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Results for “Type 1 Hyperlipoproteinemia”

43 trials

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Showing 20 of 43 results

Large-scale testing (Phase 3)Study completedNCT02658175
What this trial is testing

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 68
Testing effectiveness (Phase 2)Study completedNCT02767531
What this trial is testing

Orlistat for the Treatment of Type I Hyperlipoproteinemia

Who this might be right for
Hyperlipoproteinemia Type IHypertriglyceridemia
University of Texas Southwestern Medical Center 2
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9
Testing effectiveness (Phase 2)Looking for participantsNCT07223658
What this trial is testing

Study of ARO-DIMERPA in Adult Participants With Mixed Hyperlipidemia

Who this might be right for
Hyperlipidemia; Mixed
Arrowhead Pharmaceuticals 78
Not applicableStudy completedNCT06154408
What this trial is testing

Evaluating the Impact of Omega-3 Fatty Acid Supplementation (Soloways™) on Lipid Profiles in Adults With PPARG Polymorphisms

Who this might be right for
LDL HyperlipoproteinemiaLow-Density-Lipoprotein-Type [LDL] HyperlipoproteinemiaTriglyceride Storage Type I or II Disease
S.LAB (SOLOWAYS) 102
Not applicableNot Yet RecruitingNCT06834204
What this trial is testing

Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer Survivors

Who this might be right for
CancerBreast Cancer Early Stage Breast Cancer (Stage 1-3)Bladder Cancer+5 more
Rutgers, The State University of New Jersey 266
Not applicableStudy completedNCT02656095
What this trial is testing

Lipoprotein Lipase Enzyme Activity Assay Validation and Clinical Assessment

Who this might be right for
Lipoprotein Lipase Deficiency
University of Colorado, Denver 12
Testing effectiveness (Phase 2)Study completedNCT03360747
What this trial is testing

Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 3
Testing effectiveness (Phase 2)Study completedNCT01146522
What this trial is testing

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hyperlipoproteinemia
Novartis Pharmaceuticals 8
Testing effectiveness (Phase 2)Study completedNCT02008084
What this trial is testing

A Pilot Study to Evaluate the Lipid Effects of TRIA-662

Who this might be right for
HypertriglyceridemiaMixed Hyperlipidemia
Cortria Corporation 71
Large-scale testing (Phase 3)Study completedNCT00891306
What this trial is testing

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 5
Not applicableApproved For MarketingNCT06360237
What this trial is testing

Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc.
Very early researchLooking for participantsNCT07371767
What this trial is testing

CS-121 APOC3 Base Editing in Children and Adolescents With Hyperchylomicronemia

Who this might be right for
Hyperchylomicronemia
Shanghai Jiao Tong University School of Medicine 15
Testing effectiveness (Phase 2)Looking for participantsNCT05816343
What this trial is testing

Long Term Efficacy and Safety of Orlistat for Type 1 Hyperlipoproteinemia

Who this might be right for
Type 1 Hyperlipoprotenemia
University of Texas Southwestern Medical Center 28
Not applicableStudy completedNCT02750527
What this trial is testing

Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany

Who this might be right for
Type 1 DiabetesFamilial Hypercholesterolemia
Kinderkrankenhaus auf der Bult 13,049
Not applicableEnded earlyNCT01447901
What this trial is testing

Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies

Who this might be right for
Hyperlipoproteinemia Type I
Amsterdam Molecular Therapeutics 19
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Large-scale testing (Phase 3)Study completedNCT01514461
What this trial is testing

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
Novartis Pharmaceuticals 45
Early research (Phase 1)Study completedNCT05851066
What this trial is testing

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Visirna Therapeutics HK Limited 36
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