractionPain
University Hospital, Geneva 172
Early research (Phase 1)Looking for participantsNCT06885697
What this trial is testing

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Who this might be right for
MesotheliomaNeoplasmsStomach Neoplasms+5 more
National Cancer Institute (NCI) 100
Testing effectiveness (Phase 2)UnknownNCT02481310
What this trial is testing

Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma

Who this might be right for
Adult Burkitt LymphomaB-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt LymphomaDiffuse Large B-Cell Lymphoma+2 more
Northwestern University 38
Testing effectiveness (Phase 2)Ended earlyNCT06716853
What this trial is testing

A Clinical Gene Therapy Study With Hematopoietic Stem Cells for the Treatment, With Single Dose of Temferon, of Patients Suffering From Metastatic Renal Cell Carcinoma

Who this might be right for
Clear Cell RCC
Genenta Science 10
Testing effectiveness (Phase 2)Ended earlyNCT05689021
What this trial is testing

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

Who this might be right for
Castration-Resistant Prostate CarcinomaMetastatic Prostate AdenocarcinomaStage IVB Prostate Cancer AJCC v8
Mayo Clinic 8
Large-scale testing (Phase 3)Active Not RecruitingNCT05606614
What this trial is testing

A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)

Who this might be right for
Rett Syndrome
Taysha Gene Therapies, Inc. 17
Not applicableStudy completedNCT01199393
What this trial is testing

Genetic Polymorphisms Predict Chemotherapeutic Outcomes in Patients With Metastatic Breast Cancer

Who this might be right for
Breast NeoplasmDrug TherapyPolymorphism,Single Nucleotide
Peking University Cancer Hospital & Institute 153
Early research (Phase 1)Study completedNCT00403221
What this trial is testing

Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer

Who this might be right for
Prostatic Neoplasms
Baylor College of Medicine 19
Not applicableStudy completedNCT03727477
What this trial is testing

Efficacy of Treatment Sequences in Patients With Non-small Cell Lung Cancer Receiving Lorlatinib

Who this might be right for
Non-small Cell Lung Cancer MetastaticALK Gene Rearrangement PositiveROS-1 Gene Rearrangement Positive
Intergroupe Francophone de Cancerologie Thoracique 291
Early research (Phase 1)Ended earlyNCT02112162
What this trial is testing

Gene Expression and FDG PET/MRI in Evaluating Treatment Response in Patients With Locally Advanced Rectal Cancer Undergoing Chemotherapy and Radiation Therapy Before Surgery

Who this might be right for
Rectal Neoplasms
Washington University School of Medicine 2
Early research (Phase 1)Study completedNCT00003588
What this trial is testing

Gene Therapy in Treating Patients With Ovarian Cancer

Who this might be right for
Ovarian Cancer
National Cancer Institute (NCI) 30
Post-approval studies (Phase 4)UnknownNCT02973646
What this trial is testing

Peginterferon Alfa-2b Treatment in HBeAg(+) Chronic Hepatitis b Patients Based on Interferon Gene Mutation and Receptor Detection

Who this might be right for
Chronic Hepatitis b
Third Affiliated Hospital, Sun Yat-Sen University 100
Large-scale testing (Phase 3)WithdrawnNCT06297486
What this trial is testing

Study of a Gene Therapy Treatment for Hemophilia A

Who this might be right for
Hemophilia A
Spark Therapeutics, Inc.
Early research (Phase 1)Ended earlyNCT01886573
What this trial is testing

Azacitidine and Entinostat in Treating Patients With Newly Diagnosed Stage IA-IIIA Non-Small Lung Cancer Undergoing Surgery

Who this might be right for
Stage IA Non-Small Cell Lung CarcinomaStage IB Non-Small Cell Lung CarcinomaStage IIA Non-Small Cell Lung Carcinoma+2 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Looking for participantsNCT05824169
What this trial is testing

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 1 Patients

Who this might be right for
Spinal Muscular Atrophy
GeneCradle Inc 18
Next Page