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Results for “Transfusion-dependent Iron Overload”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Study completedNCT05355766
What this trial is testing

Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients

Who this might be right for
ThalassemiaIron Overload
Hangzhou Zede Pharma-Tech Co., Ltd. 16
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Testing effectiveness (Phase 2)Study completedNCT02435212
What this trial is testing

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Who this might be right for
Transfusion-dependent Anemia
Novartis Pharmaceuticals 224
Post-approval studies (Phase 4)Study completedNCT00481143
What this trial is testing

Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron Overload

Who this might be right for
Myelodysplastic SyndromesTransfusion Dependent Iron Overload
Novartis Pharmaceuticals 63
Testing effectiveness (Phase 2)Study completedNCT00390858
What this trial is testing

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Who this might be right for
Transfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)WithdrawnNCT03801889
What this trial is testing

SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias

Who this might be right for
Iron OverloadBeta-Thalassemia
Abfero Pharmaceuticals, Inc
Not applicableStudy completedNCT02090699
What this trial is testing

MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias

Who this might be right for
Thalassemia MajorChronic Blood Transfusion Related Iron Overload
University Health Network, Toronto 42
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Testing effectiveness (Phase 2)Study completedNCT01740713
What this trial is testing

Pharmacokinetic Study of Deferiprone in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 23
Large-scale testing (Phase 3)Study completedNCT00529152
What this trial is testing

Safety and Efficacy of Ferriprox™ (Deferiprone) Oral Solution in Iron Overloaded Pediatric Patients

Who this might be right for
Iron Overload
ApoPharma 100
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
Testing effectiveness (Phase 2)Looking for participantsNCT06421636
What this trial is testing

Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Who this might be right for
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals 95
Large-scale testing (Phase 3)Study completedNCT01033747
What this trial is testing

Safety and Efficacy of Deferasirox in Patients With Transfusion Dependent Iron Overload - a Non-comparative Extension Study

Who this might be right for
Liver Iron Overload
Novartis Pharmaceuticals 70
Large-scale testing (Phase 3)Study completedNCT00171821
What this trial is testing

A Study Assessing the Efficacy and Safety of Deferasirox in Patients With Transfusion-dependent Iron Overload

Who this might be right for
Transfusion-dependent Iron Overload
Novartis Pharmaceuticals 1,784
Not applicableStudy completedNCT04515680
What this trial is testing

Endocrine Function During Deferasirox Therapy

Who this might be right for
Iron OverloadTransfusion-dependent ThalassemiaEndocrine; Complications
University of Campania Luigi Vanvitelli 426
Post-approval studies (Phase 4)Study completedNCT00564941
What this trial is testing

Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload

Who this might be right for
Myelodysplastic SyndromesBeta-Thalassemia
Novartis Pharmaceuticals 309
Testing effectiveness (Phase 2)Study completedNCT00349453
What this trial is testing

Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients

Who this might be right for
Hemochromatosis
Lipomed 24
Not applicableStudy completedNCT00466063
What this trial is testing

ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With Deferasirox

Who this might be right for
Anemia
Novartis Pharmaceuticals 108
Post-approval studies (Phase 4)Ended earlyNCT01818726
What this trial is testing

Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia Patients

Who this might be right for
Aplastic Anemia
Novartis Pharmaceuticals 15
Testing effectiveness (Phase 2)Ended earlyNCT03381833
What this trial is testing

A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia

Who this might be right for
Beta-Thalassemia
La Jolla Pharmaceutical Company 84
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