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Results for “Total Neoadjuvant Therapy”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT07005570
What this trial is testing

Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer （SPARK）

Who this might be right for
pMMR/MSS Locally Advanced Rectal Cancer
Dechang Diao 86
Testing effectiveness (Phase 2)UnknownNCT04293419
What this trial is testing

Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Grupo Espanol Multidisciplinario del Cancer Digestivo 58
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07543848
What this trial is testing

A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer

Who this might be right for
Rectal NeoplasmsRectal Adenocarcinoma
Chongqing University Cancer Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT07018570
What this trial is testing

An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastroesophageal Junction (GEJ) Adenocarcinoma
National Cancer Center Hospital East 26
Large-scale testing (Phase 3)UnknownNCT03177382
What this trial is testing

Total Neoadjuvant Treatment vs. Chemoradiotherapy in Local Advanced Rectal Cancer With High Risk Factors

Who this might be right for
Total Neoadjuvant TreatmentChemoradiotherapyLocal Advanced Rectal Cancer+1 more
West China Hospital 458
Testing effectiveness (Phase 2)Looking for participantsNCT07347951
What this trial is testing

A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Wenzhou Medical University 30
Testing effectiveness (Phase 2)Looking for participantsNCT07292298
What this trial is testing

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

Who this might be right for
Rectal AdenocarcinomaRectal Cancer
University of Colorado, Denver 44
Testing effectiveness (Phase 2)Temporarily pausedNCT04558684
What this trial is testing

Radiotherapy With Neoadjuvant Chemotherapy and Immunotherapy in Rectal Cancer

Who this might be right for
Rectal CancerRadiotherapyImmunotherapy+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07101666
What this trial is testing

Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer

Who this might be right for
Gastric Cancer
Washington University School of Medicine 20
Not applicableEnrolling By InvitationNCT07346248
What this trial is testing

Postoperative Complications After Neoadjuvant Chemoradiotherapy or Short-course Radiotherapy and Total Neoadjuvant Treatment: a Multicentric Retrospective Cohort Study

Who this might be right for
Adult Patients With Locally Advanced Rectal Cancer Indicated to Neoadjuvant Therapy and Surgery
Istituto Clinico Humanitas 266
Not applicableStudy completedNCT01836926
What this trial is testing

TaTME Versus Open Intersphincteric Resection After Neoadjuvant Concurrent Chemoradiotherapy.

Who this might be right for
Rectal Cancer
Osama Mohammad Ali ElDamshety 110
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07527325
What this trial is testing

Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma

Who this might be right for
Melanoma (Skin)
University of California, Irvine 35
Testing effectiveness (Phase 2)UnknownNCT04340401
What this trial is testing

Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen

Who this might be right for
Rectal Cancer
Peking University Cancer Hospital & Institute 25
Large-scale testing (Phase 3)Looking for participantsNCT06028737
What this trial is testing

Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer

Who this might be right for
Gastric CancerStomach CancerGastroEsophageal Cancer+13 more
Ukrainian Society of Clinical Oncology 150
Testing effectiveness (Phase 2)Looking for participantsNCT07561060
What this trial is testing

Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy

Who this might be right for
Rectal Cancer
Fudan University 50
Not applicableLooking for participantsNCT05984576
What this trial is testing

Radiotherapy & Total Neoadjuvant Therapy for Recurrent Rectal Cancer in Previously Irradiated Patients, an Italian Association for Radiotherapy and Clinical Oncology (AIRO)-GI Platform: a Multi-centre Prospective Observational Study

Who this might be right for
Rectal Neoplasm
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 88
Early research (Phase 1)Looking for participantsNCT05412082
What this trial is testing

SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
University of Miami 25
Testing effectiveness (Phase 2)Ended earlyNCT03170115
What this trial is testing

Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaLocally Advanced Malignant NeoplasmChemoradiation
Instituto Nacional de Cancer, Brazil 25
Not applicableStudy completedNCT06668402
What this trial is testing

Study of Daily Step Count and Treatment Response in Rectal Cancer (STEP-R)

Who this might be right for
ExerciseTotal Neoadjuvant TreatmentRectal Tumors+2 more
Gazi University 160
Not applicableUnknownNCT05873621
What this trial is testing

Indocyanine Green-guided Lymphadenectomy in Laparoscopic Total Mesorectal Excision for Low Rectal Cancer After Neoadjuvant Chemoradiotherapy

Who this might be right for
Rectal CancerLymph Node Cancer Metastatic
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 60
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