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Results for “Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP)”

51 trials

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Showing 20 of 51 results

Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Not applicableUnknownNCT04986826
What this trial is testing

Exercise Effect on Transthyretin Stability

Who this might be right for
Amyloidosis TransthyretinAthlete Heart
Oregon Health and Science University 24
Not applicableWithdrawnNCT02713880
What this trial is testing

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)

Who this might be right for
Transthyretin AmyloidosisTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin Amyloid Cardiopathy
CENTOGENE GmbH Rostock
Not applicableStudy completedNCT04201418
What this trial is testing

Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Who this might be right for
Hereditary Transthyretin-mediated (ATTRv) AmyloidosisPolyneuropathy
Alnylam Pharmaceuticals 67
Large-scale testing (Phase 3)Study completedNCT01737398
What this trial is testing

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Who this might be right for
FAPFamilial Amyloid PolyneuropathyTTR+2 more
Ionis Pharmaceuticals, Inc. 173
Not applicableActive Not RecruitingNCT05873868
What this trial is testing

Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or Vutrisiran

Who this might be right for
Transthyretin AmyloidosisAmyloidosis, Hereditary
Rennes University Hospital 20
Not applicableStudy completedNCT05560555
What this trial is testing

Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv)Polyneuropathy
Pfizer 5
Not applicableUnknownNCT05699044
What this trial is testing

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation

Who this might be right for
Amyloid CardiomyopathyBlock, AV
Steen Hvitfeldt Poulsen 170
Not applicableApproved For MarketingNCT02939820
What this trial is testing

Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)

Who this might be right for
TTR-mediated AmyloidosisAmyloidosis, HereditaryAmyloid Neuropathies, Familial+3 more
Alnylam Pharmaceuticals
Not applicableEnrolling By InvitationNCT06714019
What this trial is testing

PL_GNT01_ISR_Grant 53234273

Who this might be right for
Transthyretin Cardiomyopathy (TTR-CM)Transthyretin (TTR) Amyloid CardiomyopathyTransthyretin Amyloidosis
National Institute of Cardiology, Warsaw, Poland 100
Not applicableUnknownNCT04985734
What this trial is testing

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy

Who this might be right for
Amyloidosis CardiacAmyloid PolyneuropathyAmyloidosis+3 more
University Hospital, Antwerp 200
Not applicableStudy completedNCT03190577
What this trial is testing

Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology

Who this might be right for
Familial Amyloid NeuropathyTransthyretin Amyloidosis
Nantes University Hospital 400
Not applicableActive Not RecruitingNCT04869631
What this trial is testing

Screening for Amyloidosis Before Aortic Valve Elective Replacement

Who this might be right for
AmyloidosisAortic Valve Stenosis
Charite University, Berlin, Germany 1,000
Not applicableStudy completedNCT01604122
What this trial is testing

Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers

Who this might be right for
Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP)Transthyretin Cardiomyopathy (TTR-CM)Familial Amyloid Cardiomyopathy+1 more
Pfizer 1
Large-scale testing (Phase 3)Study completedNCT01960348
What this trial is testing

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Who this might be right for
TTR-mediated AmyloidosisAmyloidosis, HereditaryAmyloid Neuropathies, Familial+3 more
Alnylam Pharmaceuticals 225
Not applicableStudy completedNCT01705626
What this trial is testing

Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP)

Who this might be right for
Polyneuropathy, AmyloidNeuropathic PainCardiac Failure+2 more
CENTOGENE GmbH Rostock 500
Not applicableLooking for participantsNCT04535349
What this trial is testing

Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR Amyloidosis

Who this might be right for
Amyloidosis Transthyretin
University Hospital, Caen 35
Testing effectiveness (Phase 2)Study completedNCT02191826
What this trial is testing

Study of SOM0226 in Familial Amyloid Polyneuropathy

Who this might be right for
Familial Amyloid Polyneuropathy (FAP)
SOM Innovation Biotech SA 17
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