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Results for “Tumor Mutation Burden”

42 trials

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Showing 20 of 42 results

Testing effectiveness (Phase 2)Study completedNCT02311569
What this trial is testing

Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation

Who this might be right for
Myeloproliferative NeoplasmPrimary MyelofibrosisEssential Thrombocythemia+1 more
Swiss Cancer Institute 39
Not applicableLooking for participantsNCT06536257
What this trial is testing

Personalised Immunotherapy Platform

Who this might be right for
MelanomaCutaneous Squamous Cell CarcinomaBasal Cell Carcinoma+2 more
Melanoma Institute Australia 1,000
Not applicableUnknownNCT05602337
What this trial is testing

A Prospective Multicenter Sample Collection Study Using Non-invasive Methods to Investigate Mutation Burden in Non-lesional Facial Skin of Patients With a Hx of Skin Cancer

Who this might be right for
Melanoma and Other Malignant Neoplasms of Skin
DermTech 180
Not applicableLooking for participantsNCT05929365
What this trial is testing

Innovative Approach to Detect Recurrent Colorectal Lesions With Surveillance Via Mutation Analysis & Clinical Phenotype

Who this might be right for
Predictive Cancer Model
Military University Hospital, Prague 200
Not applicableUnknownNCT04191226
What this trial is testing

Genetic Mutation in Recurrent Cervical Cancer

Who this might be right for
Recurrent Cervical CancerNucleotide VariantCopy Number Variation+6 more
Lei Li 300
Not applicableLooking for participantsNCT04942080
What this trial is testing

Interest of CALR Allele Burden in Diagnosis and Follow-up of Patients With CALR Mutated Myeloproliferative Syndromes (CALRSUIVI)

Who this might be right for
Myeloproliferative NeoplasmEssential ThrombocythemiaPrimary Myelofibrosis, Prefibrotic Stage+1 more
University Hospital, Angers 260
Testing effectiveness (Phase 2)Study completedNCT04554836
What this trial is testing

MoLiMoR - A Study With FOLFIRI-based First-line Therapy With or Without Intermittent Cetuximab

Who this might be right for
Adenocarcinoma of the ColonAdenocarcinoma of the Rectum
TheraOp 6
Testing effectiveness (Phase 2)WithdrawnNCT06331598
What this trial is testing

Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)

Who this might be right for
Solid Tumors
Hoffmann-La Roche
Not applicableStudy completedNCT03997747
What this trial is testing

Cancer Genome Study Using Samples From Patients Treated on Clinical Trial SHR1020-SHR-1210-II-OS

Who this might be right for
Osteosarcoma
Peking University People's Hospital 38
Not applicableLooking for participantsNCT07362225
What this trial is testing

MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)

Who this might be right for
Polycythemia VeraET (Essential Thrombocythemia)Polycythemia Vera (PV)+52 more
MPN Research Foundation 5,000
Not applicableEnded earlyNCT04289259
What this trial is testing

Tumor Mutational Burden in Lung Cancer Patients

Who this might be right for
Non Small Cell Lung CancerNon-Small Cell Carcinoma of LungNon Small Cell Lung Cancer Stage III+1 more
Assistance Publique - Hôpitaux de Paris 6
Testing effectiveness (Phase 2)Study completedNCT02553642
What this trial is testing

Relationship Between Tumor Mutation Burden and Predicted Neo-antigen Burden in Patients With Advanced Melanoma or Bladder Cancer Treated With Nivolumab or Nivolumab Plus Ipilimumab (CA209-260)

Who this might be right for
Bladder CancerMelanoma
Memorial Sloan Kettering Cancer Center 81
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Active Not RecruitingNCT05199272
What this trial is testing

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

Who this might be right for
Solid TumorClear Cell Renal Cell CarcinomaEpithelial Ovarian Cancer+6 more
23andMe, Inc. 141
Testing effectiveness (Phase 2)UnknownNCT03492918
What this trial is testing

Pembrolizumab in Combination With Paclitaxel in the Hormone Receptor-positive Metastatic Breast Cancer With High Tumor Mutational Burden Selected by Whole Exome Sequencing: Korean Cancer Study Group Trial (KCSG BR20-16)

Who this might be right for
Metastatic Breast Cancer
Yonsei University 30
Testing effectiveness (Phase 2)Looking for participantsNCT05093231
What this trial is testing

Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Cambridge University Hospitals NHS Foundation Trust 20
Testing effectiveness (Phase 2)UnknownNCT04185831
What this trial is testing

A MolEcularly Guided Anti-Cancer Drug Off-Label Trial

Who this might be right for
Solid Tumor
Uppsala University Hospital 167
Testing effectiveness (Phase 2)Study completedNCT03836066
What this trial is testing

Atezolizumab Plus Bevacizumab in First Line NSCLC Patients

Who this might be right for
Non Small Cell Lung Cancer
Fundación GECP 41
Not applicableUnknownNCT04263688
What this trial is testing

Multicenter Observational Study of Advanced Non-small Cell Lung Cancer With Malignant Pleural Effusion

Who this might be right for
Non-Small Cell Lung Cancer
Guangzhou Institute of Respiratory Disease 300
Testing effectiveness (Phase 2)UnknownNCT04556071
What this trial is testing

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer

Who this might be right for
Ovarian NeoplasmsFallopian Tube NeoplasmsEndocrine Gland Neoplasms+21 more
Xiaoxiang Chen 32
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