Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Treatment-resistant Bipolar Depression”

76 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 76 results

Not applicableStudy completedNCT05228457
What this trial is testing

Intensive TMS for Bipolar Depression

Who this might be right for
Bipolar DepressionTreatment Resistant Depression
University of Pennsylvania 34
Testing effectiveness (Phase 2)Ended earlyNCT02882711
What this trial is testing

The UTHealth Ketamine Project

Who this might be right for
Treatment Resistant DepressionMajor Depressive DisorderBipolar Disorder
The University of Texas Health Science Center, Houston 10
Not applicableActive Not RecruitingNCT05172271
What this trial is testing

Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

Who this might be right for
Major Depressive DisorderBipolar DisorderUnipolar Major Depression
National Institute of Mental Health (NIMH) 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07644767
What this trial is testing

Adjunctive Oral KET-AD Capsules in Treatment Resistant Bipolar Depression

Who this might be right for
Treatment Resistant Bipolar Depression
Neurocentrx Pharma Pty Ltd 160
Not applicableEnded earlyNCT06431386
What this trial is testing

Behavioural Activation Therapy and Esketamine for Resistant Depression

Who this might be right for
Depressive Disorder, Treatment-ResistantDepressive Disorder, MajorBipolar Disorder
The Royal's Institute of Mental Health Research 6
Not applicableEnded earlyNCT03360942
What this trial is testing

Long Term Follow-up of Deep Brain Stimulation for Treatment-Resistant Depression

Who this might be right for
Treatment Resistant DepressionDepressive Disorder, Treatment-ResistantDepression, Bipolar
Dartmouth-Hitchcock Medical Center 5
Large-scale testing (Phase 3)Study completedNCT01586793
What this trial is testing

Repetitive Transcranial Magnetic Stimulation for Treating Resistant Bipolar Depression

Who this might be right for
Bipolar Depression
Douglas Mental Health University Institute 8
Not applicableStudy completedNCT01983904
What this trial is testing

DBS for Treatment Resistant Depression

Who this might be right for
Depressive Disorder, Treatment-Resistant
University of Calgary 22
Not applicableLooking for participantsNCT07127913
What this trial is testing

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Who this might be right for
Bipolar II DisorderBipolar II Disorder, Most Recent Episode Major Depressive
Andrew Krystal 10
Not applicableStudy completedNCT05177146
What this trial is testing

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression

Who this might be right for
Bipolar Disorder (BD)Suicidality
Centre for Addiction and Mental Health 16
Not applicableWithdrawnNCT02238730
What this trial is testing

Ultrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive Therapy

Who this might be right for
DepressionDepressive DisorderTreatment Resistant Depressive Disorder+2 more
Kaiser Permanente
Not applicableLooking for participantsNCT07741981
What this trial is testing

Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment

Who this might be right for
SchizophreniaTreatment Resistant Depression (TRD)Bipolar Disorder (BD)+2 more
Centre Hospitalier St Anne 700
Testing effectiveness (Phase 2)Looking for participantsNCT06943573
What this trial is testing

Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

Who this might be right for
Bipolar II Depression
Lakshmi N Yatham 90
Post-approval studies (Phase 4)Study completedNCT00835120
What this trial is testing

Pioglitazone for the Treatment of Bipolar Disorder and Comorbid Metabolic Syndrome or Insulin Resistance

Who this might be right for
Metabolic SyndromeBipolar DepressionInsulin Resistance
University Hospitals Cleveland Medical Center 34
Not applicableStudy completedNCT01973478
What this trial is testing

Deep Brain Stimulation in Patients With Chronic Treatment Resistant Depression

Who this might be right for
Major Depressive DisorderRecurrent Depressive DisorderBipolar Disorder
Rennes University Hospital 9
Testing effectiveness (Phase 2)Study completedNCT00034229
What this trial is testing

Clinical Trial of Felbamate for Treatment-Resistant Bipolar Depression

Who this might be right for
Bipolar Disorder
National Institute of Mental Health (NIMH) 52
Not applicableStudy completedNCT01898429
What this trial is testing

Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD)

Who this might be right for
Treatment Resistant DepressionDepressive Disorder, Treatment-ResistantDepression, Bipolar
Paul Holtzheimer 5
Large-scale testing (Phase 3)Looking for participantsNCT04569448
What this trial is testing

Brexpiprazole Treatment for Bipolar I Depression

Who this might be right for
Bipolar Depression
Douglas Mental Health University Institute 58
Early research (Phase 1)Active Not RecruitingNCT06506019
What this trial is testing

Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression

Who this might be right for
Bipolar Depression
University Health Network, Toronto 30
Not applicableStudy completedNCT01344733
What this trial is testing

A Non Interventional Study to Investigating the Ratio of Mis-diagnosed Bipolar Symptoms in Patient With Major Depressive Disorder (MDD)

Who this might be right for
Major Depressive DisorderMDD
AstraZeneca 660
Next Page