Post-approval studies (Phase 4)Study completedNCT01680549What this trial is testingPain Control With Total Knee ReplacementWho this might be right forPostoperative Pain Texas Tech University Health Sciences Center 50
Not applicableLooking for participantsNCT07561333What this trial is testingComparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee ArthroplastyWho this might be right forPostoperative PainTotal Knee Arthroplasty Hitit University 78
Not applicableStudy completedNCT01307202What this trial is testingMorphine Consumption in Joint Replacement Patients, With or Without Gabapentin TreatmentWho this might be right forPost Operative PainTotal Knee Replacement McMaster University 101
Not applicableLooking for participantsNCT05920382What this trial is testingRadiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.Who this might be right forChronic Post-surgical PainChronic Post Operative PainChronic Knee Pain Consorci Sanitari de l'Alt Penedès i Garraf 86
Not applicableStudy completedNCT06460350What this trial is testingNEUROCUPLE™ in TKA Patients to Enhance Pain ManagementWho this might be right forTotal Knee Arthroplasty nCap Medical 156
Post-approval studies (Phase 4)Not Yet RecruitingNCT04432259What this trial is testingOral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee ArthroplastyWho this might be right forArthritis KneePostoperative NauseaPostoperative Pain Henry Ford Health System 300
Not applicableStudy completedNCT05943080What this trial is testingComparison of IPACK Block and PCI for Postoperative Analgesia and Function Recovery Following Total Knee ArthroplastyWho this might be right forTotal Knee ArthroplastyKnee Pain, Functionality Kirsehir Ahi Evran Universitesi 195
Post-approval studies (Phase 4)WithdrawnNCT02624856What this trial is testingLiposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee ArthroplastyWho this might be right forOsteoarthritisPain, Postoperative Albany Medical College
Very early researchStudy completedNCT02115945What this trial is testingFemoral and Epidural Block After Total Knee ArthroplastyWho this might be right forAcute Postoperative PainChronic Postoperative Pain Aydin Adnan Menderes University 40
Not applicableStudy completedNCT06436105What this trial is testingComparison of Fasia Iliac Compartment Block and 4in1 BlockWho this might be right forPain, Postoperative Diskapi Yildirim Beyazit Education and Research Hospital 60
Not applicableStudy completedNCT07744503What this trial is testingComparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee ReplacementWho this might be right forPain, PostoperativeOsteoarthritis, KneeArthroplasty, Replacement, Knee Christopher Male 78
Not applicableStudy completedNCT02468934What this trial is testingElectrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty (TKA) Using the SPRINT SystemWho this might be right forTotal Knee ReplacementTotal Knee ArthroplastyPain+2 more SPR Therapeutics, Inc. 24
Large-scale testing (Phase 3)Looking for participantsNCT06740214What this trial is testingAnalgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee ArthroplastyWho this might be right forPain, PostoperativeAnalgesic EffectTotal Knee Arthroplasty+2 more The University of Hong Kong 177
Testing effectiveness (Phase 2)UnknownNCT05561309What this trial is testingPhase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain ManagementWho this might be right forTotal Knee Arthroplasty Shanghai Hengrui Pharmaceutical Co., Ltd. 89
Not applicableStudy completedNCT06179628What this trial is testingLow vs Standard Local Anesthetics Boluses for Continuous Adductor Canal Block in Total Knee ArthroplastyWho this might be right forKnee Arthropathy Chulalongkorn University 140
Post-approval studies (Phase 4)Study completedNCT05924412What this trial is testingParecoxib in Total Knee ArthroplastyWho this might be right forPain, PostoperativePain, AcuteAnalgesia+3 more University of Chile 40
Not applicableUnknownNCT06339151What this trial is testingComparing Single Dose and Multiple Dose of Dexamethasone Post TKAWho this might be right forOsteo Arthritis KneePain, Postoperative Thammasat University Hospital 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07330765What this trial is testingAnalgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee ArthroplastyWho this might be right forTotal Knee Replacement Abdelrahman Gaber Sayed Elkhateeb 1
Not applicableLooking for participantsNCT07080892What this trial is testingThe Effect of Distal Versus Proximal iPACK on Pain After Total Knee ArthroplastyWho this might be right forPostoperative Pain Following Knee Arthroplasty Comenius University 120
Post-approval studies (Phase 4)WithdrawnNCT01511211What this trial is testingDuration of Leg Nerve Blocks With Dexamethasone Added to Local AnestheticWho this might be right forPainTotal Knee Arthroplasty University of New Mexico