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Results for “Turcot Syndrome”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07403877
What this trial is testing

Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)
Fudan University 114
Large-scale testing (Phase 3)Looking for participantsNCT05770102
What this trial is testing

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

Who this might be right for
MalignancyMalignant NeoplasmLymphoproliferative Disorders+7 more
Cancer Research UK 30
Testing effectiveness (Phase 2)UnknownNCT05371197
What this trial is testing

Envafolimab as Neoadjuvant Immuntherapy in Resectable Local Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
Third Affiliated Hospital, Sun Yat-Sen University 26
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Testing effectiveness (Phase 2)Ended earlyNCT03050814
What this trial is testing

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

Who this might be right for
Colorectal TumorsColorectal NeoplasmsColorectal Carcinoma+2 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Active Not RecruitingNCT05838768
What this trial is testing

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Who this might be right for
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Novartis Pharmaceuticals 123
Very early researchEnded earlyNCT04906382
What this trial is testing

Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer

Who this might be right for
Lynch SyndromeRecurrent Endometrial CarcinomaRecurrent Endometrial Clear Cell Adenocarcinoma+4 more
Floor Backes, MD 2
Testing effectiveness (Phase 2)UnknownNCT05913570
What this trial is testing

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
LiuYing 22
Not applicableUnknownNCT04774367
What this trial is testing

Evaluation of the Reliability of the Determination of MisMatch Repair Deficiency Status by Endoscopic Biopsies in Oesophagus and Gastric Adenocarcinoma.

Who this might be right for
Gastro-oesophageal Adenocarcinoma
Assistance Publique - Hôpitaux de Paris 300
Not applicableStudy completedNCT04482608
What this trial is testing

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Who this might be right for
Colorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High
Sun Yat-sen University 671
Testing effectiveness (Phase 2)UnknownNCT04636008
What this trial is testing

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Who this might be right for
Anti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more
West China Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06278857
What this trial is testing

SATELLITE Study (feaSibility sAfeTy Efficacy dostarLimab earLy-stage defIcient endomeTrial cancEr)

Who this might be right for
Endometrial Cancer Stage IMmr DeficiencyEndometrioid Endometrial Adenocarcinoma+1 more
Queensland Centre for Gynaecological Cancer 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
Not applicableNot Yet RecruitingNCT07780305
What this trial is testing

ABCSG R07 Rectal Cancer Registry

Who this might be right for
Rectal CancerAdenocarcinoma of Rectum
Austrian Breast & Colorectal Cancer Study Group 600
Testing effectiveness (Phase 2)UnknownNCT03475953
What this trial is testing

A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors

Who this might be right for
Colorectal Cancer Not MSI-H or MMR-deficientGISTOesophageal or Gastric Carcinoma+12 more
Institut Bergonié 747
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07369986
What this trial is testing

Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer

Who this might be right for
Endometrial CancerImmunotherapyMismatch Repair Deficiency
Women's Hospital School Of Medicine Zhejiang University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT02983578
What this trial is testing

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Who this might be right for
Advanced Colorectal CarcinomaAdvanced Lung Non-Small Cell CarcinomaLung Non-Small Cell Carcinoma+22 more
M.D. Anderson Cancer Center 39
Not applicableNot Yet RecruitingNCT07360834
What this trial is testing

Study Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in Lynch Syndrome

Who this might be right for
Lynch Syndrome
UNICANCER 2,000
Testing effectiveness (Phase 2)WithdrawnNCT06400264
What this trial is testing

Testing Nivolumab and BMS-986016 (Relatlimab) as Potentially Targeting Treatment in Cancers That Are LAG-3+ and Have Mismatch Repair Deficiency (MATCH - Subprotocol Z1M)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI)
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